Histoni su osnovni jedarni proteini koji su odgovorni za nukleosomsku strukturu hromosomskog vlakna u eukariotima. Nukleosomi se sastoje od približno 146 bp DNK omotane oko histonskog oktamera, sastavljenog od parova svakog od četiri jezgra histona (H2A, H2B, H3 i H4). Hromatinsko vlakno se dalje sabija kroz interakciju histonskog linkera H1, sa DNK između nukleosoma, kako bi se formirale strukture hromatina višeg reda. Ovaj gen je bez introna i kodira člana porodice histoni H2A. Transkripti ovog gena sadrže palindromski terminacijski element.[6]
Hagiwara T, Hidaka Y, Yamada M (2005). "Deimination of histone H2A and H4 at arginine 3 in HL-60 granulocytes". Biochemistry. 44 (15): 5827–34. doi:10.1021/bi047505c. PMID15823041.
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