PRB3

PRB3
Identifikatori
AliasiPRB3
Vanjski ID-jeviOMIM: 168840 HomoloGene: 133260 GeneCards: PRB3
Lokacija gena (čovjek)
Hromosom 12 (čovjek)
Hrom.Hromosom 12 (čovjek)[1]
Hromosom 12 (čovjek)
Genomska lokacija za PRB3
Genomska lokacija za PRB3
Bend12p13.2Početak11,265,914 bp[1]
Kraj11,269,707 bp[1]
Obrazac RNK ekspresije


Više referentnih podataka o ekspresiji
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_006249
NM_001394862

n/a

RefSeq (bjelančevina)

n/a

n/a

Lokacija (UCSC)Chr 12: 11.27 – 11.27 Mbn/a
PubMed pretraga[2]n/a
Wikipodaci
Pogledaj/uredi – čovjek

Bazni pljuvačni prolinom bogati protein 3 je protein koji je kod ljudi kodiran genom PRB3.[3][4]

Protein kodiran ovim genom je pljuvačni protein bogat prolin om. Glavni je sastojak parotidne pljuvačke. Predloženo je da ovaj protein djeluje kao bakterijski receptor. Ovaj i pet drugih gena koji također kodiraju pljuvačne proteine bogate prolinom (PRP), kao i gen koji kodira suznu žlijezdu PRP, čine klaster gena PRP u regiji 12p13 hromosoma 12.[4]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 309 aminokiselina, a molekulska težina 30.980 Da.[5].

1020304050
MLLILLSVALLALSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRT
PPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE
GQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGN
QSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPR
PGKPEGPPPQGGNQSQGPPPRPGKPEGSPSQGGNKPQGPPPHPGKPQGPP
PQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPH
RPPQGQPPQ
Simboli

Reference

  1. ^ a b c ENSG00000275624 GRCh38: Ensembl release 89: ENSG00000197870, ENSG00000275624 - Ensembl, maj 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Gillece-Castro BL, Prakobphol A, Burlingame AL, Leffler H, Fisher SJ (Oct 1991). "Structure and bacterial receptor activity of a human salivary proline-rich glycoprotein". J Biol Chem. 266 (26): 17358–68. PMID 1894623.
  4. ^ a b "Entrez Gene: PRB3 proline-rich protein BstNI subfamily 3".
  5. ^ "UniProt, Q04118". Pristupljeno 13. 8. 2021.

Dopunska literatura

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