CASZ1

CASZ1
Identifikatori
AliasiCASZ1
Vanjski ID-jeviOMIM: 609895 MGI: 1196251 HomoloGene: 9824 GeneCards: CASZ1
Lokacija gena (čovjek)
Hromosom 1 (čovjek)
Hrom.Hromosom 1 (čovjek)[1]
Hromosom 1 (čovjek)
Genomska lokacija za CASZ1
Genomska lokacija za CASZ1
Bend1p36.22Početak10,636,604 bp[1]
Kraj10,796,650 bp[1]
Lokacija gena (miš)
Hromosom 4 (miš)
Hrom.Hromosom 4 (miš)[2]
Hromosom 4 (miš)
Genomska lokacija za CASZ1
Genomska lokacija za CASZ1
Bend4 E2|4 78.87 cMPočetak148,888,886 bp[2]
Kraj149,039,346 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija• vezivanje iona metala
• vezivanje sa DNK
• nucleic acid binding
• GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
Ćelijska komponenta• intracellular membrane-bounded organelle
• nukleoplazma
• citosol
• jedro
Biološki proces• multicellular organism development
• GO:0009373 regulation of transcription, DNA-templated
• regulation of neuron differentiation
• GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated
• transcription, DNA-templated
• GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez

54897

69743

Ensembl

ENSG00000130940

ENSMUSG00000028977

UniProt

Q86V15

Q9CWL2

RefSeq (mRNK)

NM_001039183
NM_001079843
NM_017766

NM_001159344
NM_027195

RefSeq (bjelančevina)

NP_001073312
NP_060236

NP_001152816
NP_081471

Lokacija (UCSC)Chr 1: 10.64 – 10.8 MbChr 4: 148.89 – 149.04 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Pretpostavljeni protein vezan za preživljavanje jest protein koji je kod ljudi kodiran genom CASZ1 sa hromosoma 1.[5][6]

Amiokiselininska sekvenca

Dužina polipeptidnog lanca je 1.759 aminokiselina, a molekulska težina Da. 190 069[7]

1020304050
MDLGTAEGTRCTDPPAGKPAMAPKRKGGLKLNAICAKLSRQVVVEKRADA
GSHTEGSPSQPRDQERSGPESGAARAPRSEEDKRRAVIEKWVNGEYSEEP
APTPVLGRIAREGLELPPEGVYMVQPQGCSDEEDHAEEPSKDGGALEEKD
SDGAASKEDSGPSTRQASGEASSLRDYAASTMTEFLGMFGYDDQNTRDEL
ARKISFEKLHAGSTPEAATSSMLPTSEDTLSKRARFSKYEEYIRKLKAGE
QLSWPAPSTKTEERVGKEVVGTLPGLRLPSSTAHLETKATILPLPSHSSV
QMQNLVARASKYDFFIQKLKTGENLRPQNGSTYKKPSKYDLENVKYLHLF
KPGEGSPDMGGAIAFKTGKVGRPSKYDVRGIQKPGPAKVPPTPSLAPAPL
ASVPSAPSAPGPGPEPPASLSFNTPEYLKSTFSKTDSITTGTVSTVKNGL
PTDKPAVTEDVNIYQKYIARFSGSQHCGHIHCAYQYREHYHCLDPECNYQ
RFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTH
YHCMQVGCNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTADC
QFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYK
YEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSS
GALGLPPSLLGAKDTEHEESSNDDLVDFSALSSKNSSLSASPTSQQSSAS
LAAATAATEAGPSATKPPNSKISGLLPQGLPGSIPLALALSNSGLPTPTP
YFPILAGRGSTSLPVGTPSLLGAVSSGSAASATPDTPTLVASGAGDSAPV
AAASVPAPPASIMERISASKGLISPMMARLAAAALKPSATFDPGSGQQVT
PARFPPAQVKPEPGESTGAPGPHEASQDRSLDLTVKEPSNESNGHAVPAN
SSLLSSLMNKMSQGNPGLGSLLNIKAEAEGSPAAEPSPFLGKAVKALVQE
KLAEPWKVYLRRFGTKDFCDGQCDFLHKAHFHCVVEECGALFSTLDGAIK
HANFHFRTEGGAAKGNTEAAFPASAAETKPPMAPSSPPVPPVTTATVSSL
EGPAPSPASVPSTPTLLAWKQLASTIPQMPQIPASVPHLPASPLATTSLE
NAKPQVKPGFLQFQENDPCLATDCKYANKFHFHCLFGNCKYVCKTSGKAE
SHCLDHINPNNNLVNVRDQFAYYSLQCLCPNQHCEFRMRGHYHCLRTGCY
FVTNITTKLPWHIKKHEKAERRAANGFKYFTKREECGRLGCKYNQVNSHF
HCIREGCQFSFLLKHQMTSHARKHMRRMLGKNFDRVPPSQGPPGLMDAET
DECMDYTGCSPGAMSSESSTMDRSCSSTPVGNESTAAGNTISMPTASGAK
KRFWIIEDMSPFGKRRKTASSRKMLDEGMMLEGFRRFDLYEDCKDAACQF
SLKVTHYHCTRENCGYKFCGRTHMYKHAQHHDRVDNLVLDDFKRFKASLS
CHFADCPFSGTSTHFHCLRCRFRCTDSTKVTAHRKHHGKQDVISAAGFCQ
FSSSADCAVPDCKYKLKCSHFHCTFPGCRHTVVGMSQMDSHKRKHEKQER
GEPAAEGPAPGPPISLDGSLSLGAEPGSLLFLQSAAAGLGLALGDAGDPG
PPDAAAPGPREGAAAAAAAAGESSQEDEEEELELPEEEAEDDEDEDDDED
DDDEDDDEDDDDEDLRTDSEESLPEAAAEAAGAGARTPALAALAALGAPG
PAPTAASSP

Reference

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000130940 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028977 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Liu Z, Yang X, Tan F, Cullion K, Thiele CJ (maj 2006). "Molecular cloning and characterization of human Castor, a novel human gene upregulated during cell differentiation". Biochem Biophys Res Commun. 344 (3): 834–44. doi:10.1016/j.bbrc.2006.03.207. PMID 16631614.
  6. ^ "Entrez Gene: CASZ1 castor zinc finger 1".
  7. ^ "UniProt, Q86V15" (jezik: engleski). Pristupljeno 22. 11. 2021.

Dopunska literatura

Vanjski linkovi

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