SARS2
Mitohondrijska seril-tRNK sintetaza je enzim koji je kod ljudi kodiran genom SARS2.[5][6]
Aminokiselinska sekvence
- Simboli
C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MAASMARRLW | PLLTRRGFRP | RGGCISNDSP | RRSFTTEKRN | RNLLYEYARE | ||||
| GYSALPQLDI | ERFCACPEEA | AHALELRKGE | LRSADLPAII | STWQELRQLQ | ||||
| EQIRSLEEEK | AAVTEAVRAL | LANQDSGEVQ | QDPKYQGLRA | RGREIRKELV | ||||
| HLYPREAQLE | EQFYLQALKL | PNQTHPDVPV | GDESQARVLH | MVGDKPVFSF | ||||
| QPRGHLEIGE | KLDIIRQKRL | SHVSGHRSYY | LRGAGALLQH | GLVNFTFNKL | ||||
| LRRGFTPMTV | PDLLRGAVFE | GCGMTPNANP | SQIYNIDPAR | FKDLNLAGTA | ||||
| EVGLAGYFMD | HTVAFRDLPV | RMVCSSTCYR | AETNTGQEPR | GLYRVHHFTK | ||||
| VEMFGVTGPG | LEQSSQLLEE | FLSLQMEILT | ELGLHFRVLD | MPTQELGLPA | ||||
| YRKFDIEAWM | PGRGRFGEVT | SASNCTDFQS | RRLHIMFQTE | AGELQFAHTV | ||||
| NATACAVPRL | LIALLESNQQ | KDGSVLVPPA | LQSYLGTDRI | TAPTHVPLQY | ||||
| IGPNQPRKPG | LPGQPAVS |
Reference
- ^ a b c ENSG00000283104 GRCh38: Ensembl release 89: ENSG00000104835, ENSG00000283104 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000070699 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Yokogawa T, Shimada N, Takeuchi N, Benkowski L, Suzuki T, Omori A, Ueda T, Nishikawa K, Spremulli LL, Watanabe K (Aug 2000). "Characterization and tRNA recognition of mammalian mitochondrial seryl-tRNA synthetase". J Biol Chem. 275 (26): 19913–20. doi:10.1074/jbc.M908473199. PMID 10764807.
- ^ "Entrez Gene: SARS2 seryl-tRNA synthetase 2, mitochondrial".
Dopunska kiteratura
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
- Müller T, Deschauer M, Neudecker S, Zierz S (2007). "Late-onset mitochondrial myopathy with dystrophic changes due to a G7497A mutation in the mitochondrial tRNA(Ser(UCN)) gene". Acta Neuropathol. 110 (4): 426–30. doi:10.1007/s00401-005-1063-z. PMID 16133542. S2CID 23568019.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ihalamulla RL, Liyanage CP, Karunaweera ND (2004). "A simple device to maintain in vitro cultures of Leishmania in tropical countries". Trans. R. Soc. Trop. Med. Hyg. 98 (5): 315–7. doi:10.1016/j.trstmh.2003.10.004. PMID 15109557.
- Gibbons WJ, Yan Q, Li R, et al. (2004). "Genomic organization, expression, and subcellular localization of mouse mitochondrial seryl-tRNA synthetase". Biochem. Biophys. Res. Commun. 317 (3): 774–8. doi:10.1016/j.bbrc.2004.03.113. PMID 15081407.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Casas C, Ribera J, Esquerda JE (2001). "Antibodies against c-Jun N-terminal peptide cross-react with neo-epitopes emerging after caspase-mediated proteolysis during apoptosis". J. Neurochem. 77 (3): 904–15. doi:10.1046/j.1471-4159.2001.00314.x. PMID 11331419. S2CID 27427659.
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