UTRN

UTRN
Нинди таксонда бар H. sapiens[1]
Кодлаучы ген UTRN[d][1]
Молекуляр функция vinculin binding[d][2], zinc ion binding[d][3], связывание с ионом металла[d][3], integrin binding[d][2], actin filament binding[d][3], связывание с белками плазмы[d][4][5][6][…], actin binding[d][3][2] һәм protein kinase binding[d][2]
Күзәнәк компоненты цитоплазма[3][4], postsynaptic membrane[d][3], contractile ring[d][2], мембрана[d][7][3], filopodium[d][2], Конус роста[d][3], нервно-мышечный синапс[d][3], күзәнәк мембранасы[d][8][3][3], синапс[3][3], dystrophin-associated glycoprotein complex[d][3], нуклеоплазма[d][3], межклеточные контакты[d][3], cortical actin cytoskeleton[d][3], Сарколемма[d][3], экзосома[d][9], цитоскелет[d][8][3], filopodium membrane[d][2], protein-containing complex[d][10] һәм экзосома[d][11]
Биологик процесс сокращение[d][12], positive regulation of cell-matrix adhesion[d][4], мускул органы үсеше[d][12], neuromuscular junction development[d][3], regulation of sodium ion transmembrane transporter activity[d][13] һәм response to denervation involved in regulation of muscle adaptation[d][3]

UTRN (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[14][15]

Искәрмәләр

  1. ↑ 1,0 1,1 UniProt
  2. ↑ 2,0 2,1 2,2 2,3 2,4 2,5 2,6 Cerecedo D., Mondragón R., Cisneros B. et al. Role of dystrophins and utrophins in platelet adhesion process // Br. J. Haematol. — Wiley-Blackwell, Wiley, 2006. — ISSN 0007-1048; 1365-2141 — doi:10.1111/J.1365-2141.2006.06120.X — PMID:16803572
  3. ↑ 3,00 3,01 3,02 3,03 3,04 3,05 3,06 3,07 3,08 3,09 3,10 3,11 3,12 3,13 3,14 3,15 3,16 3,17 3,18 3,19 3,20 GOA
  4. ↑ 4,0 4,1 4,2 Gibson S. B., Marshall A. J. TAPP2 links phosphoinositide 3-kinase signaling to B-cell adhesion through interaction with the cytoskeletal protein utrophin: expression of a novel cell adhesion-promoting complex in B-cell leukemia // Blood — American Society of Hematology, Elsevier, 2009. — ISSN 0006-4971; 1528-0020 — doi:10.1182/BLOOD-2009-03-213058 — PMID:19786618
  5. ↑ Campbell K., Li Z. Interactions of intermediate filament protein synemin with dystrophin and utrophin // Biochem. Biophys. Res. Commun. — Academic Press, Elsevier, 2006. — ISSN 0006-291X; 1090-2104 — doi:10.1016/J.BBRC.2006.05.192 — PMID:16777071
  6. ↑ A Tommasi di Vignano, Zenzo G. D. Contribution of the different modules in the utrophin carboxy-terminal region to the formation and regulation of the DAP complex // FEBS Letters — Elsevier, 2000. — ISSN 0014-5793; 1873-3468 — doi:10.1016/S0014-5793(00)01400-9 — PMID:10767429
  7. ↑ Nguyen T. M., Le T. T., Blake D. J. et al. Utrophin, the autosomal homologue of dystrophin, is widely-expressed and membrane-associated in cultured cell lines // FEBS Letters — Elsevier, 1992. — 4 p. — ISSN 0014-5793; 1873-3468 — doi:10.1016/0014-5793(92)81174-K — PMID:1426262
  8. ↑ 8,0 8,1 Guo W. X., M. Nichol, Merlie J. P. Cloning and expression of full length mouse utrophin: the differential association of utrophin and dystrophin with AChR clusters // FEBS Letters — Elsevier, 1996. — ISSN 0014-5793; 1873-3468 — doi:10.1016/S0014-5793(96)01216-1 — PMID:8977119
  9. ↑ Pisitkun T., Tchapyjnikov D., Knepper M. A. Large-scale proteomics and phosphoproteomics of urinary exosomes // Journal of the American Society of Nephrology / J. Briggs — American Society of Nephrology, 2008. — ISSN 1046-6673; 1533-3450 — doi:10.1681/ASN.2008040406 — PMID:19056867
  10. ↑ Lyssand J. S., DeFino M. C., Tang X. et al. Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2008. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M801860200 — PMID:18468998
  11. ↑ Pisitkun T., Tchapyjnikov D., Knepper M. A. Large-scale proteomics and phosphoproteomics of urinary exosomes // Journal of the American Society of Nephrology / J. Briggs — American Society of Nephrology, 2008. — ISSN 1046-6673; 1533-3450 — doi:10.1681/ASN.2008040406 — PMID:19056867
  12. ↑ 12,0 12,1 Brown S., Metzinger L. Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy // Cell — Cell Press, Elsevier, 1997. — ISSN 0092-8674; 1097-4172 — doi:10.1016/S0092-8674(00)80532-2 — PMID:9288751
  13. ↑ Koenig X. Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart // PLOS ONE / PLOS ONE Editors — PLoS, 2011. — ISSN 1932-6203 — doi:10.1371/JOURNAL.PONE.0020300 — PMID:21677768
  14. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланган. 18 сентябрь, 2017 тикшерелгән.
  15. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)


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