Isooncodine

Isooncodine
Names
IUPAC name
8-Methoxy-4-methyl-1H-indeno[1,2-b]pyridine-5,7-dione
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C14H11NO3/c1-7-3-4-15-13-8-6-11(18-2)10(16)5-9(8)14(17)12(7)13/h3-6,15H,1-2H3
    Key: SQANFQYDLCUUNK-UHFFFAOYSA-N
  • CC1=C2C(=C3C=C(C(=O)C=C3C2=O)OC)NC=C1
Properties
C14H11NO3
Molar mass 241.246 g·mol−1
Appearance Yellowish amorphous powder
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Isooncodine is an anticholinergic alkaloid.[1] It was first synthesized in 1989 because it is an isomer of oncodine, an azafluorenone alkaloid derived from Meiogyne monosperma. It was first derived from the leaves of Polyalthia longifolia.[2]

  1. ^ Naaz, H; Singh, S; Pandey, VP; Singh, P; Dwivedi, UN (2013). "Anti-cholinergic alkaloids as potential therapeutic agents for Alzheimer's disease: An in silico approach". Indian Journal of Biochemistry & Biophysics. 50 (2): 120–5. PMID 23720886.
  2. ^ Wu, Yang-Chang; Duh, Chang-Yih; Wang, Shang-Kwei; Chen, Keh-Shaw; Yang, Tsang-Hsiung (1990-09-01). "Two New Natural Azafluorene Alkaloids and a Cytotoxic Aporphine Alkaloid from Polyalthia longifolia". Journal of Natural Products. 53 (5): 1327–1331. doi:10.1021/np50071a028. ISSN 0163-3864. PMID 2292689.


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