RBM10

RBM10
Нинди таксонда бар H. sapiens[1]
Кодлаштыра RNA binding motif protein 10[d][2] һәм RNA binding motif protein 10, isoform CRA_d[d][2]
Генетик бәйләнеш TARP syndrome[d][2][3], почечноклеточный рак[d][4][5][6], колоректаль яманшеш[d][7][8][6], аденокарцинома лёгкого[d][9][10][6], bladder carcinoma[d][10][6], Низко-дифференцированный рак щитовидной железы[d][11][12][6], Холангиокарцинома[d][13][14][6], Менингиома[15][6], астробластома[d][16][6], сөт бизе яман шеше[17][6] һәм простата яман шеше[17][6]
Хромосома X-хромосома[d][1]
Ген ориентациясе уңай ориентация[d][1]
Геномик башлангыч 47004268[1] һәм 47145221[1]
Геномик ахыр 47186813[1] һәм 47046212[1]
Цитогенетик өлкә Xp11.3[18]
Homologene идентификаторы 31330[18]
Изображение Gene Atlas
Ортолог гены Rbm10[d][19][20], Rbm10[d][19][20], rbm10[d][19], CG4896[d][19] һәм CG4887[d][19][20]
Экпрессия урыны right hemisphere of cerebellum[d][21], ventricular zone[d][21], ганглионар кытыршы[d][21], Гранулоциты[d][21], левый яичник[d][21], tendon of biceps brachii[d][21], правый яичник[d][21], гипофиз[21], гипофизның алгы өлеше[d][21] һәм mucosa of transverse colon[d][21]

RBM10 (ингл. RNA binding motif protein 10[d][2] һәм RNA binding motif protein 10, isoform CRA_d[d][2]) — X-хромосома[d][1] аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[22][23]

Искәрмәләр

  1. ↑ 1,0 1,1 1,2 1,3 1,4 1,5 1,6 1,7 ensembl Release 106 — 106
  2. ↑ 2,0 2,1 2,2 2,3 2,4 UniProt
  3. ↑ Open Targets Platform
  4. ↑ Xia Q., Wang X., Zhan X. et al. Xp11 Translocation Renal Cell Carcinomas (RCCs) With RBM10-TFE3 Gene Fusion Demonstrating Melanotic Features and Overlapping Morphology With t(6;11) RCC: Interest and Diagnostic Pitfall in Detecting a Paracentric Inversion of TFE3. // Am. J. Surg. Pathol. — Lippincott Williams & Wilkins, 2017. — ISSN 0147-5185; 1532-0979 — doi:10.1097/PAS.0000000000000837 — PMID:28288037
  5. ↑ Kato I., Furuya M., Baba M. et al. RBM10-TFE3 renal cell carcinoma characterised by paracentric inversion with consistent closely split signals in break-apart fluorescence in-situ hybridisation: study of 10 cases and a literature review // Histopathology — Wiley-Blackwell, Wiley, 2019. — ISSN 0309-0167; 1365-2559 — doi:10.1111/HIS.13866 — PMID:30908700
  6. ↑ 6,00 6,01 6,02 6,03 6,04 6,05 6,06 6,07 6,08 6,09 Inoue A. RBM10: Structure, functions, and associated diseases // Gene — Elsevier, 2021. — ISSN 0378-1119; 1879-0038 — doi:10.1016/J.GENE.2021.145463 — PMID:33515724
  7. ↑ Lander E., Getz G., Stojanov P. et al. Discovery and saturation analysis of cancer genes across 21 tumour types // Nature / M. Skipper — NPG, Springer Science+Business Media, 2014. — ISSN 1476-4687; 0028-0836 — doi:10.1038/NATURE12912 — PMID:24390350
  8. ↑ Getz G., Lander E. S., Rosenberg M. et al. Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma // Cell Reports — Cell Press, Elsevier, 2016. — ISSN 2211-1247; 2639-1856 — doi:10.1016/J.CELREP.2016.03.075 — PMID:27149842
  9. ↑ Lander E., Cibulskis K., Auclair D. et al. Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing // Cell — Cell Press, Elsevier, 2012. — ISSN 0092-8674; 1097-4172 — doi:10.1016/J.CELL.2012.08.029 — PMID:22980975
  10. ↑ 10,0 10,1 Cancer Genome Atlas Research Network, Carvalho A. C. d. Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types // Cell Reports — Cell Press, Elsevier, 2018. — ISSN 2211-1247; 2639-1856 — doi:10.1016/J.CELREP.2018.01.088 — PMID:29617667
  11. ↑ Xu B., Middha S. Genomic Alterations in Fatal Forms of Non-Anaplastic Thyroid Cancer: Identification of MED12 and RBM10 as Novel Thyroid Cancer Genes Associated with Tumor Virulence // Clin. Cancer Res. / K. Flaherty — American Association for Cancer Research, 2017. — ISSN 1078-0432; 1557-3265 — doi:10.1158/1078-0432.CCR-17-1183 — PMID:28634282
  12. ↑ Ibrahimpasic T., Ghossein R., Shah J. P. et al. Poorly Differentiated Carcinoma of the Thyroid Gland: Current Status and Future Prospects // Thyroid — Mary Ann Liebert, Inc., 2019. — ISSN 1050-7256; 1557-9077 — doi:10.1089/THY.2018.0509 — PMID:30747050
  13. ↑ Tian W., Hu W., Shi X. et al. Comprehensive genomic profile of cholangiocarcinomas in China // Oncology Letters / D. Spandidos — 2020. — ISSN 1792-1074; 1792-1082 — doi:10.3892/OL.2020.11429 — PMID:32256810
  14. ↑ Schwab M. E., Song H., Mattis A. et al. De novo somatic mutations and KRAS amplification are associated with cholangiocarcinoma in a patient with a history of choledochal cyst // Journal of Pediatric Surgery — Elsevier, 2020. — ISSN 0022-3468; 1531-5037 — doi:10.1016/J.JPEDSURG.2020.03.008 — PMID:32295706
  15. ↑ (not translated to en), McCabe D., Williams E. et al. DMD genomic deletions characterize a subset of progressive/higher-grade meningiomas with poor outcome // Acta Neuropathol. (Berl) — Springer Science+Business Media, 2018. — ISSN 0001-6322; 1432-0533 — doi:10.1007/S00401-018-1899-7 — PMID:30123936
  16. ↑ Majd N. K., Metrus N. R., Santos-Pinheiro F. et al. RBM10 truncation in astroblastoma in a patient with history of mandibular ameloblastoma: A case report // Cancer Genetics — Elsevier, 2019. — ISSN 2210-7762; 2210-7770 — doi:10.1016/J.CANCERGEN.2019.01.001 — PMID:30803556
  17. ↑ 17,0 17,1 Bourgon R., Peters B. A., Modrusan Z. et al. Diverse somatic mutation patterns and pathway alterations in human cancers // Nature / M. Skipper — NPG, Springer Science+Business Media, 2010. — ISSN 1476-4687; 0028-0836 — doi:10.1038/NATURE09208 — PMID:20668451
  18. ↑ 18,0 18,1 NCBI Gene
  19. ↑ 19,0 19,1 19,2 19,3 19,4 HomoloGene сборка 68 — 68 — 2014.
  20. ↑ 20,0 20,1 20,2 Orthologous MAtrix
  21. ↑ 21,00 21,01 21,02 21,03 21,04 21,05 21,06 21,07 21,08 21,09 Bgee
  22. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланган. 18 сентябрь, 2017 тикшерелгән.
  23. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.