WASF2

WASF2
Нинди таксонда бар H. sapiens[1]
Кодлаучы ген WASF2[d][1]
Молекуляр функция protein-containing complex binding[d][2][3], связывание с белками плазмы[d][4][5][6][…], actin binding[d][7][8][8], SH3 domain binding[d][9], cadherin binding[d][10], protein kinase A binding[d][11] һәм cadherin binding[d][12]
Күзәнәк компоненты цитоплазма[8], цитозоль[d][8], cell projection[d][8], SCAR complex[d][13], cell-cell junction[d][8], ruffle[d][8], внутренний компонент клетки[d][14], early endosome[d][8], actin cytoskeleton[d][7], экзосома[d][15][16], цитоскелет[d][8][8], lamellipodium[d][8][8][17], protein-containing complex[d][11], синапс[8] һәм экзосома[d][18][19]
Биологик процесс megakaryocyte development[d][8], эндоцитоз[d][8], Fc-gamma receptor signaling pathway involved in phagocytosis[d][8], adenylate cyclase-modulating G protein-coupled receptor signaling pathway[d][20], actin filament-based movement[d][8], vascular endothelial growth factor receptor signaling pathway[d][8], Ангиогенез[d][8], Rac protein signal transduction[d][8], вирусный процесс[d][8], positive regulation of lamellipodium assembly[d][13][4], negative regulation of stress fiber assembly[d][13], ameboidal-type cell migration[d][8], lamellipodium morphogenesis[d][8], actin cytoskeleton organization[d][20][8][8], lamellipodium assembly[d][8] һәм postsynaptic actin cytoskeleton organization[d][8]

WASF2 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[21][22]

Искәрмәләр

  1. ↑ 1,0 1,1 UniProt
  2. ↑ Otwinowski Z., Padrick S. B., Borek D. et al. Structure and control of the actin regulatory WAVE complex // Nature / M. Skipper — NPG, Springer Science+Business Media, 2010. — ISSN 1476-4687; 0028-0836 — doi:10.1038/NATURE09623 — PMID:21107423
  3. ↑ Houdusse A., Martin D., Gautreau A. et al. Free Brick1 is a trimeric precursor in the assembly of a functional wave complex // PLOS ONE / PLOS ONE Editors — PLoS, 2008. — ISSN 1932-6203 — doi:10.1371/JOURNAL.PONE.0002462 — PMID:18560548
  4. ↑ 4,0 4,1 Houdusse A., Martin D., Gautreau A. et al. Free Brick1 is a trimeric precursor in the assembly of a functional wave complex // PLOS ONE / PLOS ONE Editors — PLoS, 2008. — ISSN 1932-6203 — doi:10.1371/JOURNAL.PONE.0002462 — PMID:18560548
  5. ↑ Cantley L. C., Weiner O. D., Gygi S. P. et al. Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis // PLoS Biol. — PLoS, 2006. — ISSN 1544-9173; 1545-7885 — doi:10.1371/JOURNAL.PBIO.0040038 — PMID:16417406
  6. ↑ Butland S., David Tse Shen Lin, Singaraja R. et al. The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease // Human Molecular Genetics — OUP, 2014. — ISSN 0964-6906; 1460-2083 — doi:10.1093/HMG/DDU137 — PMID:24705354
  7. ↑ 7,0 7,1 Alto N. M. Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffold // EMBO J. — NPG, 2000. — ISSN 0261-4189; 1460-2075 — doi:10.1093/EMBOJ/19.17.4589 — PMID:10970852
  8. ↑ 8,00 8,01 8,02 8,03 8,04 8,05 8,06 8,07 8,08 8,09 8,10 8,11 8,12 8,13 8,14 8,15 8,16 8,17 8,18 8,19 8,20 8,21 8,22 8,23 8,24 8,25 8,26 GOA
  9. ↑ Zucconi A., Scita G., Disanza A. et al. Requirements for F-BAR proteins TOCA-1 and TOCA-2 in actin dynamics and membrane trafficking during Caenorhabditis elegans oocyte growth and embryonic epidermal morphogenesis // PLOS Genetics — PLoS, 2009. — ISSN 1553-7390; 1553-7404 — doi:10.1371/JOURNAL.PGEN.1000675 — PMID:19798448
  10. ↑ Zanivan S., Zaidel-Bar R. E-cadherin interactome complexity and robustness resolved by quantitative proteomics // Sci. Signal. — AAAS, 2014. — ISSN 1945-0877; 1937-9145 — doi:10.1126/SCISIGNAL.2005473 — PMID:25468996
  11. ↑ 11,0 11,1 Marcel van der Heyden, Albert J.R. Heck, Scholten A. A systematic evaluation of protein kinase A-A-kinase anchoring protein interaction motifs // Biochemistry — ACS, 2014. — ISSN 0006-2960; 1520-4995; 1943-295X — doi:10.1021/BI500721A — PMID:25097019
  12. ↑ Zanivan S., Zaidel-Bar R. E-cadherin interactome complexity and robustness resolved by quantitative proteomics // Sci. Signal. — AAAS, 2014. — ISSN 1945-0877; 1937-9145 — doi:10.1126/SCISIGNAL.2005473 — PMID:25468996
  13. ↑ 13,0 13,1 13,2 Otwinowski Z., Padrick S. B., Borek D. et al. Structure and control of the actin regulatory WAVE complex // Nature / M. Skipper — NPG, Springer Science+Business Media, 2010. — ISSN 1476-4687; 0028-0836 — doi:10.1038/NATURE09623 — PMID:21107423
  14. ↑ Hirao N., Sato S., Gotoh T. et al. NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation // FEBS Letters — Elsevier, 2006. — ISSN 0014-5793; 1873-3468 — doi:10.1016/J.FEBSLET.2006.10.065 — PMID:17101133
  15. ↑ Buschow S. I., Stoorvogel W., Wauben M. MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis // Immunology & Cell Biology — Wiley, 2010. — ISSN 0818-9641; 1440-1711 — doi:10.1038/ICB.2010.64 — PMID:20458337
  16. ↑ Sinha A., Kislinger T. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine // Proteomics / L. Stimson — Wiley, 2013. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.201200561 — PMID:23533145
  17. ↑ Hirao N., Sato S., Gotoh T. et al. NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation // FEBS Letters — Elsevier, 2006. — ISSN 0014-5793; 1873-3468 — doi:10.1016/J.FEBSLET.2006.10.065 — PMID:17101133
  18. ↑ Buschow S. I., Stoorvogel W., Wauben M. MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis // Immunology & Cell Biology — Wiley, 2010. — ISSN 0818-9641; 1440-1711 — doi:10.1038/ICB.2010.64 — PMID:20458337
  19. ↑ Sinha A., Kislinger T. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine // Proteomics / L. Stimson — Wiley, 2013. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.201200561 — PMID:23533145
  20. ↑ 20,0 20,1 Bear J. E., Rawls J. F., Saxe C. L. SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development, SCAR, a WASP-related Protein, Isolated as a Suppressor of Receptor Defects in Late Dictyostelium Development // J. Cell Biol. / J. Nunnari — Rockefeller University Press, 1998. — ISSN 0021-9525; 1540-8140 — doi:10.1083/JCB.142.5.1325 — PMID:9732292
  21. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланган. 18 сентябрь, 2017 тикшерелгән.
  22. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)


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