DZIP3

DZIP3
Identifikatori
AliasiDZIP3
Vanjski ID-jeviOMIM: 608672 MGI: 1917433 HomoloGene: 8771 GeneCards: DZIP3
EC broj2.3.2.27
Lokacija gena (miš)
Hromosom 16 (miš)
Hrom.Hromosom 16 (miš)[1]
Hromosom 16 (miš)
Genomska lokacija za DZIP3
Genomska lokacija za DZIP3
Bend16|16 B5Početak48,744,595 bp[1]
Kraj48,814,528 bp[1]
Ontologija gena
Molekularna funkcija• phosphatase binding
• polyubiquitin modification-dependent protein binding
• GO:0001948, GO:0016582 vezivanje za proteine
• vezivanje iona metala
• vezivanje sa RNK
• GO:0050372 aktivnost sa transferazom ubikvitina
• aktivnost sa transferazom
• unfolded protein binding
• GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity
• ubiquitin-specific protease binding
Ćelijska komponenta• citoplazma
• Hrd1p ubiquitin ligase complex
• Derlin-1 retrotranslocation complex
• endoplasmic reticulum quality control compartment
Biološki proces• protein polyubiquitination
• protein ubiquitination
• ubiquitin-dependent ERAD pathway
• endoplasmic reticulum unfolded protein response
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez

9666

224170

Ensembl

n/a

ENSMUSG00000064061

UniProt

Q86Y13

Q7TPV2

RefSeq (mRNK)

NM_014648

NM_001110017
NM_027341
NM_001356425

RefSeq (bjelančevina)

NP_055463

NP_001103487
NP_081617
NP_001343354

Lokacija (UCSC)n/aChr 16: 48.74 – 48.81 Mb
PubMed pretraga[2][3]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Protein 3 DAZ interaktivnog cinkovog prsta jest protein koji je kod ljudi kodiran genom DZIP3 sa hromosoma 3.[4]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 1.208 aminokiselina, а molekulska težina 138.604 Da.[5]

1020304050
MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNL
LLEVKKLLNAINTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIV
PALTLRFLITQLEAALRNIQAGNYTAHQINIGYYLTLLFLYGVALTERGK
KEDYTEAENKFLVMKMMIQENEICENFMSLVYFGRGLLRCAQKRYNGGLL
EFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIKTTESNIMKQT
ICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKY
PGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIE
NLGASYRKLISLKITDTDIRPKISLKFNTKDEMPIFKLDYNYFYHLLHII
IISGTDIVRQIFDEAMPPPLLKKELLIHKNVLESYYNHLWTNHPLGGSWH
LLYPPNKELPQSKQFDLCLLLALIKHLNVFPAPKKGWNMEPPSSDISKSA
DILRLCKYRDILLSEILMNGLTESQFNSIWKKVSDILLRLGMMQEDIDKV
KENPIENISLDYHQLSVYLGIPVPEIIQRMLSCYQQGIALQSITGSQRIE
IEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLK
DLQEVKSKQRKKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSR
LIKDDASDVQEDSAMEDKFYSLDELHILDMIEQGSAGKVTTDYGETEKER
LARQRQLYKLHYQCEDFKRQLRTVTFRWQENQMQIKKKDKIIASLNQQVA
FGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHNLESTMKTYVS
KLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNL
ESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQ
LPPPPPSPEILMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPR
APLMTGIAWALPAPVGDAVPPSAGLRSDPSIMNWERITDRLKTAFPQQTR
KELTDFLRKLKDAYGKSLSELTFDEIVCKISQFIDPKKSQSQGKSVSNVN
CVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDEEEEEEEPCVI
CHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGH
PSRQLPKI

References

  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000064061 - Ensembl, maj 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Entrez Gene: DAZ interacting zinc finger protein 3". Pristupljeno 31. 5. 2016.
  5. ^ "UniProt, Q86Y13" (jezik: engleski). Pristupljeno 7. 11. 2021.

Dopunska literatura

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