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Anaphase (from Ancient Greek ἀνα- (ana-) 'back, backward' and φάσις (phásis) 'appearance') is the stage of mitosis after the process of metaphase, when...

meiosis I (prophase I, metaphase I, anaphase I, telophase I) and meiosis II (prophase II, metaphase II, anaphase II, telophase II). During meiosis, specific...

preprophase (specific to plant cells), prophase, prometaphase, metaphase, anaphase, and telophase. During mitosis, the chromosomes, which have already duplicated...

Anaphase-promoting complex (also called the cyclosome or APC/C) is an E3 ubiquitin ligase that marks target cell cycle proteins for degradation by the...

anaphase. At this point, the chromosomes are ready to split into opposite poles of the cell toward the spindle to which they are connected. Anaphase is...

second-most condensed and coiled stage (they are at their most condensed in anaphase). These chromosomes, carrying genetic information, align in the equator...

activity falls at anaphase, the inhibitory sites are dephosphorylated and cytokinesis proceeds. MPF is disassembled when anaphase-promoting complex (APC)...

automixis as a sexual process depends on when the products of anaphase I or of anaphase II are joined. The criterion for sexuality varies from all cases...

different mechanisms including chromosome nondisjunction, anaphase lag, and endoreplication. Anaphase lagging is the most common way by which mosaicism arises...

Securin is a protein involved in control of the metaphase-anaphase transition and anaphase onset. Following bi-orientation of chromosome pairs and inactivation...

Anaphase lag is a consequence of an event during cell division where sister chromatids do not properly separate from each other because of improper spindle...

The spindle checkpoint, also known as the metaphase-to-anaphase transition, the spindle assembly checkpoint (SAC), the metaphase checkpoint, or the mitotic...

sister chromatid separation in the anaphase of mitosis. The process can be divided to the following distinct steps: anaphase spindle reorganization, division...

homologous chromosomes and helps them resist being pulled apart until anaphase. Genetic crossing-over, a type of recombination, occurs during the pachytene...

activate the anaphase promoting complex (APC/C), a large 11-13 subunit complex that initiates chromatid separation and entrance into anaphase. The APC/CCdc20...

guide to creating a book on your computer (2nd ed.). San Diego, Calif.: Anaphase II. ISBN 0-945962-14-2. OCLC 54527545. "ISBN Users' Manual (2001 edition)...

degradation starting in anaphase. Experimental addition of non-degradable M-cyclin to cells induces cell cycle arrest in a post-anaphase/pre-telophase-like...

triggering anaphase by hydrolysing cohesin, which is the protein responsible for binding sister chromatids during the early stage of anaphase. In humans...

chromosome attachment to spindle microtubules and prevents cells from starting anaphase until the spindle is built up. The name Mad refers to the observation that...

dyad. Once sister chromatids have separated (during the anaphase of mitosis or the anaphase II of meiosis during sexual reproduction), they are again...

releases its inhibition of the anaphase promoting complex (APC), which in turn irreversibly triggers progression through anaphase.[citation needed] Surveys...

early cell division leads to a fraction of the cells with trisomy 21; An anaphase lag of a chromosome 21 in a Down syndrome embryo leads to a fraction of...

In animal cells, chromosomes reach their highest compaction level in anaphase during chromosome segregation. Chromosomal recombination during meiosis...

daughter cells. Because this event is most prevalent during anaphase, the term anaphase bridge is often used as a substitute. After the formation of...

holocentrism are related to the analysis of the behaviour of chromosomes during anaphase migration since holocentric sister chromatids migrate in parallel to the...

monoamine transporter (PMAT) Four phases of mitosis: prophase, metaphase, anaphase, and telophase: Prophase: Chromatin into chromosomes, the nuclear envelope...

automixis as a sexual process depends on when the products of anaphase I or of anaphase II are joined together. The criterion for "sexuality" varies from...

constriction). The difference between the two constrictions can be noticed during anaphase, as chromosomes can only bend at the site of primary constriction. Secondary...

mitotic spindle apparatus. Following the transition from metaphase to anaphase, the sister chromatids separate from each other, and the individual kinetochores...

stage, an equal maternal, paternal contribution to monosomies is observed. Anaphase lag Miscarriage "CRC - Glossary M". Archived from the original on 2007-08-08...

kinetochores, which actively monitor spindle formation and prevent premature anaphase onset. Microtubule polymerization and depolymerization dynamic drive chromosome...

there are five stages of cell division: Prophase, Prometaphase, Metaphase, Anaphase, and Telophase. During prophase, two aster-covered centrosomes migrate...

undergoing mitosis (which includes pulling of chromatids towards centrioles in anaphase) the cell gathers genetic material from the male and female together. Thus...

product will be dicentric. The dicentric chromatid is pulled apart during anaphase of meiosis I with such force that the chromosome breaks at random positions...

regulatory system that restrains progression through the metaphase-to-anaphase transition. The Mad2 gene was first identified in the yeast S. cerevisiae...

checkpoint or Major Checkpoint; the G2/M checkpoint; and the metaphase-to-anaphase transition, also known as the spindle checkpoint. Progression through these...

Cdh1 (cdc20 homolog 1) is one of the substrate adaptor proteins of the anaphase-promoting complex (APC) in the budding yeast Saccharomyces cerevisiae....

mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation". Genes & Development. 12 (12): 1871–83....

the spindle assembly checkpoint inhibits the anaphase promoting complex. Normally, activation of the anaphase promoting complex leads to the separation of...

chromosomes prior to anaphase. Bub3 and its related proteins that form the Spindle Assembly Checkpoint (SAC) inhibit the action of the Anaphase Promoting Complex...

chromosomes comes not from sperm, but from one of the three polar bodies during anaphase II of meiosis. In honey bees, the genetics of offspring can best be controlled...

microscope. The central nucleus composes the core of the cytoplasm. During anaphase, daughter chromosomes join at the poles of the spindle apparatus, and then...

risk of developmental or degenerative diseases. Micronuclei form during anaphase from lagging acentric chromosomes or chromatid fragments caused by incorrectly...

Cohesin holds sister chromatids together after DNA replication until anaphase when removal of cohesin leads to separation of sister chromatids. The complex...

checkpoint signal. This prevents premature progression into anaphase by inhibiting the anaphase-promoting complex until all kinetochores are attached and...

broken chromatids were rejoined after the chromosome replication. In the anaphase of mitosis, the broken chromosomes formed a chromatid bridge, which was...

The anaphase- promoting complex or cyclosome (APC/C) is a highly specific ubiquitin protein ligase responsible for triggering events of late mitosis. In...

observed that anillin proteolysis is triggered after mitotic exit by the Anaphase Promoting Complex (APC). Most anillins can be sequestered to the nucleus...

ubiquitination of proteins destined for 26S proteasomal degradation. Along with the anaphase-promoting complex, SCF has important roles in the ubiquitination of proteins...

These phases are sequentially known as: prophase prometaphase metaphase anaphase telophase Mitosis is the process by which a eukaryotic cell separates the...

that recognise DNA-binding proteins and repress DNA transcription the anaphase-promoting complex (APC). Examples of both the TPR-TPR interactions, as...

resulting in the timely loss of myosin and Rok from the apical cortex at anaphase onset. The apical myosin flows basally to where the cleavage furrow is...

of homologous centromeres to opposite poles of a dividing cell during anaphase I of meiosis. This occurs by bridging DSN1 kinetochore proteins to sister...

complex also including SKA1 and SKA3 which is responsible for onset of the anaphase in mitosis by regulating chromosomal segregation. SKA2 may function as...

During early anaphase the actomyosin ring and septum continues to develop in budding yeast, in fission yeast during metaphase-anaphase the actomyosin...

plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation...

cycle. Geminin levels drop at the metaphase-anaphase transition of mitosis when it is degraded by the anaphase-promoting complex. During S phase, geminin...

safe for cell division to proceed to completion and for cells to enter anaphase. There are, broadly speaking, two types of centromeres. "Point centromeres"...

loop promotes the inactivation of the cyclin-dependent kinases by the anaphase-promoting complex. This example clearly shows the combined effects that...

mitotic kinases Aurora B and Aurora A. Hesperadin causes cells to enter anaphase much faster, sometimes before the chromosomes are properly bi-oriented...

disassembly event leads to a complete cell cycle arrest. At the end of mitosis, (anaphase, telophase) there is a nuclear reassembly which is highly regulated in...

signaling osteoblast differentiation ubiquitin-dependent ERAD pathway anaphase-promoting complex-dependent catabolic process T cell receptor signaling...

the pre-anaphase stage, cleavage furrows are formed in the spermatocyte cells containing four univalent chromosomes. By the end of the anaphase stage,...

as well as depolymerizing microtubule minus ends at centrosomes during anaphase. Specifically, Kinesin-5 family proteins act within the spindle to slide...

center Cul7-RING ubiquitin ligase complex perinuclear region of cytoplasm anaphase-promoting complex 3M complex cytoskeleton Biological process Golgi organization...

solenoid domain called a TPR domain. Proteins with such domains include the anaphase-promoting complex (APC) subunits cdc16, cdc23 and cdc27, the NADPH oxidase...

performed in vitro biochemical characterisation of the activity of the anaphase-promoting complex (APC) and used cryo-EM to study the APC structure. Passmore...

Anaphase-promoting complex subunit 4 is an enzyme that in humans is encoded by the ANAPC4 gene. A large protein complex, termed the anaphase-promoting...

C-type lectin receptor signaling pathway ubiquitin-dependent ERAD pathway anaphase-promoting complex-dependent catabolic process negative regulation of canonical...

automixis in which there is fusion of the meiotic products formed at the anaphase II stage of meiosis. The venom of hatchlings is as potent as that of the...

cycle regulator which ensures timely mitotic entry by primarily inhibiting Anaphase-Promoting Complex/Cyclosome (APC/C) activity. This protein is present in...

proteolysis Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process proteolysis involved in cellular...

apparatus activates the mitotic checkpoint, preventing cells from entering anaphase to proceed with cell division. Agents that disrupt microtubules therefore...

bridges (UFBs), fine structures that connect sister chromatids during anaphase at some sites such as fragile sites, telomeres and centromeres. This gene...

Anaphase-promoting complex subunit 10 is an enzyme that in humans is encoded by the ANAPC10 gene. ANAPC10 has been shown to interact with CDC27, Mothers...

cascade Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process proteolysis involved in cellular...

metabolic process negative regulation of G2/M transition of mitotic cell cycle anaphase-promoting complex-dependent catabolic process SCF-dependent proteasomal...

method on one chromatid belonging to the sister chromatid complex before anaphase in mitosis. The staining revealed that few segments were passed to the...

unknown; however, there is some evidence suggesting that it plays a role in anaphase. It also contains a relatively well-characterized structural motif called...

containing three copies of a chromosome loses one of these chromosomes (anaphase lag) to form a diploid chromosome complement. If both of the retained chromosomes...

prepares to enter mitosis. Mitosis includes four phases: prophase, metaphase, anaphase, and telophase. Prophase is the initial phase when spindle fibers appear...

second. For example, predivision (the separation of chromatids before anaphase) in the first polar body can induce the formation of an aneuploid polar...

cell division, chromatin facilitates proper segregation of chromosomes in anaphase; the characteristic shapes of chromosomes visible during this stage are...

transcription factors downregulate expression of S phase cyclin genes; anaphase-promoting complex (APC) is activated, which targets and degrades S and...

chromosomes may fail to move to opposite poles of spindle fiber during anaphase. As a result, the chromosome is fragmented, which causes the death of the...

Anaphase-promoting complex subunit 1 is an enzyme that in humans is encoded by the ANAPC1 gene. ANAPC1 is one of at least ten subunits of the anaphase-promoting...

meiosis Nuclear reproduction: mitosis – interphase – prophase – metaphase – anaphase – telophase programmed cell death – apoptosis – cell senescence Metabolism:...

GG (November 1995). "Kinetochore microtubule dynamics and the metaphase-anaphase transition". The Journal of Cell Biology. 131 (3): 721–34. doi:10.1083/jcb...

protein encoded by the APC gene, mutations in which can cause colon cancer Anaphase-promoting complex, a ubiquitin ligase cell cycle protein Antigen-presenting...

Golgi vesicle-mediated transport positive regulation of mitotic metaphase/anaphase transition COPII vesicle coating fibroblast apoptotic process cell projection...

micronucleus is the erratic (third) nucleus that is formed during the anaphase of mitosis or meiosis. Micronuclei (the name means 'small nucleus') are...

protein phosphorylation meiosis G1/S transition of mitotic cell cycle anaphase-promoting complex-dependent catabolic process Sources:Amigo / QuickGO Orthologs...

at the scalp, leading to catagenic miniaturization. Hair follicles in anaphase express four different caspases. Significant levels of inflammatory infiltrate...

Stroschein, S L; Bonni S; Wrana J L; Luo K (November 2001). "Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN". Genes Dev...

is followed or preempted by apoptosis. Prophase Prometaphase Metaphase Anaphase Telophase Cytokinesis Cytoskeleton Marieb E (2000). Essentials of human...

The book's structure is titled "inter-phase", "prophase", "metaphase", "anaphase", "telophase", and "interphase". This mirrors the major phases of cell...

cell cycle progression. Required for chromosome segregation at metaphase-anaphase transition, robust mitotic spindle formation and cytokinesis. Phosphorylates...

Amino acids Amniocentesis Amorph AMP Amphidiploid Amplification Anagenesis Anaphase Aneuploid Aneuploid cell Aneuploidy Angelman syndrome Angiosperm Animal...

"A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression". The Journal of Biological Chemistry. 278 (25): 22828–37....

metaphase and anaphase. STAG3 disassociates with the axes, but stays localized in the centromere, during the transition. Once anaphase is achieved, STAG3...

RING-finger E3 ligases are the largest family and contain ligases such as the anaphase-promoting complex (APC) and the SCF complex (Skp1-Cullin-F-box protein...

segregation occurs at two separate stages during meiosis called anaphase I and anaphase II (see meiosis diagram). In a diploid cell there are two sets...

Cell in anaphase the chromosomes having split and the kinetochore microtubules shrinking...

U-type strand exchange. Under normal separation of sister chromatids in anaphase, the centromere will divide longitudinally, or parallel to the long axis...

degradation of Anaphase Promoting Complex/Cyclosome (APC/C) substrates securin and cyclin B1, which potentially leads to the onset of anaphase I. Cyclin B3...

required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. GRCh38: Ensembl release...

promotes eukaryotic cell cycle and metaphase-to-anaphase transition in particular. In this theory, anaphase promoting complex (APC), a class of ubiquitin...

the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition". Cell. 81 (2): 261–8. doi:10.1016/0092-8674(95)90336-4. PMID 7736578...

in the metaphase-to-anaphase transition and the Spindle Assembly Checkpoint (SAC). Its function also has impacts on the Anaphase Promoting Complex (APC)...

highly similar to Saccharomyces cerevisiae Cdc26, a component of cell cycle anaphase-promoting complex (APC). APC is composed of a group of highly conserved...

PMC 1209167. PMID 17247049. Rhoades, M.M.; Vilkomerson (1942). "On the anaphase movement of chromosomes". Proc. Natl. Acad. Sci. 28 (10): 433–436. Bibcode:1942PNAS...

(With Jean-Claude Guidicelli) (1983) L'Anaphase du Diable [The Devil's Anaphase] (1984) Les Louves Debout [The She-Wolves Standing] (1984) Les Démons de...

Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex". Proc Natl Acad Sci U S A. 94...

This is troublesome for cells that divide often since at the time of anaphase the polycentric chromosome does not move to opposite poles of spindle fiber...

stage of mitosis and meiosis that occurs after prometaphase and before anaphase, during which the centromeres of the replicated chromosomes align along...

The 5.6.7.8's Josh Abrahams Alcotomic Anaphase Arab Strap Architecture in Helsinki Augie March The Avalanches Andrez Bergen Black Rose The Bo-Weevils Blueline...

Book: A Complete Guide to Creating a Book on Your Computer (2nd ed.). Anaphase II. p. 31. ISBN 9780945962144. Addison-Wesley/Benjamin Cummings publishing...

postreplication repair G2-M DNA damage checkpoint M spindle checkpoint, prevents anaphase onset until all chromosomes are properly attached to the spindle Immune...

3:00 8. "Rumeurs" Zaboitzeff 2:35 9. "Rumeurs II" Zaboitzeff 2:56 10. "Anaphase" Hourbette 4:08 11. "Le maitre arrive" Hourbette 2:24 12. "Rumeurs III"...

its dissolution by the cysteine protease Separase at the metaphase to anaphase transition results in the separation of sister chromatids and chromosomal...

these two sister chromatids causes them to fuse with one another. During anaphase the sister chromatids will form a bridge where the centromere in one of...

results in one dicentric chromatid and one acentric chromatid. During Anaphase, both recombinants are faced with problems. The acentric chromatid is pulled...

There is also a more distant member called ANAPC2 (or APC2), part of the Anaphase-promoting complex. CUL1, 2, 3, 4A, 4B, 5 and 7 each form part of a multi-subunit...

of cell cycle variation where mitosis is initiated, but stopped during anaphase and thus cytokinesis is not completed. The cell ends up with multiple nuclei...

PMC 1347501. PMID 16381901. Stegmeier F, Rape M, Draviam VM, et al. (2007). "Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination...

impairment of centromere function, resulting in lagging chromosomes on anaphase during cell division. Small interfering RNA(siRNAs) plays a key role in...

meiosis segregation errors such as nondisjunction, premature disjunction, or anaphase lag during meiosis I or II. For aneuploidy, nondisjunction, the most frequent...

centromere in prometaphase and metaphase, and the central mitotic spindle in anaphase. This localization has been determined by indirect immunofluorescence in...

is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis". Current Biology. 11 (11): 886–890. Bibcode:2001CBio...

opposing sets perpendicular to the plane of the future cell plate during anaphase and telophase. It is initially barrel-shaped and forms from the mitotic...

100} where P, M, A, and T are the number of cells in prophase, metaphase, anaphase, and telophase respectively, and N is the total number of cells. The fastest...

Anaphase-promoting complex subunit 11 is an enzyme that in humans is encoded by the ANAPC11 gene. ANAPC11 has been shown to interact with ANAPC2 and CDC27...

Anaphase-promoting complex subunit 5 is an enzyme that in humans is encoded by the ANAPC5 gene. The anaphase-promoting complex (APC) consists of at least...

NF-kappaB transcription factor activity regulation of inflammatory response anaphase-promoting complex-dependent catabolic process proteolysis involved in cellular...

G, Hengstschläger M, Peters JM (1998-11-05). "Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family". Current Biology...

noted. In multicellular eukaryotes pre-RC assembly is regulated by the anaphase-promoting complex (APC) in addition to CDKs. APC, an E3 enzyme, ubiquitinates...

intact nuclear envelope. The chromatids separate and the nuclei elongate in anaphase. This is followed by an increase in vesicles on the inner membrane. During...

of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1...

metabolic process negative regulation of G2/M transition of mitotic cell cycle anaphase-promoting complex-dependent catabolic process SCF-dependent proteasomal...

process that involves the fusion of the meiotic products formed at the anaphase II stage of meiosis. Three species of the Neotropical pit viper Bothrops...

Medical School in Boston as a postdoctoral fellow. There, he discovered the anaphase promoting complex/cyclosome (APC/C) and other enzymes required for chromosome...

cyclinB/cdc2 complex. Plk phosphorylates and activates components of the anaphase-promoting complex (APC). The APC, which is activated by Fizzy-Cdc20 family...

distinct phases, sequentially known as prophase, prometaphase, metaphase, anaphase and telophase leading to cytokinesis. Cell division is more complex in...

examined for micronuclei, which are fragments or chromosomes left behind at anaphase, and is therefore a test for clastogenic agents that cause chromosome breakages...

histone methylation and centromere formation, causing slow or stalled anaphase during cell division. In some cases, similar processes associated with...

the kinetochore, presumably through detection of tension. Metaphase-to-anaphase transition is halted by the SAC as long as single kinetochores lack bipolar...

that can be used to arrest cells before Anaphase at the spindle assembly checkpoint in the metaphase/anaphase transition. The microtubule poison works...

associated with the mitotic spindle in a highly dynamic manner during anaphase, and localizes to the cell midbody during cytokinesis. PRC1 was first identified...

spindles when disassembly is required to segregate sister chromatids during anaphase. Similar results have been obtained in relation to katanin's activity during...

each of which are necessary for the separation of chromosomes during anaphase of mitosis. Toxicities include bone marrow suppression (which is dose-limiting)...

instability and drop in TPX2 at mitotic exit is dependent on both the anaphase-promoting complex/cyclosome (APC/C) and an ubiquitin ligase integral in...

of spindle formation, but they are mostly corrected before the start of anaphase. Successful cell division requires identification and correction of any...

cerevisiae. Cyclin B1 levels are suppressed throughout G1 and S phases by the anaphase-promoting complex (APC), an E3 ubiquitin ligase which targets cyclin B1...

involving gains or loss of entire chromosomes predominantly occur during anaphase stage of cell division. But these are uncommon in somatic cells because...

remains part of the kinetochore through early anaphase (the chromosome-dividing phase). In late anaphase, CENPF localises to the spindle midzone, and in...

centromere-associated protein required for progression from metaphase to anaphase". EMBO J. 10 (5): 1245–54. doi:10.1002/j.1460-2075.1991.tb08066.x. PMC 452779...

October 2000). "Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast". Cell. 103 (3): 375–386. doi:10.1016/s0092-8674(00)00130-6. ISSN 0092-8674...

This solves the problem of lacking telomeres, but during cell division anaphase, the fused chromosomes are randomly ripped apart, causing many mutations...

cyclin- Cdk complexes. The destruction of M cyclins during metaphase and anaphase, after the Spindle Assembly Checkpoint is satisfied, causes the exit of...

Anaphase-promoting complex subunit 2 is an enzyme that in humans is encoded by the ANAPC2 gene. A large protein complex, termed the anaphase-promoting...

mitosis, meiosis also has distinct stages called prophase, metaphase, anaphase, and telophase. A key difference, however, is that during meiosis, each...

structures formed by mitotic errors in the transition from metaphase to anaphase. Cells with defective chromosome segregation will form micronuclei which...

Maurer-Stroh S, Eisenhaber F, Peters JM (September 2003). "TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1". Current...

The C-terminus region is thought to provide a checkpoint before entering anaphase, provide stability to the holoenzyme, and add proteins to the holoenzyme...

there is no detectable cortical band in metaphase in anaphase. During septation at the end of anaphase, Cdr2 localizes to the contractile ring. After cytokinesis...

maintained at centromeres so that sister chromatids are kept joined until anaphase of meiosis II, at which point removal of remaining cohesin leads to the...

is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis". Curr. Biol. 11 (11): 886–90. Bibcode:2001CBio...

plate) and the two copies separate during anaphase. In some of McIntosh's work he looks specifically at the anaphase A portion, which is related to where the...

based structure, which forms in between segregating chromosomes during anaphase where the two sets of microtubules, emanating from opposite halves of the...

development. They have shown that cortex protein specifically triggers the anaphase-promoting complex in ovaries and the degradation of cortex protein following...

formation of sperm cells. An incident in chromosome separation during anaphase II (of meiosis II) called nondisjunction can result in sperm cells with...

which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Moreover, Emi1 also assembles a CRL1 complex that targets...

PCS will have their centromeres separate during metaphase rather than anaphase (one phase earlier than normal chromosomes). The second chromosomal abnormality...

through the mitosis, might not get separated into their sister chromatids in anaphase. This causes the chromatin to be trapped in the cleavage furrow and form...

Rankin S, Ayad NG, Kirschner MW (2005). "Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates"...

Anaphase-promoting complex subunit 7 is an enzyme that in humans is encoded by the ANAPC7 gene. Multiple transcript variants encoding different isoforms...

(cyclin B), through the dephosphorylation of Cdh1, a regulator of the anaphase-promoting complex. Cdc14 also dephosphorylates Swi5 to enhance transcription...

certain processes) cytoplasm in metaphase and early anaphase, localized to chromosomes in late anaphase, and localized to prenucleolar bodies in late telophase...

process homologous chromosome movement towards spindle pole in meiosis I anaphase establishment of meiotic spindle localization intracellular signal transduction...

catalyse the direct transfer from the E2 enzyme to the substrate. The anaphase-promoting complex (APC) and the SCF complex (for Skp1-Cullin-F-box protein...

replication. This degradation occurs in late mitosis and is regulated by the anaphase promoting complex (APC). Clb1-6 all target and activate the single yeast...

towards the spindle poles by utilizing the dynein motor proteins during anaphase. By understanding the components and mechanisms of intracellular transport...

protein phosphatase Cdc14 from its nucleolar anchor protein Net1 in late anaphase, which is triggered by the action of the mitotic exit network (MEN). In...

attachments early in mitosis, which are then often corrected prior to anaphase onset by a system which uses protein kinase to affect kinetochore microtubules...

structure. During cell division, Barbulanympha has a distinct two-stage anaphase. In anaphase-A, the chromosomal spindle fibres shorten, pulling the chromosomes...

demonstrated that CDC28 protein kinase is not required for the metaphase to anaphase transition and CLB2 proteolysis continues until reactivation of CDC28 toward...

(December 2004). "Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubules". The Journal of Cell Biology. 167 (5): 819–30. doi:10...

in the course the cell cycle, then abruptly disappear just before the anaphase of mitosis. The cyclins are removed via a ubiquitin-mediated proteolytic...

progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and...

the centrosomes in early M phase, the spindle midzone in early and late anaphase and the midbody during cytokinesis. Plks are controlled at the level of...

(2000). "Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast". Cell. 103 (3): 375–386. Bibcode:2000Cell..103..375U. doi:10...

early anaphase before being redistributed to the spindle midzone, after which it is co-localized with midzone microtubules for the duration of anaphase and...

the cell and the spindles attach to the chromosomes haphazardly. When anaphase occurs in these cells, the chromosomes are separated abnormally and results...

chromatids can become entangled and are unable to be separated as normal anaphase commences. These entangled structures are referred to as chromatin bridges...

kinase binding phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity anaphase-promoting complex binding identical protein binding hydrolase activity...

Passmore, Lori Anne (2003). Structural and functional studies of the anaphase promoting complex (APC). london.ac.uk (PhD thesis). University Of London...

of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L2...

and at the spindle assembly checkpoint regulating progression through anaphase. G1 and G2 checkpoints involve scanning for damaged DNA. During S phase...

Profunctor The etymology of anafunctor is an analogy of the biological terms anaphase/prophase. (Roberts 2011) (Makkai 1998) (anafunctor in nlab, §1. Idea) (Makkai...

Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores". Journal of Cell Biology. 198 (2): 173–83. doi:10.1083/jcb...

protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be required to coordinate the onset of sister...

metabolic process negative regulation of G2/M transition of mitotic cell cycle anaphase-promoting complex-dependent catabolic process SCF-dependent proteasomal...

this unusual orientation, the two maternal polar bodies formed during anaphase 1 are extruded from the zygote, leading to the complete elimination of...

purified many of the components involved in cell cycle progression, including anaphase promoting complex (APC), the complex that ubiquitinates cyclin B. A second...

entering metaphase I with errors due to recombination. Prometaphase Metaphase Anaphase Telophase Meiosis Mitosis Cytoskeleton Homologous chromosome Nussbaum RL...

stages of division, such as nuclear membrane breakdown and the metaphase-anaphase transition. Further, recent work has shown mechanically induced rapid entry...

protein binds to centromeres during the prophase, metaphase, and early anaphase cell division stages and to kinetochore microtubules during metaphase....

fragment is frequently lost, while the dicentric fragment forms a bridge at anaphase leading to another chromosomal break. This whole process then repeats itself...

unicentric. Eventually, microtubules extend from the spindle, and during anaphase, they penetrate through the fenestrae and split the nucleus. Subsequently...

and results in inhibition of mitotic cell division between metaphase and anaphase, preventing further cancer cell progeny. Because microtubules do not disassemble...

are related to BRCA. FANC proteins are required to promote BLM-mediated anaphase. FANC proteins also interacts with BRCA1. FANC proteins also interacts...

in S-phase and is degraded at the metaphase-anaphase transition, possibly through ubiquination by anaphase promoting complex (APC). Various cell cycle...

catabolic process NIK/NF-kappaB signaling ubiquitin-dependent ERAD pathway anaphase-promoting complex-dependent catabolic process T cell receptor signaling...

prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until...

between mother and daughter centriole increases until, congruent with anaphase, the diplosome breaks down and each centriole is surrounded by its own...

protein serine/threonine kinase activity regulation of mitotic metaphase/anaphase transition cell cycle negative regulation of cell population proliferation...

pathway NIK/NF-kappaB signaling regulation of protein catabolic process anaphase-promoting complex-dependent catabolic process T cell receptor signaling...

metabolic process negative regulation of G2/M transition of mitotic cell cycle anaphase-promoting complex-dependent catabolic process SCF-dependent proteasomal...

genome size at 63.6 Mbp. The smallest individual chromatids from mitotic anaphase are just 2.1 Mbp and therefore have a size smaller than some bacterial...

proteasomal degradation of cyclin A, whose ubiquitination is promoted by the anaphase promoting complex (APC), an E3 ubiquitin ligase. The APC and the Skp1/Cul1/F-box...

during cytokinesis. Citron-K first appeared at the equatorial cortex in anaphase, concentrated at the cleavage furrow in early telophase, accumulated in...

assembly positive regulation of NF-kappaB transcription factor activity anaphase-promoting complex-dependent catabolic process negative regulation of type...

PMID 9418861. J. Bembenek & H. Yu (December 2001). "Regulation of the anaphase-promoting complex by the dual specificity phosphatase human Cdc14a". The...

characterized by the absence of diatomic oxygen; e.g. anaerobic respiration. anaphase The stage of mitosis and meiosis that occurs after metaphase and before...

of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2". J. Cell Biol. 166 (2): 167–72. doi:10.1083/jcb...

also result in dicentric chromosomes lead to chromosome breakage during anaphase. This further contributes to gene loss on duplicated chromosomes. The duplicated...

orientation. In the absence of TNKs, mitosis arrest is observed in pre-anaphase through Mad2 spindle checkpoint. TNKs can also PARsylate Mcl-1L and Mcl-1S...

stabilize and maintain the central spindle as anaphase proceeds. RACGAP1 can also interact with ECT2 during anaphase of cytokinesis, loss of RACGAP1 leads to...

Drosophila CID/CENP-A and CENP-C into Centromeres during Early Embryonic Anaphase". Current Biology. 17 (3): 237–243. doi:10.1016/j.cub.2006.11.051. ISSN 0960-9822...

quantity of γ-tubulin that normal centrosomes recruit prior to entering anaphase. Though the cell cycle continues even in the absence of sufficient γ-tubulin...

cyclin, which is done through the phosphorylation and dephosphorylation of anaphase-promoting complex (APC). This controls the rate of production of cyclin...

A2 in mammalian cells can result in the delayed onset of metaphase and anaphase. It is also possible that cyclin A2-CDK contributes to tumorigenesis by...

of centrosomal ninein-like protein in human cells is regulated by the anaphase-promoting complex". J. Biol. Chem. 282 (24): 17712–9. doi:10.1074/jbc.M701350200...

(link) Hepler, P. K.; D. A. Callaham (1987). "Free calcium increases during anaphase in stamen hair cells of Tradescantia". Journal of Cell Biology. 105 (5):...

the cell transitions into mitosis, containing four sub stages: prophase, anaphase, metaphase, and telophase. In mitosis, DNA condenses into chromosomes,...

The condition can occur during anaphase in meiosis(I) marking oocyte maturation before ovulation and/or during anaphase in meiosis (II) signifying fertilization...

APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex". Mol. Biol. Cell. 12 (12): 3839–51. doi:10.1091/mbc...

RACGAP1 molecules. This complex localizes to the central spindle during anaphase and the midbody during cytokinesis, where it orchestrates the assembly...

Wutz G, Hill V, Peters JM, et al. (February 2016). "Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations...

into the cytosol early in mitosis, then reaccumulated in nucleus in late anaphase and in telophase. Nevertheless, there is a pool of cIAP1 associated to...

protease that cleaves the cohesive links between sister chromatids to trigger anaphase is a key contribution to our understanding of the cell cycle. He has made...

are shown here. The site of cell division is determined before anaphase. The anaphase spindle (in green on the figure) is then positioned so that the...

and highlighted the separation between two sets of chromosomes during anaphase, telophase and cytokinesis. EosFP has been used to track cell movements...

mechanism that underlies several aspects of mitotic spindle function, e.g. anaphase B spindle elongation. Scholey lab research on mitotic motors and spindle...

assembly positive regulation of NF-kappaB transcription factor activity anaphase-promoting complex-dependent catabolic process negative regulation of type...

periods in tune with the back and forth oscillations of the chromosomes. In anaphase also, the microtubules attached to the chromosomes maintain a carefully...

2006). "The evi5 oncogene regulates cyclin accumulation by stabilizing the anaphase-promoting complex inhibitor emi1". Cell. 124 (2): 367–80. doi:10.1016/j...

Another key component of the cell cycle that is regulated by CBP is the anaphase promoting complex/cyclosome (APC/C). This complex consists of numerous...

is each chromosome is attached to the spindle in the initial stage of anaphase. During normal mitosis, the SAC is active for a short duration of minutes...

with tunnels results from the dissolution of the nuclear membrane. During anaphase, microtubule spindles thread through the plate tunnels and attach to chromatin...

Rankin S, Ayad NG, Kirschner MW (Apr 2005). "Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates"...

275.4.2410. PMID 10644693. Bembenek J, Yu H (2002). "Regulation of the anaphase-promoting complex by the dual specificity phosphatase human Cdc14a". J...

on the chromosome, thereby tearing the chromatid into two pieces during anaphase. The result is a pair of DNAs with broken ends that can attach to other...

NIK/NF-kappaB signaling double-strand break repair via homologous recombination anaphase-promoting complex-dependent catabolic process response to ethanol double-strand...

division, and rounded offspring nuclei form during both early and late anaphase. The interphase cell gradually integrates, developing a conical anterior...

participate in the movement towards the poles of the spindle apparatus during anaphase, but is stretched between the diverging poles. Also during the subsequent...

segregase to separate Cohesin and allow sister chromatid separation in early anaphase. In research as is often the case, scientists test drugs known to have...

of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2". J. Cell Biol. 166 (2): 167–172. doi:10.1083/jcb...

Girdham CH, Glover DM (October 1991). "Chromosome tangling and breakage at anaphase result from mutations in lodestar, a Drosophila gene encoding a putative...

combinations of different gene regulatory factors, the cyclin-Cdk complex and the anaphase-promoting complex (APC). The first major regulatory transition occurs in...

Biological process protein ubiquitination regulation of mitotic metaphase/anaphase transition proteasome-mediated ubiquitin-dependent protein catabolic process...

by the proteasome and induces cell cycle progression from metaphase to anaphase, and eventually into S phase. The resulting extract is referred to as an...

multi-protein complex that inhibits the critical transition from metaphase to anaphase. His more recent work has since shown how this checkpoint functions to...

signaling negative regulation of inflammatory response to antigenic stimulus anaphase-promoting complex-dependent catabolic process proteolysis involved in cellular...

polyubiquitination protein K48-linked ubiquitination ISG15-protein conjugation anaphase-promoting complex-dependent catabolic process histone H2B ubiquitination...

superfamily APC/C activator protein CDH1, cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/C) This disambiguation page lists articles...

chromosome alignment, kinetochore-microtubule interaction, and proper timing of anaphase onset. Dynactin p27 C-terminal T186 residue is phosphorylated by cyclin-dependent...

critical for ensuring the proper separation of sister chromatids during anaphase and provides the mechanical stiffness necessary for their faithful segregation...

inhibitor of the APC/C ubiquitin ligase complex, which is responsible for the anaphase-metaphase transition (by inducing the proteolysis of Securin) and mitotic...

networks controlling the different phases of the cell, such as Cdc14 Early Anaphase Release (FEAR), mitotic exit network (MEN), and regulation of Ace2p (transcription...

product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and...

phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins...

important transitions in the cell cycle. The G1/S, G2/M, and Metaphase–Anaphase transitions all act as biochemical switches in the cell cycle. For instance...

signaling pathway NIK/NF-kappaB signaling type I interferon signaling pathway anaphase-promoting complex-dependent catabolic process proteolysis involved in cellular...

localizes to the centrosome and then to the midzone of mitotic cells from anaphase to cytokinesis. It is expressed about an order of magnitude less than Aurora...

assay) with human lymphocytes is applied. This works in vitro. During anaphase of mitosis of meiosis, micronuclei can be detected. These are small nuclei...

follows interphase. It is composed of four phases - prophase, metaphase, anaphase, and telophase - and involves the condensation of the chromosomes in the...

cascade Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process proteolysis involved in cellular...

protein stability stimulatory C-type lectin receptor signaling pathway anaphase-promoting complex-dependent catabolic process positive regulation of protein...

Stroschein SL, Bonni S, Wrana JL, Luo K (November 2001). "Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN". Genes Dev...

Drosophila CID/CENP-A and CENP-C into centromeres during early embryonic anaphase". Current Biology. 17 (3): 237–243. Bibcode:2007CBio...17..237S. doi:10...

mediator positive regulation of NF-kappaB transcription factor activity anaphase-promoting complex-dependent catabolic process negative regulation of type...

in the Smc3 subunit of cohesin. Smc3 remains acetylated until at least anaphase. Once cohesin has been removed from the chromatin, Smc3 is deacetylated...

335.134.220.220 – cell nucleus division MeSH G04.335.134.220.220.500 – anaphase MeSH G04.335.134.220.220.625 – chromosome segregation MeSH G04.335.134...

proteolysis Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process proteolysis involved in cellular...

Renata Basto studied the control of the transition from metaphase to anaphase in Drosophila. During her postdoc in the lab of Jordan Raff, Renata Basto...

extranuclear bodies that are formed during mitosis from lagging chromosomes. In anaphase, the microtubules are not attached properly to the chromosomes, which can...

of human ubiquitin-conjugating enzyme CDC34 with the mitotic spindle in anaphase". Journal of Cell Science. 113 ( Pt 10) (10): 1687–94. doi:10.1242/jcs...

residues followed by Glu, Tyr, motif on γH2AX. This domain also binds to anaphase-promoting complex (APC/C) which is an E3 ubiquitin ligase that degrades...

CDC16 and CDC27, two tetratricopeptide repeat-containing subunits of the anaphase-promoting complex". The Journal of Biological Chemistry. 272 (51): 32011–8...

consanguinity MeSH G05.105.220 – cell nucleus division MeSH G05.105.220.500 – anaphase MeSH G05.105.220.625 – chromosome segregation MeSH G05.105.220.625.620...

Zur A, Brandeis M, Elroy-Stein O (May 2004). "The Apc5 subunit of the anaphase-promoting complex/cyclosome interacts with poly(A) binding protein and...

N2 and T2 have centromeres found in wild type on chromosome 2. During anaphase of meiosis I, the mechanisms that attach the spindle to the chromosomes...

APC/C motif spans amino acid 222-226 and serves as a binding site for the anaphase-promoting complex. The LIG_FHA_2 motif is involved in the cell checkpoint...

separase, may lead to inappropriate and premature cohesin degradation before anaphase. As a result, homologous chromosomes may align independently on the meiotic...

reverse transcriptase to lengthen telomeres. Overexpression of SMG6 induces anaphase bridges due to chromosome-end fusions and, thus, affects telomere capping...

metaphase and anaphase. Phosphorylating Dis1 leads to localization at the kinetochores during metaphase, whereas dephosphorylation during anaphase leads to...

size at around 61 Mbp. The smallest individual chromatids from mitotic anaphase are just 2.1 Mbp and therefore have a size smaller than some bacterial...

accumulates there during prophase and metaphase, and is depleted during anaphase. KIF18a(-/-) knockout in mice results in complete sterility in males, but...

cascade Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process proteolysis involved in cellular...

Hong KU, Park YS, Seong YS, et al. (2007). "Functional Importance of the Anaphase-Promoting Complex-Cdh1-Mediated Degradation of TMAP/CKAP2 in Regulation...

regulation of G1/S transition of mitotic cell cycle NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process T cell receptor signaling...

V. S.; Benzra, R. (2001). "MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells". Nature. 409 (6818): 355–359...

are removed from histone H2B during metaphase and re-conjugated during anaphase. Histone H2B's amino acid sequence is highly evolutionarily conserved....

catabolic process NIK/NF-kappaB signaling ubiquitin-dependent ERAD pathway anaphase-promoting complex-dependent catabolic process T cell receptor signaling...

response to organonitrogen compound response to amine DNA repair cell cycle anaphase-promoting complex-dependent catabolic process microtubule cytoskeleton...

of the DNA. SMC2 also functions in resolving Sister chromatids prior to Anaphase. SMC2 has been shown to interact with DNMT3B. Mutations in the SMC2 gene...

calculated by summing the number of somatic cells in prophase, metaphase, anaphase, and telophase, then dividing by the total number of quantifiable somatic...

is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may...

of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1...

transition of mitotic cell cycle positive regulation of mitotic metaphase/anaphase transition regulation of centromere complex assembly enucleate erythrocyte...

function in G2/M transition may be linked to the degradation of Pds1 (anaphase inhibitor). And what is more, CDC4 and CDC20, an activator of APC, interact...

Qiao D, Yang X, Meyer K, Friedl A (July 2008). "Glypican-1 regulates anaphase promoting complex/cyclosome substrates and cell cycle progression in endothelial...

Division Cycle Protein 23 Homolog CDC23 Two-hybrid array Component of anaphase-promoting complex/cyclosome. Cytosol, Nucleoplasm Zinc Finger Protein 396...

membrane membrane Biological process cellular senescence G1 to G0 transition anaphase-promoting complex-dependent catabolic process neuropeptide signaling pathway...

maturation spermatogenesis cell cycle mitotic metaphase plate congression anaphase-promoting complex-dependent catabolic process regulation of chromosome...

of the cell before being separated into each of the two daughter cells. Anaphase – The stage of mitosis when chromatids (identical copies of chromosomes)...

replicated sister chromatids, and this is accomplished in part during anaphase A when "kinetochore microtubules (or kMTs)" that link the sister chromatids...

to: American Potash and Chemical Company, American chemical manufacturer Anaphase-promoting complex (sometimes abbreviated as APC/C), an enzyme that regulates...

inhibitor of the APC/C ubiquitin ligase complex, which is responsible for the anaphase-metaphase transition (by inducing the proteolysis of Securin) and mitotic...

stage of cell cycle, displaying chromosome segregation defects (i.e., anaphase bridges) and progressing through abnormal cytokinesis. The requirement...

proteolysis Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process proteolysis involved in cellular...

before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively...

cascade Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process proteolysis involved in cellular...

pathway NIK/NF-kappaB signaling regulation of protein catabolic process anaphase-promoting complex-dependent catabolic process T cell receptor signaling...

signaling pathway NIK/NF-kappaB signaling response to organonitrogen compound anaphase-promoting complex-dependent catabolic process proteolysis involved in cellular...

during prophase and prometaphase, but is dispensable to traverse subsequent anaphase during a round of mitosis. Also, the binding of the Kinesin-5 inhibitors...

mitochondrion cytosol Biological process positive regulation of mitotic metaphase/anaphase transition cell cycle mitotic chromosome movement towards spindle pole...

cascade Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process proteolysis involved in cellular...

ubiquitination cellular response to DNA damage stimulus protein polyubiquitination anaphase-promoting complex-dependent catabolic process post-translational protein...

PMID 25291631. Rhoades, M. M.; Vilkomerson, H. (1942-10-01). "On the Anaphase Movement of Chromosomes". Proceedings of the National Academy of Sciences...

382.374.220.220 – cell nucleus division MeSH G07.382.374.220.220.500 – anaphase MeSH G07.382.374.220.220.625 – chromosome segregation MeSH G07.382.374...

2007. The END network couples spindle pole assembly to inhibition of the anaphase-promoting complex/cyclosome in early mitosis. Developmental Cell 13:29-42...

achieve biorientation and attach correctly to the microtubules during anaphase I. This has been observed in budding yeast, Drosophila melanogaster, and...

assembly positive regulation of NF-kappaB transcription factor activity anaphase-promoting complex-dependent catabolic process negative regulation of type...

"Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex". Nature. 428 (6979): 194–8. Bibcode:2004Natur.428..194W...

estradiol 3-[bis(2-chloroethyl)carbamate] dihydrogen phosphate) – arrests anaphase stage of cell division Prednimustine (Mostarina, Sterecyst; chlorambucil...

cascade Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process proteolysis involved in cellular...

Z; Allshire, R. C (2000). "Live analysis of lagging chromosomes during anaphase and their effect on spindle elongation rate in fission yeast". Journal...

expression data Gene ontology Molecular function DNA binding protein binding anaphase-promoting complex binding Cellular component nucleus nucleoplasm Golgi...

results in silencing. The overall effect of this is the loss of a putative anaphase promoting complex gene. FLC, the flowering locus C gene, which represses...

pathway NIK/NF-kappaB signaling regulation of protein catabolic process anaphase-promoting complex-dependent catabolic process T cell receptor signaling...

STAU1 mRNA levels remain unchanged but STAU1 proteins were degraded by the anaphase-promoting complex (APC) ubiquitin-proteasome system as cells enter mitosis...

metabolic process negative regulation of G2/M transition of mitotic cell cycle anaphase-promoting complex-dependent catabolic process SCF-dependent proteasomal...

transduction positive regulation of MAPK cascade negative regulation of metaphase/anaphase transition of meiotic cell cycle protein phosphorylation Sources:Amigo...

cascade Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process T cell receptor signaling...

is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis". Current Biology. 11 (11): 886–90. Bibcode:2001CBio...

agricultural efficiency could feed an extra three billion people. 20 July – The anaphase-promoting complex – one of the most important and complicated proteins...

chromosomes during the interphase, prophase, prometaphase, and possible anaphase of the cell cycle. Some cells also show pyknotic nuclei typical of cells...

cascade Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process T cell receptor signaling...

C-type lectin receptor signaling pathway ubiquitin-dependent ERAD pathway anaphase-promoting complex-dependent catabolic process negative regulation of canonical...

essential for metaphase chromosome alignment and must be degraded to allow anaphase chromosome movement". Cell. 102 (4): 411–24. doi:10.1016/S0092-8674(00)00047-7...

cascade Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process proteolysis involved in cellular...

ubiquitin-dependent ERAD pathway negative regulation of programmed cell death anaphase-promoting complex-dependent catabolic process negative regulation of transcription...

uptake regulation of cilium assembly positive regulation of metaphase/anaphase transition of meiosis I positive regulation of spindle assembly cellular...

metabolic process negative regulation of G2/M transition of mitotic cell cycle anaphase-promoting complex-dependent catabolic process SCF-dependent proteasomal...

cascade Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process proteolysis involved in cellular...

Geddis AE, Kaushansky K. Endomitotic megakaryocytes form a midzone in anaphase but have a deficiency in cleavage furrow formation. Cell Cycle. 2006; 5:538-545...

signaling pathway positive regulation of canonical Wnt signaling pathway anaphase-promoting complex-dependent catabolic process regulation of proteasomal...

KIF4B and the closely related protein KIF4A are essential for regulating anaphase spindle dynamics during mitosis. GRCh38: Ensembl release 89: ENSG00000226650...

cascade Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process T cell receptor signaling...

proteolysis Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process proteolysis involved in cellular...

"The Lrs4-Csm1 monopolin complex associates with kinetochores during anaphase and is required for accurate chromosome segregation". Cell Cycle. 9 (17):...

Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling meiosis I anaphase-promoting complex-dependent catabolic process T cell receptor signaling...

proteolysis Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process proteolysis involved in cellular...

cascade Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process T cell receptor signaling...

signaling negative regulation of proteasomal protein catabolic process anaphase-promoting complex-dependent catabolic process T cell receptor signaling...

G1/S transition of mitotic cell cycle NIK/NF-kappaB signaling cell cycle anaphase-promoting complex-dependent catabolic process T cell receptor signaling...

polyubiquitination negative regulation of transcription by RNA polymerase II anaphase-promoting complex-dependent catabolic process positive regulation of protein...

Fc-epsilon receptor signaling pathway NIK/NF-kappaB signaling spermatogenesis anaphase-promoting complex-dependent catabolic process T cell receptor signaling...