ZNF438

ZNF438
Identifikatori
AliasiZNF438
Vanjski ID-jeviMGI: 2444919 HomoloGene: 18695 GeneCards: ZNF438
Lokacija gena (čovjek)
Hromosom 10 (čovjek)
Hrom.Hromosom 10 (čovjek)[1]
Hromosom 10 (čovjek)
Genomska lokacija za ZNF438
Genomska lokacija za ZNF438
Bend10p11.23Početak30,820,207 bp[1]
Kraj31,031,937 bp[1]
Lokacija gena (miš)
Hromosom 18 (miš)
Hrom.Hromosom 18 (miš)[2]
Hromosom 18 (miš)
Genomska lokacija za ZNF438
Genomska lokacija za ZNF438
Bend18|18 A1Početak5,210,029 bp[2]
Kraj5,334,807 bp[2]
Ontologija gena
Molekularna funkcija• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity
• vezivanje sa DNK
• vezivanje iona metala
• nucleic acid binding
• GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
• sequence-specific DNA binding
Ćelijska komponenta• jedro
• nukleoplazma
• citosol
Biološki proces• GO:0045996 negative regulation of transcription, DNA-templated
• GO:0009373 regulation of transcription, DNA-templated
• transcription, DNA-templated
• GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
• GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated
• GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez

220929

240186

Ensembl

ENSG00000183621

ENSMUSG00000050945

UniProt

Q7Z4V0

n/a

RefSeq (mRNK)
NM_001143766
NM_001143767
NM_001143768
NM_001143769
NM_001143770

NM_001143771
NM_182755
NM_001387405
NM_001387411
NM_001387412

NM_178722
NM_001360447

RefSeq (bjelančevina)
NP_001137238
NP_001137239
NP_001137240
NP_001137241
NP_001137242

NP_001137243
NP_877432

n/a

Lokacija (UCSC)Chr 10: 30.82 – 31.03 MbChr 18: 5.21 – 5.33 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Protein cinkovog prsta 438 jest protein koji je kod ljudi kodiran genom ZNF438.[5]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 828 aminokiselina, a molekulska težina 91.836.[6]

1020304050
MQNSVSVPPKDEGESNIPSGTIQSRKGLQNKSQFRTIAPKIVPKVLTSRM
LPCHSPSRSDQVNLGPSINSKLLGMSTQNYALMQVAGQEGTFSLVALPHV
ASAQPIQKPRMSLPENLKLPIPRYQPPRNSKASRKKPILIFPKSGCSKAP
AQTQMCPQMSPSPPHHPELLYKPSPFEEVPSLEQAPASISTAALTNGSDH
GDLRPPVTNTHGSLNPPATPASSTPEEPAKQDLTALSGKAHFVSKITSSK
PSAVASEKFKEQVDLAKTMTNLSPTILGNAVQLISSVPKGKLPIPPYSRM
KTMEVYKIKSDANIAGFSLPGPKADCDKIPSTTEGFNAATKVASRLPVPQ
VSQQSACESAFCPPTKLDLNHKTKLNSGAAKRKGRKRKVPDEILAFQGKR
RKYIINKCRDGKERVKNDPQEFRDQKLGTLKKYRSIMPKPIMVIPTLASL
ASPTTLQSQMLGGLGQDVLLNNSLTPKYLGCKQDNSSSPKPSSVFRNGFS
GIKKPWHRCHVCNHHFQFKQHLRDHMNTHTNRRPYSCRICRKSYVRPGSL
STHMKLHHGENRLKKLMCCEFCAKVFGHIRVYFGHLKEVHRVVISTEPAP
SELQPGDIPKNRDMSVRGMEGSLERENKSNLEEDFLLNQADEVKLQIKCG
RCQITAQSFAEIKFHLLDVHGEEIEGRLQEGTFPGSKGTQEELVQHASPD
WKRHPERGKPEKVHSSSEESHACPRLKRQLHLHQNGVEMLMENEGPQSGT
NKPRETCQGPECPGLHTFLLWSHSGFNCLLCAEMLGRKEDLLHHWKHQHN
CEDPSKLWAILNTVSNQGVIELSSEAEK

Reference

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000183621 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000050945 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Zinc finger protein 438". Pristupljeno 26. 5. 2016.
  6. ^ "UniProt, Q7Z4V0". Pristupljeno 31. 8. 2021.

Dopunska literatura

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