MOSPD3

MOSPD3
Identifikatori
AliasiMOSPD3
Vanjski ID-jeviOMIM: 609125 MGI: 1916179 HomoloGene: 11406 GeneCards: MOSPD3
Lokacija gena (čovjek)
Hromosom 7 (čovjek)
Hrom.Hromosom 7 (čovjek)[1]
Hromosom 7 (čovjek)
Genomska lokacija za MOSPD3
Genomska lokacija za MOSPD3
Bend7q22.1Početak100,612,102 bp[1]
Kraj100,615,384 bp[1]
Lokacija gena (miš)
Hromosom 5 (miš)
Hrom.Hromosom 5 (miš)[2]
Hromosom 5 (miš)
Genomska lokacija za MOSPD3
Genomska lokacija za MOSPD3
Bend5 G2|5 76.59 cMPočetak137,594,907 bp[2]
Kraj137,599,320 bp[2]
Ortolozi
VrsteČovjekMiš
Entrez

64598

68929

Ensembl

ENSG00000106330

ENSMUSG00000037221

UniProt

O75425

Q8BGG6

RefSeq (mRNK)
NM_001040097
NM_001040098
NM_001040099
NM_023948
NM_001363415

NM_001363416

NM_001254762
NM_030037

RefSeq (bjelančevina)
NP_001035186
NP_001035187
NP_001035188
NP_076438
NP_001350344

NP_001350345

NP_001241691
NP_084313

Lokacija (UCSC)Chr 7: 100.61 – 100.62 MbChr 5: 137.59 – 137.6 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Protein pokretljivosti spermatozoida sa domenom 3 je protein koji je kod ljudi kodiran genom MOSPD3.[5]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 235 aminokiselina, а molekulska težina 25.519 Da.[6]

1020304050
MRRGAPQDQELVGPGPPGRGSRGAPPPLGPVVPVLVFPPDLVFRADQRSG
PRQLLTLYNPTGTALRFRVLCTAPAKYTVFDAEGYVKPQSCIDIVIRHVA
PIPSHYDVQDRFRIELSEEGAEGRVVGRKDITSILRAPAYPLELQGQPDP
APRPGPPAGTPPPTARHFQEHPRQQLATSSFLLFLLTGIVSVAFLLLPLP
DELGSQLPQVLHVSLGQKLVAAYVLGLLTMVFLRT

Funkcija

Ovaj gen kodira višeprolazni membranski protein s domenom glavni protein sperme (MSP). Delecija sličnog mišjeg gena povezano je s defektnim srčanim razvojem i neonatusnom smrtnošću. Opisane su alternativno prerađene transkripcijske varijante , koje kodiraju različite izoforme.

Reference

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000106330 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037221 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Motile sperm domain containing 3".
  6. ^ "UniProt, O75425" (jezik: engleski). Pristupljeno 2021-09-27.

Dopunska literatura

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