Tilmetamine

Tilmetamine
Clinical data
Other namesN-Desethyl-N-methyltiletamine
Drug classDissociative; Hallucinogen
ATC code
  • None
Identifiers
  • 2-(methylamino)-2-thiophen-2-ylcyclohexan-1-one
PubChem CID
Chemical and physical data
FormulaC11H15NOS
Molar mass209.31 g·mol−1
3D model (JSmol)
  • CNC1(CCCCC1=O)C2=CC=CS2
  • InChI=1S/C11H15NOS/c1-12-11(10-6-4-8-14-10)7-3-2-5-9(11)13/h4,6,8,12H,2-3,5,7H2,1H3
  • Key:UIKFZAUDYKWGKI-UHFFFAOYSA-N

Tilmetamine is a dissociative drug of the arylcyclohexylamine family related to tiletamine.[1][2] It is the analogue of tiletamine in which the N-ethyl group has been replaced with an N-methyl group.[1][2] The drug is said to be 3 to 5 times more potent than ketamine and to have a longer duration.[1][2] It is reported to produce adverse effects, such as blurred vision.[1][2] Hamilton Morris and Nervewing have described tilmetamine as producing long-lasting toxicity.[3] Tilmetamine is expected to act as an NMDA receptor antagonist similarly to tiletamine and ketamine.[1][2] It was encountered as a novel designer drug online in August 2024.[1][2]

See also

References

  1. ^ a b c d e f "Тилметамин (Tilmetamine)". AIPSIN (in Russian). Retrieved 9 January 2026.
  2. ^ a b c d e f Yurchenko R, Yurchenko L, Pavlovets Y, Piatsetskaya A, Galetskaya I, Navitski M (September 2024). Psychoactive products market observation. Trend analysis. Monitoring the Psychoactive Product Market. (in Russian). doi:10.13140/RG.2.2.35441.70246. Retrieved 9 January 2026.
  3. ^ Hamilton Morris (12 May 2026). "POD 144: Nervewing on the Joy and Danger of Exploring New Chemical Frontiers". The Hamilton Morris Podcast (Podcast). Patreon.
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