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Acetergamine

Acetergamine
Names
Systematic IUPAC name
N-{[(8β)-6-Methylergolin-8-yl]methyl}acetamide
Other names
8β-acetylaminomethyl-6-methylergoline
(+)-N-Acetyl-9,10-dihydrolysergamine
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.019.281 Edit this at Wikidata
UNII
  • InChI=1S/C18H23N3O/c1-11(22)19-8-12-6-15-14-4-3-5-16-18(14)13(9-20-16)7-17(15)21(2)10-12/h3-5,9,12,15,17,20H,6-8,10H2,1-2H3,(H,19,22)/t12-,15+,17+/m0/s1
    Key: SGZVEWGAZGOWGP-XGWLTEMNSA-N
  • O=C(NC[C@@H]2C[C@@H]3c4cccc1c4c(c[nH]1)C[C@H]3N(C2)C)C
Properties
C18H23N3O
Molar mass 297.402 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Acetergamine is an organic chemical compound; specifically it is a derivative of ergoline, making it a member of the ergotamine family of compounds. Acetergamine currently has no mainstream uses, however its potential as an alpha-1 blocker and vasodilator has led to it being covered in several patents concerning therapies for erectile dysfunction. It has also been investigated as a treatment for cerebellar ataxia.[1]

References

  1. ^ Ogawa, M (2004). "Pharmacological treatments of cerebellar ataxia". Cerebellum. 3 (2). London): 107–11. doi:10.1080/147342204100032331. PMID 15233578. S2CID 21026074.



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