GRINA

GRINA
Identifikatori
AliasiGRINA
Vanjski ID-jeviOMIM: 138251 MGI: 1913418 HomoloGene: 41517 GeneCards: GRINA
Lokacija gena (čovjek)
Hromosom 8 (čovjek)
Hrom.Hromosom 8 (čovjek)[1]
Hromosom 8 (čovjek)
Genomska lokacija za GRINA
Genomska lokacija za GRINA
Bend8q24.3Početak143,990,056 bp[1]
Kraj143,993,415 bp[1]
Lokacija gena (miš)
Hromosom 15 (miš)
Hrom.Hromosom 15 (miš)[2]
Hromosom 15 (miš)
Genomska lokacija za GRINA
Genomska lokacija za GRINA
Bend15 D3|15Početak76,130,964 bp[2]
Kraj76,134,104 bp[2]
Ontologija gena
Molekularna funkcija• transmembrane transporter binding
Ćelijska komponenta• integral component of membrane
• Golđijev aparat
• Endoplazmatski retikulum
• membrana
Biološki proces• negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
• endoplasmic reticulum calcium ion homeostasis
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez

2907

66168

Ensembl

ENSG00000178719

ENSMUSG00000022564

UniProt

Q7Z429

Q9ESF4

RefSeq (mRNK)

NM_000837
NM_001009184

NM_023168

RefSeq (bjelančevina)

NP_000828
NP_001009184

NP_075657

Lokacija (UCSC)Chr 8: 143.99 – 143.99 MbChr 15: 76.13 – 76.13 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Ionotropni glutamat-receptor, N-metil D-aspartat-pridruženi protein 1 (glutamat-vezani) je protein koji je kod ljudi kodiran genom GRINA.[5]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 371 aminokiselina, а molekulska težina 41.203 Da.[6]

1020304050
MSHEKSFLVSGDNYPPPNPGYPGGPQPPMPPYAQPPYPGAPYPQPPFQPS
PYGQPGYPHGPSPYPQGGYPQGPYPQGGYPQGPYPQEGYPQGPYPQGGYP
QGPYPQSPFPPNPYGQPQVFPGQDPDSPQHGNYQEEGPPSYYDNQDFPAT
NWDDKSIRQAFIRKVFLVLTLQLSVTLSTVSVFTFVAEVKGFVRENVWTY
YVSYAVFFISLIVLSCCGDFRRKHPWNLVALSVLTASLSYMVGMIASFYN
TEAVIMAVGITTAVCFTVVIFSMQTRYDFTSCMGVLLVSMVVLFIFAILC
IFIRNRILEIVYASLGALLFTCFLAVDTQLLLGNKQLSLSPEEYVFAALN
LYTDIINIFLYILTIIGRAKE

Reference

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000178719 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022564 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)".
  6. ^ "UniProt, Q7Z429" (jezik: engleski). Pristupljeno 18. 9. 2021.

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