TXNIP

TXNIP
Нинди таксонда бар H. sapiens[1]
Кодлаучы ген TXNIP[d][1]
Молекуляр функция enzyme inhibitor activity[d][2], связывание с белками плазмы[d][3][4][3][…] һәм ubiquitin protein ligase binding[d][5]
Күзәнәк компоненты цитоплазма[2][2][4], цитозоль[d][2], mitochondrial intermembrane space[d][2] һәм төш[2]
Биологик процесс cellular response to tumor cell[d][6], response to estradiol[d][2], negative regulation of catalytic activity[d][2], ДНК-зависимая регуляция транскрипции[d][7], protein import into nucleus[d][2], response to progesterone[d][2], response to mechanical stimulus[d][2], negative regulation of transcription by RNA polymerase II[d][2], response to glucose[d][2], response to oxidative stress[d][2], транскрипция, ДНК-зависимая[d][7], keratinocyte differentiation[d][4], response to calcium ion[d][2], negative regulation of cell division[d][6], regulation of cell population proliferation[d][2], positive regulation of apoptotic process[d][2], клеточный цикл[d][2], platelet-derived growth factor receptor signaling pathway[d][2], response to hydrogen peroxide[d][2] һәм передача сигнала[d][7]
 TXNIP Викиҗыентыкта

TXNIP (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[8][9]

Искәрмәләр

  1. ↑ 1,0 1,1 UniProt
  2. ↑ 2,00 2,01 2,02 2,03 2,04 2,05 2,06 2,07 2,08 2,09 2,10 2,11 2,12 2,13 2,14 2,15 2,16 2,17 2,18 2,19 GOA
  3. ↑ 3,0 3,1 Kim T. TXNIP interacts with hEcd to increase p53 stability and activity // Biochem. Biophys. Res. Commun. — Academic Press, Elsevier, 2013. — ISSN 0006-291X; 1090-2104 — doi:10.1016/J.BBRC.2013.07.036 — PMID:23880345
  4. ↑ 4,0 4,1 4,2 Champliaud M., Viel A., Baden H. P. The expression of vitamin D-upregulated protein 1 in skin and its interaction with sciellin in cultured keratinocytes // J. Invest. Dermatol. / M. C. Udey — NPG, Elsevier, 2003. — ISSN 0022-202X; 1523-1747 — doi:10.1046/J.1523-1747.2003.12539.X — PMID:14632196
  5. ↑ Zhang P., Wang C., Gao K. et al. The ubiquitin ligase itch regulates apoptosis by targeting thioredoxin-interacting protein for ubiquitin-dependent degradation // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2010. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M109.063321 — PMID:20068034
  6. ↑ 6,0 6,1 Shin K., Kim R. H., Kim R. H. et al. hnRNP G elicits tumor-suppressive activity in part by upregulating the expression of Txnip // Biochem. Biophys. Res. Commun. — Academic Press, Elsevier, 2008. — ISSN 0006-291X; 1090-2104 — doi:10.1016/J.BBRC.2008.05.175 — PMID:18541147
  7. ↑ 7,0 7,1 7,2 GOA
  8. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланган. 18 сентябрь, 2017 тикшерелгән.
  9. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)


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