PHTF2
Pretpostavljeni homeodomenski transkripcijski faktor 2 je protein koji je kod ljudi kodiran genom PHTF2.[5][6]
Aminokiselinska sekvenca
Dužina polipeptidnog lanca je 785 aminokiselina, а molekulska težina 88.757 Da.[7]
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MASKVTDAIV | WYQKKEFLSV | ATTAPGPQQV | LPGYCQCSLK | DQGLFIQCLI | ||||
| GAYDQQIWEK | SVEQREIKFI | KLGLRNKPKK | TAHVKPDLID | VDLVRGSAFA | ||||
| KAKPESPWTS | LTRKGIVRVV | FFPFFFRWWL | QVTSKVIFFW | LLVLYLLQVA | ||||
| AIVLFCSTSS | PHSIPLTEVI | GPIWLMLLLG | TVHCQIVSTR | TPKPPLSTGG | ||||
| KRRRKLRKAA | HLEVHREGDG | SSTTDNTQEG | AVQNHGTSTS | HSVGTVFRDL | ||||
| WHAAFFLSGS | KKAKNSIDKS | TETDNGYVSL | DGKKTVKSGE | DGIQNHEPQC | ||||
| ETIRPEETAW | NTGTLRNGPS | KDTQRTITNV | SDEVSSEEGP | ETGYSLRRHV | ||||
| DRTSEGVLRN | RKSHHYKKHY | PNEDAPKSGT | SCSSRCSSSR | QDSESARPES | ||||
| ETEDVLWEDL | LHCAECHSSC | TSETDVENHQ | INPCVKKEYR | DDPFHQSHLP | ||||
| WLHSSHPGLE | KISAIVWEGN | DCKKADMSVL | EISGMIMNRV | NSHIPGIGYQ | ||||
| IFGNAVSLIL | GLTPFVFRLS | QATDLEQLTA | HSASELYVIA | FGSNEDVIVL | ||||
| SMVIISFVVR | VSLVWIFFFL | LCVAERTYKQ | RLLFAKLFGH | LTSARRARKS | ||||
| EVPHFRLKKV | QNIKMWLSLR | SYLKRRGPQR | SVDVIVSSAF | LLTISVVFIC | ||||
| CAQLLHVHEI | FLDCHYNWEL | VIWCISLTLF | LLRFVTLGSE | TSKKYSNTSI | ||||
| LLTEQINLYL | KMEKKPNKKE | ELTLVNNVLK | LATKLLKELD | SPFRLYGLTM | ||||
| NPLLYNITQV | VILSAVSGVI | SDLLGFNLKL | WKIKS |
Reference
- ^ a b c GRCh38: Ensembl release 89: ENSG00000006576 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039987 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Manuel A, Beaupain D, Romeo PH, Raich N (maj 2000). "Molecular characterization of a novel gene family (PHTF) conserved from Drosophila to mammals". Genomics. 64 (2): 216–20. doi:10.1006/geno.1999.6079. PMID 10729229.
- ^ "Entrez Gene: PHTF2 putative homeodomain transcription factor 2".
- ^ "UniProt, Q8N3S3" (jezik: engleski). Pristupljeno 28. 9. 2021.
Dopunska literatura
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
- Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
- Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
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