DOKUMEN123.COM

DNAJC9
Identifikatori
Aliasi	DNAJC9
Vanjski ID-jevi	OMIM: 611206 MGI: 1915326 HomoloGene: 9055 GeneCards: DNAJC9
Lokacija gena (čovjek)
Hrom.	Hromosom 10 (čovjek)
Kraj	73,247,255 bp
Lokacija gena (miš)
Hrom.	Hromosom 14 (miš)
Kraj	20,438,978 bp
Ontologija gena
Molekularna funkcija	• heat shock protein binding; • GO:0001948, GO:0016582 vezivanje za proteine;
Ćelijska komponenta	• membrana; • ćelijska membrana; • jedro; • citoplazma; • Vanćelijsko; • nukleoplazma; • citosol;
Biološki proces	• socijalno ponašanje; • positive regulation of ATP-dependent activity;
	Izvori:Amigo / QuickGO
Ortolozi
	23234
	108671
	ENSG00000213551
	ENSMUSG00000021811
	Q8WXX5
	Q91WN1
	NM_015190
	NM_134081
	NP_056005
	NP_598842
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Član 9 (Hsp40) homologa potporodice DnaJ C je protein koji je kod ljudi kodiran genom DNAJC9.^[5]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 260 aminokiselina, а molekulska težina 29.910.^[6]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MGLLDLCEEV	FGTADLYRVL	GVRREASDGE	VRRGYHKVSL	QVHPDRVGEG
DKEDATRRFQ	ILGKVYSVLS	DREQRAVYDE	QGTVDEDSPV	LTQDRDWEAY
WRLLFKKISL	EDIQAFEKTY	KGSEEELADI	KQAYLDFKGD	MDQIMESVLC
VQYTEEPRIR	NIIQQAIDAG	EVPSYNAFVK	ESKQKMNARK	RRAQEEAKEA
EMSRKELGLD	EGVDSLKAAI	QSRQKDRQKE	MDNFLAQMEA	KYCKSSKGGG
KKSALKKEKK

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000213551 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021811 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: DnaJ (Hsp40) homolog, subfamily C, member 9".
^ "UniProt, Q8WXX5". Pristupljeno 1. 9. 2021.

Dopunska literatura

Takamura Y, Yagi H, Hase K, Yoneda T, Maeda M, Akagi Y, Sato M (juli 2001). "JDD1, a novel member of the DnaJ family, is expressed in the germinal zone of the rat brain". Biochemical and Biophysical Research Communications. 285 (2): 387–92. doi:10.1006/bbrc.2001.5181. PMID 11444854.
Saade E, Mechold U, Kulyyassov A, Vertut D, Lipinski M, Ogryzko V (novembar 2009). "Analysis of interaction partners of H4 histone by a new proteomics approach". Proteomics. 9 (21): 4934–43. arXiv:0910.5822. doi:10.1002/pmic.200900206. PMID 19862764. S2CID 7705719.
Foltz DR, Jansen LE, Bailey AO, Yates JR, Bassett EA, Wood S, Black BE, Cleveland DW (maj 2009). "Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP". Cell. 137 (3): 472–84. doi:10.1016/j.cell.2009.02.039. PMC 2747366. PMID 19410544.
Pan Z, Chen S, Pan X, Wang Z, Han H, Zheng W, Wang X, Li F, Qu S, Shao R (2010). "Differential gene expression identified in Uigur women cervical squamous cell carcinoma by suppression subtractive hybridization". Neoplasma. 57 (2): 123–8. doi:10.4149/neo_2010_02_123. PMID 20099975.
Han C, Chen T, Li N, Yang M, Wan T, Cao X (februar 2007). "HDJC9, a novel human type C DnaJ/HSP40 member interacts with and cochaperones HSP70 through the J domain". Biochemical and Biophysical Research Communications. 353 (2): 280–5. doi:10.1016/j.bbrc.2006.12.013. PMID 17182002.
Crawford NP, Yang H, Mattaini KR, Hunter KW (oktobar 2009). "The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor". The Journal of Biological Chemistry. 284 (42): 28660–73. doi:10.1074/jbc.M109.023457. PMC 2781410. PMID 19710015.
Liu CM, Fann CS, Chen CY, Liu YL, Oyang YJ, Yang WC, Chang CC, Wen CC, Chen WJ, Hwang TJ, Hsieh MH, Liu CC, Faraone SV, Tsuang MT, Hwu HG (juli 2011). "ANXA7, PPP3CB, DNAJC9, and ZMYND17 genes at chromosome 10q22 associated with the subgroup of schizophrenia with deficits in attention and executive function". Biological Psychiatry. 70 (1): 51–8. doi:10.1016/j.biopsych.2011.02.033. PMID 21531385. S2CID 140204042.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000213551 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021811 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: DnaJ (Hsp40) homolog, subfamily C, member 9".

[UniProt-6] "UniProt, Q8WXX5". Pristupljeno 1. 9. 2021.

[1]

[2]

[3]

[4]

[5]

[6]

DNAJC9

Aminokiselinska sekvenca

Reference

Dopunska literatura

Content Disclaimer