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CUTC
Dostupne strukture
PDB	Pretraga ortologa: PDBe RCSB
Spisak PDB ID kodova
	3IWP
Identifikatori
Aliasi	CUTC
Vanjski ID-jevi	OMIM: 610101 MGI: 1913638 HomoloGene: 9318 GeneCards: CUTC
Lokacija gena (čovjek)
Hrom.	Hromosom 10 (čovjek)
Kraj	99,756,134 bp
Lokacija gena (miš)
Hrom.	Hromosom 19 (miš)
Kraj	43,757,077 bp
Obrazac RNK ekspresije
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• copper ion binding; • GO:0001948, GO:0016582 vezivanje za proteine; • vezivanje iona metala;
Ćelijska komponenta	• citoplazma; • Jedarce; • jedro; • nukleoplazma; • citosol;
Biološki proces	• copper ion transport; • protein tetramerization; • copper ion homeostasis;
	Izvori:Amigo / QuickGO
Ortolozi
	51076
	66388
	ENSG00000119929
	ENSMUSG00000025193
	Q9NTM9
	Q9D8X1
	NM_015960
	NM_001113562; NM_025530
	NP_057044
	NP_001107034; NP_079806
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Proteinski cutC homolog homeostaze bakra je protein koji je kod ljudi kodiran genom CUTC.^[5]^[6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 273 aminokiselina, а molekulska težina 29.341.^[7]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MKRQGASSER	KRARIPSGKA	GAANGFLMEV	CVDSVESAVN	AERGGADRIE
LCSGLSEGGT	TPSMGVLQVV	KQSVQIPVFV	MIRPRGGDFL	YSDREIEVMK
ADIRLAKLYG	ADGLVFGALT	EDGHIDKELC	MSLMAICRPL	PVTFHRAFDM
VHDPMAALET	LLTLGFERVL	TSGCDSSALE	GLPLIKRLIE	QAKGRIVVMP
GGGITDRNLQ	RILEGSGATE	FHCSARSTRD	SGMKFRNSSV	AMGASLSCSE
YSLKVTDVTK	VRTLNAIAKN	ILV

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000119929 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025193 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Li J, Ji C, Chen J, Yang Z, Wang Y, Fei X, Zheng M, Gu X, Wen G, Xie Y, Mao Y (Oct 2005). "Identification and characterization of a novel Cut family cDNA that encodes human copper transporter protein CutC". Biochem Biophys Res Commun. 337 (1): 179–83. doi:10.1016/j.bbrc.2005.09.029. PMID 16182249.
^ "Entrez Gene: CUTC cutC copper transporter homolog (E. coli)".
^ "UniProt, Q9NTM9". Pristupljeno 31. 8. 2021.

Dopunska literatura

Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. S2CID 69278.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
Gupta SD, Lee BT, Camakaris J, Wu HC (1995). "Identification of cutC and cutF (nlpE) genes involved in copper tolerance in Escherichia coli". J. Bacteriol. 177 (15): 4207–15. doi:10.1128/jb.177.15.4207-4215.1995. PMC 177164. PMID 7635807.

Vanjski linkovi

Lokacija ljudskog genoma CUTC i stranica sa detaljima o genu CUTC u UCSC Genome Browseru.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000119929 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025193 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16182249-5] Li J, Ji C, Chen J, Yang Z, Wang Y, Fei X, Zheng M, Gu X, Wen G, Xie Y, Mao Y (Oct 2005). "Identification and characterization of a novel Cut family cDNA that encodes human copper transporter protein CutC". Biochem Biophys Res Commun. 337 (1): 179–83. doi:10.1016/j.bbrc.2005.09.029. PMID 16182249.

[entrez-6] "Entrez Gene: CUTC cutC copper transporter homolog (E. coli)".

[UniProt-7] "UniProt, Q9NTM9". Pristupljeno 31. 8. 2021.

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CUTC

Aminokiselinska sekvenca

Reference

Dopunska literatura

Vanjski linkovi

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