FGF18

FGF18
Нинди таксонда бар H. sapiens[1]
Кодлаучы ген FGF18[d][1]
Молекуляр функция fibroblast growth factor receptor binding[d][2], type 1 fibroblast growth factor receptor binding[d][3], type 2 fibroblast growth factor receptor binding[d][3], growth factor activity[d][4][2][2], protein tyrosine kinase activity[d][5], phosphatidylinositol-4,5-bisphosphate 3-kinase activity[d][5] һәм 1-phosphatidylinositol-3-kinase activity[d][5]
Күзәнәк компоненты күзәнәк тышындагы өлкә[d][2][2][2], ядрышко[d][2] һәм күзәнәк тышындагы мохит[d][4]
Биологик процесс intramembranous ossification[d][2], positive regulation of vascular endothelial growth factor receptor signaling pathway[d][2], regulation of sprouting angiogenesis[d][6], positive regulation of endothelial cell chemotaxis to fibroblast growth factor[d][6], positive regulation of MAP kinase activity[d][6], оссификация[d][2], үпкәләр үсеше[d][2], передача сигнала между клетками[d][4], морфогенез анатомической структуры[d][4], chondrocyte development[d][2], endochondral ossification[d][2], MAPK cascade[d][2], fibroblast growth factor receptor signaling pathway[d][2][2][2], positive regulation of chondrocyte differentiation[d][2], Ангиогенез[d][2], позитивная регуляция пролиферации клеток[d][4][2], regulation of endothelial cell proliferation[d][6], передача сигнала[d][4], phosphatidylinositol phosphate biosynthetic process[d][5], peptidyl-tyrosine phosphorylation[d][5], phosphatidylinositol-3-phosphate biosynthetic process[d][5], regulation of signaling receptor activity[d][2], позитивная регуляция сигналов от протеинкиназы В[d][2], positive regulation of blood vessel endothelial cell migration[d][7], positive regulation of angiogenesis[d][7] һәм positive regulation of ERK1 and ERK2 cascade[d][2]

FGF18 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[8][9]

Искәрмәләр

  1. 1,0 1,1 UniProt
  2. 2,00 2,01 2,02 2,03 2,04 2,05 2,06 2,07 2,08 2,09 2,10 2,11 2,12 2,13 2,14 2,15 2,16 2,17 2,18 2,19 2,20 2,21 2,22 GOA
  3. 3,0 3,1 Mohammadi M., Olsen S. K., Linhardt R. J. Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain // Genes Dev.Cold Spring Harbor Laboratory Press, 2005. — ISSN 0890-9369; 1549-5477doi:10.1101/GAD.1365406PMID:16384934
  4. 4,0 4,1 4,2 4,3 4,4 4,5 M. DeRose, R. Luethy, Danilenko D. M. FGF-18, a novel member of the fibroblast growth factor family, stimulates hepatic and intestinal proliferation, FGF-18, a Novel Member of the Fibroblast Growth Factor Family, Stimulates Hepatic and Intestinal Proliferation // Mol. Cell. Biol.ASM, 1998. — ISSN 0270-7306; 1098-5549; 1067-8824doi:10.1128/MCB.18.10.6063PMID:9742123
  5. 5,0 5,1 5,2 5,3 5,4 5,5 GOA
  6. 6,0 6,1 6,2 6,3 M Antoine, W Wirz, Tag C. G. et al. Fibroblast growth factor 16 and 18 are expressed in human cardiovascular tissues and induce on endothelial cells migration but not proliferation // Biochem. Biophys. Res. Commun.Academic Press, Elsevier, 2006. — ISSN 0006-291X; 1090-2104doi:10.1016/J.BBRC.2006.05.105PMID:16756958
  7. 7,0 7,1 Wu Q. MicroRNA-505 identified from patients with essential hypertension impairs endothelial cell migration and tube formation // Int. J. Cardiol. / Andrew Justin Stewart CoatsElsevier, 2014. — ISSN 0167-5273; 1874-1754doi:10.1016/J.IJCARD.2014.09.204PMID:25449503
  8. HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланган. 18 сентябрь, 2017 тикшерелгән.
  9. UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)

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