CLUH

CLUH
Identifikatori
AliasiCLUH
Vanjski ID-jeviOMIM: 616184 MGI: 1921398 HomoloGene: 9063 GeneCards: CLUH
Lokacija gena (čovjek)
Hromosom 17 (čovjek)
Hrom.Hromosom 17 (čovjek)[1]
Hromosom 17 (čovjek)
Genomska lokacija za CLUH
Genomska lokacija za CLUH
Bend17p13.3Početak2,689,386 bp[1]
Kraj2,712,663 bp[1]
Lokacija gena (miš)
Hromosom 11 (miš)
Hrom.Hromosom 11 (miš)[2]
Hromosom 11 (miš)
Genomska lokacija za CLUH
Genomska lokacija za CLUH
Bend11 B5|11Početak74,540,321 bp[2]
Kraj74,561,673 bp[2]
Ontologija gena
Molekularna funkcija• mRNA binding
• vezivanje sa RNK
Ćelijska komponenta• citoplazma
Biološki proces• intracellular distribution of mitochondria
• mitochondrion organization
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez

23277

74148

Ensembl

ENSG00000132361

ENSMUSG00000020741

UniProt

O75153

Q5SW19

RefSeq (mRNK)

NM_015229

NM_001081158
NM_001368711

RefSeq (bjelančevina)

NP_056044
NP_001353590
NP_001353591

NP_001074627
NP_001355640

Lokacija (UCSC)Chr 17: 2.69 – 2.71 MbChr 11: 74.54 – 74.56 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Klasterirani mitohondrijski (cluA/CLU1) homolog je protein koji je kod ljudi koditran genom CLUH.[5]

Dužina polipeptidnog lanca je 1.309 aminokiselina, sa molekulskom težinom od 146.670[6].

Aminokiselinska sekvenca

Simboli

C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin

1020304050
MLLNGDCPESLKKEAAAAEPPRENGLDEAGPGDETTGQEVIVIQDTGFSV
KILAPGIEPFSLQVSPQEMVQEIHQVLMDREDTCHRTCFSLHLDGNVLDH
FSELRSVEGLQEGSVLRVVEEPYTVREARIHVRHVRDLLKSLDPSDAFNG
VDCNSLSFLSVFTDGDLGDSGKRKKGLEMDPIDCTPPEYILPGSRERPLC
PLQPQNRDWKPLQCLKVLTMSGWNPPPGNRKMHGDLMYLFVITAEDRQVS
ITASTRGFYLNQSTAYHFNPKPASPRFLSHSLVELLNQISPTFKKNFAVL
QKKRVQRHPFERIATPFQVYSWTAPQAEHAMDCVRAEDAYTSRLGYEEHI
PGQTRDWNEELQTTRELPRKNLPERLLRERAIFKVHSDFTAAATRGAMAV
IDGNVMAINPSEETKMQMFIWNNIFFSLGFDVRDHYKDFGGDVAAYVAPT
NDLNGVRTYNAVDVEGLYTLGTVVVDYRGYRVTAQSIIPGILERDQEQSV
IYGSIDFGKTVVSHPRYLELLERTSRPLKILRHQVLNDRDEEVELCSSVE
CKGIIGNDGRHYILDLLRTFPPDLNFLPVPGEELPEECARAGFPRAHRHK
LCCLRQELVDAFVEHRYLLFMKLAALQLMQQNASQLETPSSLENGGPSSL
ESKSEDPPGQEAGSEEEGSSASGLAKVKELAETIAADDGTDPRSREVIRN
ACKAVGSISSTAFDIRFNPDIFSPGVRFPESCQDEVRDQKQLLKDAAAFL
LSCQIPGLVKDCMEHAVLPVDGATLAEVMRQRGINMRYLGKVLELVLRSP
ARHQLDHVFKIGIGELITRSAKHIFKTYLQGVELSGLSAAISHFLNCFLS
SYPNPVAHLPADELVSKKRNKRRKNRPPGAADNTAWAVMTPQELWKNICQ
EAKNYFDFDLECETVDQAVETYGLQKITLLREISLKTGIQVLLKEYSFDS
RHKPAFTEEDVLNIFPVVKHVNPKASDAFHFFQSGQAKVQQGFLKEGCEL
INEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMS
ERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDH
PEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHH
LVARVYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQ
AVALQRTMNEIYRNGSSANIPPLKFTAPSMASVLEQLNVINGILFIPLSQ
KDLENLKAEVARRHQLQEASRNRDRAEEPMATEPAPAGAPGDLGSQPPAA
KDPSPSVQG

Reference

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000132361 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020741 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Clustered mitochondria (cluA/CLU1) homolog". Pristupljeno 15. 4. 2013.
  6. ^ "UniProt, O75153". Pristupljeno September 12, 2017.

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