THRAP3
Protein 3 pridružen receptoru tireoidnog hormona jest protein koji je kod ljudi kodiran genom THRAP3 sa hromosoma 1.[5]
Aminokiselinska sekvenca
Dužina polipeptidnog lanca je 955 aminokiselina, a molekulska težina Da. 108 666[6]
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MSKTNKSKSG | SRSSRSRSAS | RSRSRSFSKS | RSRSRSLSRS | RKRRLSSRSR | ||||
| SRSYSPAHNR | ERNHPRVYQN | RDFRGHNRGY | RRPYYFRGRN | RGFYPWGQYN | ||||
| RGGYGNYRSN | WQNYRQAYSP | RRGRSRSRSP | KRRSPSPRSR | SHSRNSDKSS | ||||
| SDRSRRSSSS | RSSSNHSRVE | SSKRKSAKEK | KSSSKDSRPS | QAAGDNQGDE | ||||
| AKEQTFSGGT | SQDTKASESS | KPWPDATYGT | GSASRASAVS | ELSPRERSPA | ||||
| LKSPLQSVVV | RRRSPRPSPV | PKPSPPLSST | SQMGSTLPSG | AGYQSGTHQG | ||||
| QFDHGSGSLS | PSKKSPVGKS | PPSTGSTYGS | SQKEESAASG | GAAYTKRYLE | ||||
| EQKTENGKDK | EQKQTNTDKE | KIKEKGSFSD | TGLGDGKMKS | DSFAPKTDSE | ||||
| KPFRGSQSPK | RYKLRDDFEK | KMADFHKEEM | DDQDKDKAKG | RKESEFDDEP | ||||
| KFMSKVIGAN | KNQEEEKSGK | WEGLVYAPPG | KEKQRKTEEL | EEESFPERSK | ||||
| KEDRGKRSEG | GHRGFVPEKN | FRVTAYKAVQ | EKSSSPPPRK | TSESRDKLGA | ||||
| KGDFPTGKSS | FSITREAQVN | VRMDSFDEDL | ARPSGLLAQE | RKLCRDLVHS | ||||
| NKKEQEFRSI | FQHIQSAQSQ | RSPSELFAQH | IVTIVHHVKE | HHFGSSGMTL | ||||
| HERFTKYLKR | GTEQEAAKNK | KSPEIHRRID | ISPSTFRKHG | LAHDEMKSPR | ||||
| EPGYKAEGKY | KDDPVDLRLD | IERRKKHKER | DLKRGKSRES | VDSRDSSHSR | ||||
| ERSAEKTEKT | HKGSKKQKKH | RRARDRSRSS | SSSSQSSHSY | KAEEYTEETE | ||||
| EREESTTGFD | KSRLGTKDFV | GPSERGGGRA | RGTFQFRARG | RGWGRGNYSG | ||||
| NNNNNSNNDF | QKRNREEEWD | PEYTPKSKKY | YLHDDREGEG | SDKWVSRGRG | ||||
| RGAFPRGRGR | FMFRKSSTSP | KWAHDKFSGE | EGEIEDDESG | TENREEKDNI | ||||
| QPTTE |
Reference
- ^ a b c GRCh38: Ensembl release 89: ENSG00000054118 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000043962 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: THRAP3 thyroid hormone receptor associated protein 3".
- ^ "UniProt, Q9Y2W1" (jezik: en.). Pristupljeno 5. 12. 2021.CS1 održavanje: nepoznati jezik (link)
Dopunska literatura
- Fondell JD, Ge H, Roeder RG (1996). "Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex". Proc. Natl. Acad. Sci. U.S.A. 93 (16): 8329–33. Bibcode:1996PNAS...93.8329F. doi:10.1073/pnas.93.16.8329. PMC 38670. PMID 8710870.
- Ito M, Yuan CX, Malik S, et al. (1999). "Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators". Mol. Cell. 3 (3): 361–70. doi:10.1016/S1097-2765(00)80463-3. PMID 10198638.
- Rachez C, Lemon BD, Suldan Z, et al. (1999). "Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex". Nature. 398 (6730): 824–8. Bibcode:1999Natur.398..824R. doi:10.1038/19783. PMID 10235266. S2CID 204992765.
- Näär AM, Beaurang PA, Zhou S, et al. (1999). "Composite co-activator ARC mediates chromatin-directed transcriptional activation". Nature. 398 (6730): 828–32. Bibcode:1999Natur.398..828N. doi:10.1038/19789. PMID 10235267. S2CID 23646963.
- Ge K, Guermah M, Yuan CX, et al. (2002). "Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis". Nature. 417 (6888): 563–7. Bibcode:2002Natur.417..563G. doi:10.1038/417563a. PMID 12037571. S2CID 4432077.
- Johnson KM, Wang J, Smallwood A, et al. (2002). "TFIID and human mediator coactivator complexes assemble cooperatively on promoter DNA". Genes Dev. 16 (14): 1852–63. doi:10.1101/gad.995702. PMC 186393. PMID 12130544.
- Wang Q, Sharma D, Ren Y, Fondell JD (2003). "A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression". J. Biol. Chem. 277 (45): 42852–8. doi:10.1074/jbc.M206061200. PMID 12218053.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Li J, Hawkins IC, Harvey CD, et al. (2003). "Regulation of Alternative Splicing by SRrp86 and Its Interacting Proteins". Mol. Cell. Biol. 23 (21): 7437–47. doi:10.1128/MCB.23.21.7437-7447.2003. PMC 207616. PMID 14559993.
- Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
- Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
- Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. doi:10.1016/j.cub.2004.07.051. PMID 15324660. S2CID 2371325.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
- Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
- Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
Content Disclaimer
Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.
- The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
- There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
- It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
- Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
- Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.