THAP2

THAP2
Dostupne strukture
PDBPretraga ortologa: PDBe RCSB
Spisak PDB ID kodova

2D8R

Identifikatori
AliasiTHAP2
Vanjski ID-jeviOMIM: 612531 MGI: 1914066 HomoloGene: 12039 GeneCards: THAP2
Lokacija gena (čovjek)
Hromosom 12 (čovjek)
Hrom.Hromosom 12 (čovjek)[1]
Hromosom 12 (čovjek)
Genomska lokacija za THAP2
Genomska lokacija za THAP2
Bend12q21.1Početak71,664,301 bp[1]
Kraj71,680,644 bp[1]
Lokacija gena (miš)
Hromosom 10 (miš)
Hrom.Hromosom 10 (miš)[2]
Hromosom 10 (miš)
Genomska lokacija za THAP2
Genomska lokacija za THAP2
Bend10|10 D2Početak115,204,309 bp[2]
Kraj115,220,348 bp[2]
Ontologija gena
Molekularna funkcija• vezivanje iona metala
• vezivanje sa DNK
• nucleic acid binding
• GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
Ćelijska komponenta• Jedarce
Biološki proces• GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez

83591

66816

Ensembl

ENSG00000173451

ENSMUSG00000020137

UniProt

Q9H0W7

Q9D305

RefSeq (mRNK)

NM_031435

NM_025780

RefSeq (bjelančevina)

NP_113623

NP_080056

Lokacija (UCSC)Chr 12: 71.66 – 71.68 MbChr 10: 115.2 – 115.22 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

THAP protein 2 sa domenom je protein koji je kod ljudi kodiran genom THAP2.[5][6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 228 aminokiselina, a molekulska težina 26 260 Da.[7].

1020304050
MPTNCAAAGCATTYNKHINISFHRFPLDPKRRKEWVRLVRRKNFVPGKHT
FLCSKHFEASCFDLTGQTRRLKMDAVPTIFDFCTHIKSMKLKSRNLLKKN
NSCSPAGPSNLKSNISSQQVLLEHSYAFRNPMEAKKRIIKLEKEIASLRR
KMKTCLQKERRATRRWIKATCLVKNLEANSVLPKGTSEHMLPTALSSLPL
EDFKILEQDQQDKTLLSLNLKQTKSTFI

Reference

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000173451 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020137 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Roussigne M, Kossida S, Lavigne AC, Clouaire T, Ecochard V, Glories A, Amalric F, Girard JP (Feb 2003). "The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase". Trends Biochem Sci. 28 (2): 66–9. doi:10.1016/S0968-0004(02)00013-0. PMID 12575992.
  6. ^ "Entrez Gene: THAP2 THAP domain containing, apoptosis associated protein 2".
  7. ^ "UniProt, Q9H0W7". Pristupljeno 14. 8. 2021.

Dopunska literatura

Vanjski linkovi

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