PNLIP

PNLIP
Рәвеш
Нинди таксонда бар H. sapiens[1]
Кодлаучы ген Панкреатическая липаза[d][1]
Молекуляр функция triglyceride lipase activity[d][2][3][3][…], carboxylic ester hydrolase activity[d][3], гидролазная активность[d][3], связывание с ионом металла[d][3], lipase activity[d][4], связывание с белками плазмы[d][5][6], triglyceride lipase activity[d][2][3][3][…] һәм lipase activity[d][4][7]
Күзәнәк компоненты күзәнәк тышындагы өлкә[d][3][3], күзәнәк тышындагы мохит[d][4] һәм күзәнәк тышындагы мохит[d][4][7]
Биологик процесс lipid catabolic process[d][3], positive regulation of triglyceride lipase activity[d][8], intestinal cholesterol absorption[d][3], липидный обмен[d][9][3][3], retinoid metabolic process[d][3], lipid digestion[d][3] һәм lipid catabolic process[d][3][7]
Тәэсир итешә орлистат[d][10]
Шифр КФ 3.1.1.3
 PNLIP Викиҗыентыкта

PNLIP (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[11][12]

Искәрмәләр

  1. ↑ 1,0 1,1 UniProt
  2. ↑ 2,0 2,1 Davis R. C., A. Diep, W. Hunziker et al. Assignment of human pancreatic lipase gene (PNLIP) to chromosome 10q24-q26, Assignment of human pancreatic lipase gene (PNLIP) to chromosome 10q24–q26 // Genomics / A. Engel — Academic Press, Elsevier, 1991. — ISSN 0888-7543; 1089-8646 — doi:10.1016/0888-7543(91)90048-J — PMID:1783385
  3. ↑ 3,00 3,01 3,02 3,03 3,04 3,05 3,06 3,07 3,08 3,09 3,10 3,11 3,12 3,13 3,14 3,15 GOA
  4. ↑ 4,0 4,1 4,2 4,3 Sahin-Tóth M. A novel mutation in PNLIP causes pancreatic triglyceride lipase deficiency through protein misfolding // Biochim. Biophys. Acta — Elsevier, 2015. — ISSN 0006-3002; 1878-2434 — doi:10.1016/J.BBADIS.2015.04.002 — PMID:25862608
  5. ↑ Egloff M. P., F Marguet, G Buono et al. The 2.46 A resolution structure of the pancreatic lipase-colipase complex inhibited by a C11 alkyl phosphonate // Biochemistry — ACS, 1995. — ISSN 0006-2960; 1520-4995; 1943-295X — doi:10.1021/BI00009A003 — PMID:7893686
  6. ↑ Tilbeurgh H. v., L Sarda, R Verger et al. Structure of the pancreatic lipase-procolipase complex // Nature / M. Skipper — NPG, Springer Science+Business Media, 1992. — ISSN 1476-4687; 0028-0836 — doi:10.1038/359159A0 — PMID:1522902
  7. ↑ 7,0 7,1 7,2 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
  8. ↑ Y. Yang, Lowe M. E. Human pancreatic triglyceride lipase expressed in yeast cells: purification and characterization, Human Pancreatic Triglyceride Lipase Expressed in Yeast Cells: Purification and Characterization // PREP — Elsevier, 1998. — ISSN 1046-5928; 1096-0279 — doi:10.1006/PREP.1998.0874 — PMID:9631512
  9. ↑ Basel-Vanagaite L., Behar D. M., Tzur S. et al. Identification of a novel mutation in the PNLIP gene in two brothers with congenital pancreatic lipase deficiency // J. Lipid Res. — American Society for Biochemistry and Molecular Biology, 2013. — ISSN 0022-2275; 1539-7262 — doi:10.1194/JLR.P041103 — PMID:24262094
  10. ↑ IUPHAR/BPS Guide to PHARMACOLOGY
  11. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланган. 18 сентябрь, 2017 тикшерелгән.
  12. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.