DPYSL4

DPYSL4
Identifikatori
AliasiDPYSL4
Vanjski ID-jeviOMIM: 608407 MGI: 1349764 HomoloGene: 4691 GeneCards: DPYSL4
Lokacija gena (čovjek)
Hromosom 10 (čovjek)
Hrom.Hromosom 10 (čovjek)[1]
Hromosom 10 (čovjek)
Genomska lokacija za DPYSL4
Genomska lokacija za DPYSL4
Bend10q26.3Početak132,186,948 bp[1]
Kraj132,205,759 bp[1]
Lokacija gena (miš)
Hromosom 7 (miš)
Hrom.Hromosom 7 (miš)[2]
Hromosom 7 (miš)
Genomska lokacija za DPYSL4
Genomska lokacija za DPYSL4
Bend7|7 F4Početak138,665,917 bp[2]
Kraj138,682,620 bp[2]
Obrazac RNK ekspresije


Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija• GO:0001948, GO:0016582 vezivanje za proteine
• hydrolase activity
• hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
• filamin binding
Ćelijska komponenta• citoplazma
• citosol
Biološki proces• neuron death
• neuron projection guidance
• nervous system development
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez

10570

26757

Ensembl

ENSG00000151640

ENSMUSG00000025478

UniProt

O14531

O35098

RefSeq (mRNK)

NM_006426

NM_011993

RefSeq (bjelančevina)

NP_006417

n/a

Lokacija (UCSC)Chr 10: 132.19 – 132.21 MbChr 7: 138.67 – 138.68 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Dihidropirimidinazi srodni protein 4 je enzim koji je kod ljudi kodiran genom DPYSL4.[5][6][7]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 572 aminokiseline, а molekulska težina 61.878.[8]

1020304050
MSFQGKKSIPRITSDRLLIRGGRIVNDDQSFYADVHVEDGLIKQIGENLI
VPGGIKTIDAHGLMVLPGGVDVHTRLQMPVLGMTPADDFCQGTKAALAGG
TTMILDHVFPDTGVSLLAAYEQWRERADSAACCDYSLHVDITRWHESIKE
ELEALVKEKGVNSFLVFMAYKDRCQCSDSQMYEIFSIIRDLGALAQVHAE
NGDIVEEEQKRLLELGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPL
YVTKVMSKGAADAIAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAA
FVTSPPVNPDPTTADHLTCLLSSGDLQVTGSAHCTFTTAQKAVGKDNFAL
IPEGTNGIEERMSMVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGR
VAVGSDADLVIWNPKATKIISAKTHNLNVEYNIFEGVECRGAPAVVISQG
RVALEDGKMFVTPGAGRFVPRKTFPDFVYKRIKARNRLAEIHGVPRGLYD
GPVHEVMVPAKPGSGAPARASCPGKISVPPVRNLHQSGFSLSGSQADDHI
ARRTAQKIMAPPGGRSNITSLS

Reference

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000151640 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025478 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Hamajima N, Matsuda K, Sakata S, Tamaki N, Sasaki M, Nonaka M (Jan 1997). "A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution". Gene. 180 (1–2): 157–63. doi:10.1016/S0378-1119(96)00445-3. PMID 8973361.
  6. ^ Byk T, Ozon S, Sobel A (Jul 1998). "The Ulip family phosphoproteins--common and specific properties". Eur J Biochem. 254 (1): 14–24. doi:10.1046/j.1432-1327.1998.2540014.x. PMID 9652388.
  7. ^ "Entrez Gene: DPYSL4 dihydropyrimidinase-like 4".
  8. ^ "UniProt, O14531". Pristupljeno 1. 9. 2021.

Dopunska literatura

Vanjski linkovi

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.