Irwin Rose

Irwin Rose
Rose pada 2000
Kelahiran
Irwin Allan Rose

(1926-07-16)16 Julai 1926
Brooklyn, New York, A.S.
Meninggal dunia2 Jun 2015(2015-06-02) (umur 88)
Deerfield, Massachusetts, A.S.
WarganegaraAmerika Syarikat
Pusat pendidikanUniversiti Chicago (BS, PhD) NYU (postdoc)
Terkenal keranaUbiquitin-mediated protein degradation
PasanganZelda Budenstein
Anak-anak4
AnugerahHadiah Nobel dalam Kimia (2004)
Kerjaya saintifik
BidangBiologi
Institusi

Irwin Allan Rose (16 Julai 1926 - 2 Jun 2015) ialah ahli biologi Amerika. Bersama Aaron Ciechanover dan Avram Hershko, beliau dianugerahkan Hadiah Nobel dalam Kimia 2004 untuk penemuan ubiquitin-mediated degradasi protein.[1][2][3][4][5][6][7]

Rujukan

  1. ^ Wilkinson, Keith; Hershko, Avram (2015). "Irwin Allan Rose (1926–2015) Established role of ubiquitin in the destruction of cellular proteins". Nature. 523 (7562): 532–532. doi:10.1038/523532a. ISSN 0028-0836.
  2. ^ Rose, Irwin (2005), "Early work on the ubiquitin proteasome system, an interview with Irwin Rose. Interview by CDD", Cell Death Differ., 12 (9), m/s. 1162–6, doi:10.1038/sj.cdd.4401700, PMID 16094392
  3. ^ "Nobel Prize in Chemistry, 2004. Aaron Ciechanover, Avram Hershko and Irwin Rose", Indian J. Physiol. Pharmacol., 49 (1), m/s. 121, 2005, PMID 15881872
  4. ^ Latonen, Leena; Laiho, Marikki (2004), "Nobel prize in chemistry goes to three persons with a key role in revealing the ubiquitin-mediated protein degradation pathway", Duodecim; lääketieteellinen aikakauskirja, 120 (24), m/s. 2868–71, PMID 15700582
  5. ^ Goldberg, Alfred L (2005), "Nobel committee tags ubiquitin for distinction", Neuron (diterbitkan Feb 3, 2005), 45 (3), m/s. 339–44, doi:10.1016/j.neuron.2005.01.019, PMID 15694320
  6. ^ Neefjes, J; Groothuis, T A M; Dantuma, N P (2004), "The 2004 Nobel Prize in Chemistry for the discovery of ubiquitin-mediated protein degradation", Nederlands tijdschrift voor geneeskunde (diterbitkan Dec 25, 2004), 148 (52), m/s. 2579–82, PMID 15646859
  7. ^ Hershko, A.; Ciechanover, A.; Rose, I.A. (1979), "Resolution of the ATP-dependent proteolytic system from reticulocytes: a component that interacts with ATP", Proc. Natl. Acad. Sci. USA, 76 (7): 3107–3110, doi:10.1073/pnas.76.7.3107, PMC 383772, PMID 290989.

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