INTS3
Podjedinica 3 integratorskog kompleksa jest protein koji je kod ljudi kodiran genom INTS3 sa hromosoma 1.[5][6]
Aminokiselinska sekvenca
Dužina polipeptidnog lanca je 1.043 aminokiseline, a molekulska težina 118. 070 Da.[7]
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MELQKGKGAA | AAAAASGAAG | GGGGGAGAGA | PGGGRLLLST | SLDAKDELEE | ||||
| RLERCMSIVT | SMTAGVSERE | ANDALNAYVC | KGLPQHEEIC | LGLFTLILTE | ||||
| PAQAQKCYRD | LALVSRDGMN | IVLNKINQIL | MEKYLKLQDT | CRTQLVWLVR | ||||
| ELVKSGVLGA | DGVCMTFMKQ | IAGGGDVTAK | NIWLAESVLD | ILTEQREWVL | ||||
| KSSILIAMAV | YTYLRLIVDH | HGTAQLQALR | QKEVDFCISL | LRERFMECLM | ||||
| IGRDLVRLLQ | NVARIPEFEL | LWKDIIHNPQ | ALSPQFTGIL | QLLQSRTSRK | ||||
| FLACRLTPDM | ETKLLFMTSR | VRFGQQKRYQ | DWFQRQYLST | PDSQSLRCDL | ||||
| IRYICGVVHP | SNEVLSSDIL | PRWAIIGWLL | TTCTSNVAAS | NAKLALFYDW | ||||
| LFFSPDKDSI | MNIEPAILVM | HHSMKPHPAI | TATLLDFMCR | IIPNFYPPLE | ||||
| GHVRQGVFSS | LNHIVEKRVL | AHLAPLFDNP | KLDKELRAML | REKFPEFCSS | ||||
| PSPPVEVKIE | EPVSMEMDNH | MSDKDESCYD | NAEAAFSDDE | EDLNSKGKKR | ||||
| EFRFHPIKET | VVEEPVDITP | YLDQLDESLR | DKVLQLQKGS | DTEAQCEVMQ | ||||
| EIVDQVLEED | FDSEQLSVLA | SCLQELFKAH | FRGEVLPEEI | TEESLEESVG | ||||
| KPLYLIFRNL | CQMQEDNSSF | SLLLDLLSEL | YQKQPKIGYH | LLYYLRASKA | ||||
| AAGKMNLYES | FAQATQLGDL | HTCLMMDMKA | CQEDDVRLLC | HLTPSIYTEF | ||||
| PDETLRSGEL | LNMIVAVIDS | AQLQELVCHV | MMGNLVMFRK | DSVLNILIQS | ||||
| LDWETFEQYC | AWQLFLAHNI | PLETIIPILQ | HLKYKEHPEA | LSCLLLQLRR | ||||
| EKPSEEMVKM | VLSRPCHPDD | QFTTSILRHW | CMKHDELLAE | HIKSLLIKNN | ||||
| SLPRKRQSLR | SSSSKLAQLT | LEQILEHLDN | LRLNLTNTKQ | NFFSQTPILQ | ||||
| ALQHVQASCD | EAHKMKFSDL | FSLAEEYEDS | STKPPKSRRK | AALSSPRSRK | ||||
| NATQPPNAEE | ESGSSSASEE | EDTKPKPTKR | KRKGSSAVGS | DSD |
Reference
- ^ a b c ENSG00000262826 GRCh38: Ensembl release 89: ENSG00000143624, ENSG00000262826 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027933 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N, Shiekhattar R (Oct 2005). "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II". Cell. 123 (2): 265–76. doi:10.1016/j.cell.2005.08.019. PMID 16239144. S2CID 18069461.
- ^ "Entrez Gene: INTS3 integrator complex subunit 3".
- ^ "UniProt, Q68E01" (jezik: en.). Pristupljeno 12. 12. 2021.CS1 održavanje: nepoznati jezik (link)
Dopunska literatura
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Yu Y, Zhang C, Zhou G, et al. (2001). "Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs". Genome Res. 11 (8): 1392–403. doi:10.1101/gr.175501. PMC 311073. PMID 11483580.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Content Disclaimer
Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.
- The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
- There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
- It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
- Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
- Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.