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THAP6
Identifikatori
Aliasi	THAP6
Vanjski ID-jevi	OMIM: 612535 HomoloGene: 16985 GeneCards: THAP6
Lokacija gena (čovjek)
Hrom.	Hromosom 4 (čovjek)
Kraj	75,550,473 bp
Ontologija gena
Molekularna funkcija	• GO:0001948, GO:0016582 vezivanje za proteine; • vezivanje iona metala; • vezivanje sa DNK; • nucleic acid binding; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Ćelijska komponenta	• microtubule cytoskeleton;
Biološki proces	• GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II;
	Izvori:Amigo / QuickGO
Ortolozi
	152815
	n/a
	ENSG00000174796
	n/a
	Q8TBB0
	n/a
	NM_144721; NM_001317791
	n/a
	NP_001304720; NP_653322; NP_653322.1
	n/a
	Wikipodaci
Pogledaj/uredi – čovjek

Protein 6 sa THAP-domenom jest protein koji je kod ljudi kodiran genom THAP6 sa hromosoma 4.^[3]^[4]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 222 aminokiseline, а molekulska težina 25.691 Da.^[5]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MVKCCSAIGC	ASRCLPNSKL	KGLTFHVFPT	DENIKRKWVL	AMKRLDVNAA
GIWEPKKGDV	LCSRHFKKTD	FDRSAPNIKL	KPGVIPSIFD	SPYHLQGKRE
KLHCRKNFTL	KTVPATNYNH	HLVGASSCIE	EFQSQFIFEH	SYSVMDSPKK
LKHKLDHVIG	ELEDTKESLR	NVLDREKRFQ	KSLRKTIREL	KDECLISQET
ANRLDTFCWD	CCQESIEQDY	IS

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000174796 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Roussigne M, Kossida S, Lavigne AC, Clouaire T, Ecochard V, Glories A, Amalric F, Girard JP (Feb 2003). "The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase". Trends Biochem Sci. 28 (2): 66–9. doi:10.1016/S0968-0004(02)00013-0. PMID 12575992.
^ "Entrez Gene: THAP6 THAP domain containing 6".
^ "UniProt, Q8TBB0" (jezik: engleski). Pristupljeno 29. 10. 2021.

Dopunska literatura

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000174796 - Ensembl, maj 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12575992-3] Roussigne M, Kossida S, Lavigne AC, Clouaire T, Ecochard V, Glories A, Amalric F, Girard JP (Feb 2003). "The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase". Trends Biochem Sci. 28 (2): 66–9. doi:10.1016/S0968-0004(02)00013-0. PMID 12575992.

[entrez-4] "Entrez Gene: THAP6 THAP domain containing 6".

[UniProt-5] "UniProt, Q8TBB0" (jezik: engleski). Pristupljeno 29. 10. 2021.

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THAP6

Aminokiselinska sekvenca

Reference

Dopunska literatura

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