STAMBPL1

STAMBPL1
Dostupne strukture
PDBPretraga ortologa: PDBe RCSB
Spisak PDB ID kodova

2ZNR, 2ZNV

Identifikatori
AliasiSTAMBPL1
Vanjski ID-jeviOMIM: 612352 MGI: 1923880 HomoloGene: 23253 GeneCards: STAMBPL1
Lokacija gena (čovjek)
Hromosom 10 (čovjek)
Hrom.Hromosom 10 (čovjek)[1]
Hromosom 10 (čovjek)
Genomska lokacija za STAMBPL1
Genomska lokacija za STAMBPL1
Bend10q23.31Početak88,879,734 bp[1]
Kraj88,975,153 bp[1]
Lokacija gena (miš)
Hromosom 19 (miš)
Hrom.Hromosom 19 (miš)[2]
Hromosom 19 (miš)
Genomska lokacija za STAMBPL1
Genomska lokacija za STAMBPL1
Bend19|19 C1Početak34,169,629 bp[2]
Kraj34,217,733 bp[2]
Ontologija gena
Molekularna funkcija GO:0070122 peptidase activity
GO:0001948, GO:0016582 vezivanje za proteine
hydrolase activity
metallopeptidase activity
vezivanje iona metala
Lys63-specific deubiquitinase activity
thiol-dependent deubiquitinase
Ćelijska komponenta membrana
citosol
endozom
Biološki proces Proteoliza
protein deubiquitination
protein K63-linked deubiquitination
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_020799

NM_029682
NM_001360716
NM_001360717
NM_001360718
NM_001360719

NM_001360720

RefSeq (bjelančevina)

NP_065850

NP_083958
NP_001347645
NP_001347646
NP_001347647
NP_001347648

NP_001347649

Lokacija (UCSC)Chr 10: 88.88 – 88.98 MbChr 19: 34.17 – 34.22 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

AMSH-olika proteaza je enzim koji je kod ljudi kodiran genom STAMBPL1.[5][6][7]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 436 aminokiselina, а molekulska težina 49.783 Da.[8]

1020304050
MDQPFTVNSLKKLAAMPDHTDVSLSPEERVRALSKLGCNITISEDITPRR
YFRSGVEMERMASVYLEEGNLENAFVLYNKFITLFVEKLPNHRDYQQCAV
PEKQDIMKKLKEIAFPRTDELKNDLLKKYNVEYQEYLQSKNKYKAEILKK
LEHQRLIEAERKRIAQMRQQQLESEQFLFFEDQLKKQELARGQMRSQQTS
GLSEQIDGSALSCFSTHQNNSLLNVFADQPNKSDATNYASHSPPVNRALT
PAATLSAVQNLVVEGLRCVVLPEDLCHKFLQLAESNTVRGIETCGILCGK
LTHNEFTITHVIVPKQSAGPDYCDMENVEELFNVQDQHDLLTLGWIHTHP
TQTAFLSSVDLHTHCSYQLMLPEAIAIVCSPKHKDTGIFRLTNAGMLEVS
ACKKKGFHPHTKEPRLFSICKHVLVKDIKIIVLDLR

Reference

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000138134 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024776 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Kikuchi K, Ishii N, Asao H, Sugamura K (Jun 2003). "Identification of AMSH-LP containing a Jab1/MPN domain metalloenzyme motif". Biochem Biophys Res Commun. 306 (3): 637–43. doi:10.1016/S0006-291X(03)01009-X. PMID 12810066.
  6. ^ Kitajima K, Matsumoto K, Tahara M, Takahashi H, Nakamura T, Nakamura T (Aug 2003). "A newly identified AMSH-family protein is specifically expressed in haploid stages of testicular germ cells". Biochem Biophys Res Commun. 309 (1): 135–42. doi:10.1016/S0006-291X(03)01550-X. PMID 12943674.
  7. ^ "Entrez Gene: STAMBPL1 STAM binding protein-like 1".
  8. ^ "UniProt, Q96FJ0". Pristupljeno 5. 9. 2021.

Dopunska literatura

Vanjski linkovi

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