Premarin

Premarin
Kombinasi
Estron sulfatEstrogen
Ekuilin sulfatEstrogen
Ekuilenin sulfatEstrogen
Data klinikal
Nama lainconjugated estrogens
AHFS/Drugs.comConsumer Drug Information
Kategori
kehamilan
  • X
Kaedah
pemberian		Mulut, topikal, IV
Kod ATC
Status perundangan
Status perundangan
  • In general: ℞ (Preskripsi sahaja)
Data farmakokinetik
Pengikatan protein>90%
Penyingkiran separuh hayat7.2 jam
Perkumuhanrenal
Pengecam
Nombor CAS
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.031.987 Sunting ini di Wikidata
Data kimia dan fizikal
Model 3D (JSmol)
  • [Na+].[O-]S(=O)(=O)Oc1ccc2c(c1)C/C=C3\[C@@H]2CC[C@@]4(C(=O)CC[C@@H]34)C
  • InChI=1S/C18H20O5S.Na/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;/h3-5,10,14,16H,2,6-9H2,1H3,(H,20,21,22);/q;+1/p-1/t14-,16+,18+;/m1./s1 ☑Y
  • Key:QTTMOCOWZLSYSV-QWAPEVOJSA-M ☑Y
  (verify)

Premarin merupakan nama komersial untuk sejenis ubat yang terdiri khusus daripada estrogen-estrogen berkonjugat. Ia diasingkan daripada urin kuda betina bunting (pregnant mares' urine), dan dikilangkan oleh syarikat Wyeth Pharmaceuticals (dinaungi oleh Pfizer sejak Januari 2009) dan dipasarkan sejak tahun 1942. Ia terdapat dalam bentuk suapan mulut (0.3/​0.45/​0.625/​0.9/​1.25 mg), IV, dan topikal (faraj).[1]

Rujukan

  1. ^ Premarin (conjugated estrogens) Vaginal Cream - Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER) -- November 2008

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