MINDY4

MINDY4
Identifikatori
AliasiMINDY4
Vanjski ID-jeviMGI: 3583959 HomoloGene: 49991 GeneCards: MINDY4
EC broj3.4.19.12
Lokacija gena (čovjek)
Hromosom 7 (čovjek)
Hrom.Hromosom 7 (čovjek)[1]
Hromosom 7 (čovjek)
Genomska lokacija za MINDY4
Genomska lokacija za MINDY4
Bend7p14.3Početak30,771,417 bp[1]
Kraj30,892,387 bp[1]
Lokacija gena (miš)
Hromosom 6 (miš)
Hrom.Hromosom 6 (miš)[2]
Hromosom 6 (miš)
Genomska lokacija za MINDY4
Genomska lokacija za MINDY4
Bend6|6 B3Početak55,180,368 bp[2]
Kraj55,297,207 bp[2]
Ortolozi
VrsteČovjekMiš
Entrez

84182

330323

Ensembl

ENSG00000106125

ENSMUSG00000038022

UniProt

Q4G0A6

Q3UQI9

RefSeq (mRNK)

NM_032222

NM_001142781
NM_177883

RefSeq (bjelančevina)

NP_115598

NP_001136253
NP_808551

Lokacija (UCSC)Chr 7: 30.77 – 30.89 MbChr 6: 55.18 – 55.3 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

MINDY lizin 48-deubikvitinaza 4, znana i kao MINDY4, je ljudski gen.[5]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 757 aminokiselina, а molekulska težina 84.372 Da.[6]

1020304050
MDSLFVEEVAASLVREFLSRKGLKKTCVTMDQERPRSDLSINNRNDLRKV
LHLEFLYKENKAKENPLKTSLELITRYFLDHFGNTANNFTQDTPIPALSV
PKKNNKVPSRCSETTLVNIYDLSDEDAGWRTSLSETSKARHDNLDGDVLG
NFVSSKRPPHKSKPMQTVPGETPVLTSAWEKIDKLHSEPSLDVKRMGENS
RPKSGLIVRGMMSGPIASSPQDSFHRHYLRRSSPSSSSTQPQEESRKVPE
LFVCTQQDILASSNSSPSRTSLGQLSELTVERQKTTASSPPHLPSKRLPP
WDRARPRDPSEDTPAVDGSTDTDRMPLKLYLPGGNSRMTQERLERAFKRQ
GSQPAPVRKNQLLPSDKVDGELGALRLEDVEDELIREEVILSPVPSVLKL
QTASKPIDLSVAKEIKTLLFGSSFCCFNEEWKLQSFSFSNTASLKYGIVQ
NKGGPCGVLAAVQGCVLQKLLFEGDSKADCAQGLQPSDAHRTRCLVLALA
DIVWRAGGRERAVVALASRTQQFSPTGKYKADGVLETLTLHSLTCYEDLV
TFLQQSIHQFEVGPYGCILLTLSAILSRSTELIRQDFDVPTSHLIGAHGY
CTQELVNLLLTGKAVSNVFNDVVELDSGDGNITLLRGIAARSDIGFLSLF
EHYNMCQVGCFLKTPRFPIWVVCSESHFSILFSLQPGLLRDWRTERLFDL
YYYDGLANQQEQIRLTIDTTQTISEDTDNDLVPPLELCIRTKWKGASVNW
NGSDPIL

Predviđanja

Predviđena molekulaka težina je 84.400 Da, a pI je 6,465. pTARGET predviđa da je ćelijska lokacija u Golgijevom aparatu sa 93,9% povjerenja.[7]

Ekspresija

Na osnovu omnibus profila gena za ekspresiju gena ljudskog tkiva, C7orf67 pokazuje značajno povećanje ekspresije u bolesti zvanoj teratospermija.[8]

Reference

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000106125 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038022 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: C7orf67 chromosome 7 open reading frame 67".
  6. ^ "UniProt, Q4G0A6" (jezik: engleski). Pristupljeno 26. 9. 2021.
  7. ^ "Archived copy". Arhivirano s originala, 27. 6. 2009. Pristupljeno 14. 5. 2009.CS1 održavanje: arhivirana kopija u naslovu (link)
  8. ^ "GEO Profiles: GDS2697 record".

Vanjski linkovi

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.