CD24
مجموعهٔ تمایزی ۲۴ (انگلیسی: Cluster of Differentiation 24) یا بهاختصار «CD24» که با عناوین دیگری همچون «مبدل سیگنال CD24» و «آنتیژن CD24 پایدار در حرارت» هم شناخته میشود، پروتئینی است که در انسان توسط ژن «CD24» کُد میشود.[۵] این پروتئین، یک «ملکول چسبندگی سلول» است.
این مولکول بر سطح لنفوسیتهای بی و نوروبلاستهای در حالِ تمایز بیان شده و تولید سیالوگلیکوپروتئین را سبب میشود.
منابع
- ↑ ۱٫۰ ۱٫۱ ۱٫۲ GRCh38: Ensembl release 89: ENSG00000272398 – Ensembl, May 2017
- ↑ ۲٫۰ ۲٫۱ ۲٫۲ GRCm38: Ensembl release 89: ENSMUSG00000047139 – Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ Hough MR, Rosten PM, Sexton TL, Kay R, Humphries RK (July 1994). "Mapping of CD24 and homologous sequences to multiple chromosomal loci". Genomics. 22 (1): 154–61. doi:10.1006/geno.1994.1356. PMID 7959762.
- مشارکتکنندگان ویکیپدیا. «CD24». در دانشنامهٔ ویکیپدیای انگلیسی، بازبینیشده در ۱۷ دسامبر ۲۰۱۷.
جستارهای وابسته
- Li D, Zheng L, Jin L, et al. (2009). "CD24 polymorphisms affect risk and progression of chronic hepatitis B virus infection". Hepatology. 50 (3): 735–42. doi:10.1002/hep.23047. PMID 19610054.
- Piotrowski P, Lianeri M, Wudarski M, et al. (2010). "CD24 Ala57Val gene polymorphism and the risk of systemic lupus erythematosus". Tissue Antigens. 75 (6): HASH(0x2aadb3dd8b00). doi:10.1111/j.1399-0039.2010.01447.x. PMID 20230526.
- Honeth G, Bendahl PO, Ringnér M, et al. (2008). "The CD44+/CD24- phenotype is enriched in basal-like breast tumors". Breast Cancer Res. 10 (3): R53. doi:10.1186/bcr2108. PMC 2481503. PMID 18559090.
{{cite journal}}: نگهداری یادکرد:doi رایگان بینشان (رده) - Nagy B, Szendroi A, Romics I (2009). "Overexpression of CD24, c-myc and phospholipase 2A in prostate cancer tissue samples obtained by needle biopsy". Pathol. Oncol. Res. 15 (2): 279–83. doi:10.1007/s12253-008-9077-1. PMID 18752058.
- Kim KH, Choi JS, Kim JM, et al. (2009). "Enhanced CD24 expression in endometrial carcinoma and its expression pattern in normal and hyperplastic endometrium". Histol. Histopathol. 24 (3): 309–16. PMID 19130400.
- Buess M, Rajski M, Vogel-Durrer BM, et al. (2009). "Tumor-endothelial interaction links the CD44(+)/CD24(-) phenotype with poor prognosis in early-stage breast cancer". Neoplasia. 11 (10): 987–1002. PMC 2745665. PMID 19794958.
- Pruszak J, Ludwig W, Blak A, et al. (2009). "CD15, CD24, and CD29 define a surface biomarker code for neural lineage differentiation of stem cells". Stem Cells. 27 (12): 2928–40. doi:10.1002/stem.211. PMC 3322476. PMID 19725119.
- Liu Y, Chen GY, Zheng P (2009). "CD24-Siglec G/10 discriminates danger- from pathogen-associated molecular patterns". Trends Immunol. 30 (12): 557–61. doi:10.1016/j.it.2009.09.006. PMC 2788100. PMID 19786366.
- Vesuna F, Lisok A, Kimble B, Raman V (2009). "Twist modulates breast cancer stem cells by transcriptional regulation of CD24 expression". Neoplasia. 11 (12): 1318–28. PMC 2794513. PMID 20019840.
- Sagiv E, Arber N (2008). "The novel oncogene CD24 and its arising role in the carcinogenesis of the GI tract: from research to therapy". Expert review of gastroenterology & hepatology. 2 (1): 125–33. doi:10.1586/17474124.2.1.125. PMID 19072375.
- Bauerschmitz GJ, Ranki T, Kangasniemi L, et al. (2008). "Tissue-specific promoters active in CD44+CD24-/low breast cancer cells". Cancer Res. 68 (14): 5533–9. doi:10.1158/0008-5472.CAN-07-5288. PMID 18632604.
- Carl JW, Liu JQ, Joshi PS, et al. (2008). "Autoreactive T cells escape clonal deletion in the thymus by a CD24-dependent pathway". J. Immunol. 181 (1): 320–8. doi:10.4049/jimmunol.181.1.320. PMID 18566397.
- Baumhoer D, Riener MO, Zlobec I, et al. (2009). "Expression of CD24, P-cadherin and S100A4 in tumors of the ampulla of Vater". Mod. Pathol. 22 (2): 306–13. doi:10.1038/modpathol.2008.192. PMID 19043399.
- Wang W, Wang X, Peng L, et al. (2010). "CD24-dependent MAPK pathway activation is required for colorectal cancer cell proliferation". Cancer Sci. 101 (1): 112–9. doi:10.1111/j.1349-7006.2009.01370.x. PMID 19860845.
- Sano A, Kato H, Sakurai S, et al. (2009). "CD24 expression is a novel prognostic factor in esophageal squamous cell carcinoma". Ann. Surg. Oncol. 16 (2): 506–14. doi:10.1245/s10434-008-0252-0. PMID 19050962.
- Yang XR, Xu Y, Yu B, et al. (2009). "CD24 is a novel predictor for poor prognosis of hepatocellular carcinoma after surgery". Clin. Cancer Res. 15 (17): 5518–27. doi:10.1158/1078-0432.CCR-09-0151. PMID 19706825.
- Lee JH, Kim SH, Lee ES, Kim YS (2009). "CD24 overexpression in cancer development and progression: a meta-analysis". Oncol. Rep. 22 (5): 1149–56. doi:10.3892/or_00000548. PMID 19787233.
- Gekara NO, Weiss S (2004). "Lipid rafts clustering and signalling by listeriolysin O". Biochem. Soc. Trans. 32 (Pt 5): 712–4. doi:10.1042/BST0320712. PMID 15493995.
- Athanassiadou P, Grapsa D, Gonidi M, et al. (2009). "CD24 expression has a prognostic impact in breast carcinoma". Pathol. Res. Pract. 205 (8): 524–33. doi:10.1016/j.prp.2009.01.008. PMID 19243896.
- Ronaghi M, Vallian S, Etemadifar M (2009). "CD24 gene polymorphism is associated with the disease progression and susceptibility to multiple sclerosis in the Iranian population". Psychiatry Res. 170 (2–3): 271–2. doi:10.1016/j.psychres.2009.01.002. PMID 19896210.
پیوند به بیرون
- CD24 Antigen در سرعنوانهای موضوعی پزشکی (MeSH) در کتابخانهٔ ملی پزشکی ایالات متحدهٔ آمریکا
- مکان ژن انسانی CD24 در مرورگر ژنومی UCSC.
- جزئیات ژن انسانی CD24 در مرورگر ژنومی UCSC.
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