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PDAP1
Identifikatori
Aliasi	PDAP1
Vanjski ID-jevi	OMIM: 607075 MGI: 2448536 HomoloGene: 8927 GeneCards: PDAP1
Lokacija gena (čovjek)
Hrom.	Hromosom 7 (čovjek)
Kraj	99,408,597 bp
Lokacija gena (miš)
Hrom.	Hromosom 5 (miš)
Kraj	145,077,048 bp
Obrazac RNK ekspresije
	; ;
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• vezivanje sa RNK;
Ćelijska komponenta	• extracellular region; • ficolin-1-rich granule lumen; • citosol; • ćelijska membrana;
Biološki proces	• GO:0072468 Transdukcija signala; • Ćelijska proliferacija; • neutrophil degranulation;
	Izvori:Amigo / QuickGO
Ortolozi
	11333
	231887
	ENSG00000106244
	ENSMUSG00000029623
	Q13442
	Q3UHX2
	NM_014891
	NM_001033313
	NP_055706
	NP_001028485
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Toplotno i kiselinsko-stabilni fosfoprotein od 28 kDa je protein koji je kod ljudi kodiran genom PDAP1.^[5]^[6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 181 aminokiselina, а molekulska težina 20.630 Da.^[7]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MPKGGRKGGH	KGRARQYTSP	EEIDAQLQAE	KQKAREEEEQ	KEGGDGAAGD
PKKEKKSLDS	DESEDEEDDY	QQKRKGVEGL	IDIENPNRVA	QTTKKVTQLD
LDGPKELSRR	EREEIEKQKA	KERYMKMHLA	GKTEQAKADL	ARLAIIRKQR
EEAARKKEEE	RKAKDDATLS	GKRMQSLSLN	K

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000106244 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029623 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Fischer WH, Schubert D (Jan 1997). "Characterization of a novel platelet-derived growth factor-associated protein". J Neurochem. 66 (5): 2213–6. doi:10.1046/j.1471-4159.1996.66052213.x. PMID 8780057. S2CID 28782367.
^ "Entrez Gene: PDAP1 PDGFA associated protein 1".
^ "UniProt, Q13442" (jezik: engleski). Pristupljeno 27. 9. 2021.

Dopunska literatura

Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Sanger Centre, The; Washington University Genome Sequencing Cente, The (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
LaRochelle WJ, Jeffers M, McDonald WF, et al. (2001). "PDGF-D, a new protease-activated growth factor". Nat. Cell Biol. 3 (5): 517–21. doi:10.1038/35074593. PMID 11331882. S2CID 19633551.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000106244 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029623 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8780057-5] Fischer WH, Schubert D (Jan 1997). "Characterization of a novel platelet-derived growth factor-associated protein". J Neurochem. 66 (5): 2213–6. doi:10.1046/j.1471-4159.1996.66052213.x. PMID 8780057. S2CID 28782367.

[entrez-6] "Entrez Gene: PDAP1 PDGFA associated protein 1".

[UniProt-7] "UniProt, Q13442" (jezik: engleski). Pristupljeno 27. 9. 2021.

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PDAP1

Aminokiselinska sekvenca

Reference

Dopunska literatura

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