This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor.
Nomenclature
The systematic name of this enzyme class is trans-cinnamate,NADPH:oxygen oxidoreductase (4-hydroxylating). Other names in common use include:
cinnamic acid 4-hydroxylase,
oxygenase, cinnamate 4-mono-,
CA4H (gene name),
CYP73A1 (gene name),
cytochrome P450 cinnamate 4-hydroxylase,
cinnamate 4-hydroxylase,
cinnamate 4-monooxygenase,
cinnamate hydroxylase,
cinnamic 4-hydroxylase,
cinnamic acid 4-monooxygenase,
cinnamic acid p-hydroxylase,
hydroxylase, cinnamate 4-,
t-cinnamic acid hydroxylase,
trans-cinnamate 4-hydroxylase, and
trans-cinnamic acid 4-hydroxylase.
References
Further reading
Potts JR, Weklych R, Conn EE, Rowell J (1974). "The 4-hydroxylation of cinnamic acid by sorghum microsomes and the requirement for cytochrome P-450". J. Biol. Chem. 249 (16): 5019–26. PMID4153152.