SDC3

SDC3
Identifikatori
AliasiSDC3
Vanjski ID-jeviOMIM: 186357 MGI: 1349163 HomoloGene: 7965 GeneCards: SDC3
Lokacija gena (čovjek)
Hromosom 1 (čovjek)
Hrom.Hromosom 1 (čovjek)[1]
Hromosom 1 (čovjek)
Genomska lokacija za SDC3
Genomska lokacija za SDC3
Bend1p35.2Početak30,869,466 bp[1]
Kraj30,908,758 bp[1]
Lokacija gena (miš)
Hromosom 4 (miš)
Hrom.Hromosom 4 (miš)[2]
Hromosom 4 (miš)
Genomska lokacija za SDC3
Genomska lokacija za SDC3
Bend4 D2.2|4 63.63 cMPočetak130,519,848 bp[2]
Kraj130,553,630 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija GO:0001948, GO:0016582 vezivanje za proteine
vezivanje identičnih proteina
Ćelijska komponenta integral component of membrane
membrana
ćelijska membrana
lysosomal lumen
Golgi lumen
cell surface
GO:0005578 Vanćelijski matriks
collagen-containing extracellular matrix
microspike
Biološki proces glycosaminoglycan metabolic process
retinoid metabolic process
glycosaminoglycan catabolic process
glycosaminoglycan biosynthetic process
leukocyte migration
Ćelijska migracija
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_014654

NM_011520

RefSeq (bjelančevina)

NP_055469

NP_035650

Lokacija (UCSC)Chr 1: 30.87 – 30.91 MbChr 4: 130.52 – 130.55 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Sindekan-3 jest protein koji je kod ljudi kodiran genom SDC3 sa hromosoma 1.[5][6][7]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 442 aminokiseline, a molekulska težina 45.497 Da.[8]

1020304050
MKPGPPHRAGAAHGAGAGAGAAAGPGARGLLLPPLLLLLLAGRAAGAQRW
RSENFERPVDLEGSGDDDSFPDDELDDLYSGSGSGYFEQESGIETAMRFS
PDVALAVSTTPAVLPTTNIQPVGTPFEELPSERPTLEPATSPLVVTEVPE
EPSQRATTVSTTMATTAATSTGDPTVATVPATVATATPSTPAAPPFTATT
AVIRTTGVRRLLPLPLTTVATARATTPEAPSPPTTAAVLDTEAPTPRLVS
TATSRPRALPRPATTQEPDIPERSTLPLGTTAPGPTEVAQTPTPETFLTT
IRDEPEVPVSGGPSGDFELPEEETTQPDTANEVVAVGGAAAKASSPPGTL
PKGARPGPGLLDNAIDSGSSAAQLPQKSILERKEVLVAVIVGGVVGALFA
AFLVTLLIYRMKKKDEGSYTLEEPKQASVTYQKPDKQEEFYA

Reference

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162512 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025743 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Carey DJ, Evans DM, Stahl RC, Asundi VK, Conner KJ, Garbes P, Cizmeci-Smith G (maj 1992). "Molecular cloning and characterization of N-syndecan, a novel transmembrane heparan sulfate proteoglycan". J Cell Biol. 117 (1): 191–201. doi:10.1083/jcb.117.1.191. PMC 2289399. PMID 1556152.
  6. ^ Berndt C, Casaroli-Marano RP, Vilaro S, Reina M (Aug 2001). "Cloning and characterization of human syndecan-3". J Cell Biochem. 82 (2): 246–59. doi:10.1002/jcb.1119. PMID 11527150. S2CID 1870905.
  7. ^ "Entrez Gene: SDC3 syndecan 3".
  8. ^ "UniProt, O75056" (jezik: eng.). Pristupljeno 5. 12. 2021.CS1 održavanje: nepoznati jezik (link)

Dopunska literatura

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