MYRIP

MYRIP
Identifikatori
AliasiMYRIP
Vanjski ID-jeviOMIM: 611790 MGI: 2384407 HomoloGene: 9150 GeneCards: MYRIP
Lokacija gena (čovjek)
Hromosom 3 (čovjek)
Hrom.Hromosom 3 (čovjek)[1]
Hromosom 3 (čovjek)
Genomska lokacija za MYRIP
Genomska lokacija za MYRIP
Bend3p22.1Početak39,808,914 bp[1]
Kraj40,260,321 bp[1]
Lokacija gena (miš)
Hromosom 9 (miš)
Hrom.Hromosom 9 (miš)[2]
Hromosom 9 (miš)
Genomska lokacija za MYRIP
Genomska lokacija za MYRIP
Bend9|9 F4Početak120,130,579 bp[2]
Kraj120,303,907 bp[2]
Ontologija gena
Molekularna funkcija• protein kinase A binding
• vezivanje iona cinka
• GO:0001948, GO:0016582 vezivanje za proteine
• vezivanje iona metala
• actin binding
• myosin binding
Ćelijska komponenta• citoplazma
• Melanosom
• perinuklearno područje citoplazme
• photoreceptor outer segment
• exocyst
• sinapsa
• dense core granule
• transport vesicle
• GO:0016023 citoplazmatska vezikula
• actin cytoskeleton
• cortical actin cytoskeleton
Biološki proces• intracellular protein transport
• positive regulation of insulin secretion
• vesicle transport along actin filament
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez

25924

245049

Ensembl

ENSG00000170011

ENSMUSG00000041794

UniProt

Q8NFW9

Q8K3I4

RefSeq (mRNK)

NM_001284423
NM_001284424
NM_001284425
NM_001284426
NM_015460

NM_144557

RefSeq (bjelančevina)

NP_001271352
NP_001271353
NP_001271354
NP_001271355
NP_056275

NP_653140

Lokacija (UCSC)Chr 3: 39.81 – 40.26 MbChr 9: 120.13 – 120.3 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Miozinski VIIA i Rab interaktivni protein jest protein koji je kod ljudi kodiran genom MYRIP sa hromosoma 3.[5]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 859 aminokiselina, а molekulska težina 95.706 Da.[6].

1020304050
MGRKLDLSGLTDDETEHVLQVVQRDFNLRKKEEERLSELKQKLDEEGSKC
SILSKHQQFVEHCCMRCCSPFTFLVNTKRQCGDCKFNVCKSCCSYQKHEK
AWVCCVCQQARLLRAQSLEWFYNNVKSRFKRFGSAKVLKNLYRKHRLESG
ACFDILGGSLFESNLENEGSISGSDSTFYRQSEGHSVMDTLAVALRVAEE
AIEEAISKAEAYGDSLDKQNEASYLRDHKEELTEELATTILQKIIRKQKS
KSEQQVEEEPGWPHPQSCSTKVADEGTSASPGGYRAPAALWRSQSAFSIT
GEEALKTPPVEAPSRQPRDQGQHPRAESALPSWKSVDRLDETNLAPVLQS
PDGNWVALKDGAPPPTRLLAKPKSGTFQALEVASSVASAYDEMGSDSEED
FDWSEALSKLCPRSRALPRNPQPQPTQAQSSDQGPIAASPSSALSPNPEA
MCSDSETSSAGSSREVGHQARLSWLQRKAPRNPAAEKMRLHGELDVNFNP
QLASRETSDSSEPEEAPHTTDRRARRWRRARLGSEEPSKEPSSPSAQLRD
LDTHQVSDDLSETDISNEARDPQTLTDTTEEKRRNRLYELAMKMSEKETS
SGEDQESEPKTESENQKESLSSEDNSQSVQEELKKKFSAVSLCNISTEVL
KVINATEELIAGSTGPWESPQVPPDRQKGMFPRGTDQVRLDEQLTSLEEN
VYLAAGTVYGLETQLTELEDAARCIHSGTDETHLADLEDQVATAAAQVHH
AELQISDIESRISALTIAGLNIAPCVRFTRRRDQKQRTQVQTIDTSRQQR
RKLPAPPVKAEKIETSSVTTIKTFNHNFILQGSSTNRTKERKGTTKDLME
PALESAVMY

Reference

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000170011 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041794 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Myosin VIIA and Rab interacting protein". Pristupljeno 29. 3. 2016.
  6. ^ "UniProt, Q8NFW9" (jezik: engleski). Pristupljeno 4. 11. 2021.

Dopunska literatura

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