DLX4

DLX4
Нинди таксонда бар H. sapiens[1]
Кодлаучы ген DLX4[d][1]
Молекуляр функция ДНК-связывающий[d][2][2], связывание с белками плазмы[d][3][4], RNA polymerase II cis-regulatory region sequence-specific DNA binding[d][5], DNA-binding transcription repressor activity, RNA polymerase II-specific[d][5][6], DNA-binding transcription factor activity[d][7][8], sequence-specific DNA binding[d][9][10], DNA-binding transcription factor activity, RNA polymerase II-specific[d][11][11][2], RNA polymerase II cis-regulatory region sequence-specific DNA binding[d][6][12], DNA-binding transcription factor activity[d][13][14][12] һәм sequence-specific DNA binding[d][2][15][12]
Күзәнәк компоненты төш[8][9] һәм төш[14][2][12]
Биологик процесс развитие многоклеточного организма[d][2], negative regulation of transcription by RNA polymerase II[d][5], ДНК-зависимая регуляция транскрипции[d][14][2], negative regulation of transcription by RNA polymerase II[d][6][12] һәм regulation of transcription by RNA polymerase II[d][12]

DLX4 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[16][17]

Искәрмәләр

  1. ↑ 1,0 1,1 UniProt
  2. ↑ 2,0 2,1 2,2 2,3 2,4 2,5 2,6 GOA
  3. ↑ Geisler M., Jurisica I. Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening // Proteomics / L. Stimson — Wiley, 2007. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.200601006 — PMID:17474147
  4. ↑ Trinh B. Q., N. Barengo, H. Naora Homeodomain protein DLX4 counteracts key transcriptional control mechanisms of the TGF-β cytostatic program and blocks the antiproliferative effect of TGF-β // Oncogene — NPG, 2011. — ISSN 0950-9232; 1476-5594 — doi:10.1038/ONC.2011.4 — PMID:21297662
  5. ↑ 5,0 5,1 5,2 Chase M. B., Fu S., Haga S. B. et al. BP1, a homeodomain-containing isoform of DLX4, represses the beta-globin gene // Mol. Cell. Biol. — ASM, 2002. — ISSN 0270-7306; 1098-5549; 1067-8824 — doi:10.1128/MCB.22.8.2505-2514.2002 — PMID:11909945
  6. ↑ 6,0 6,1 6,2 Chase M. B., Fu S., Haga S. B. et al. BP1, a homeodomain-containing isoform of DLX4, represses the beta-globin gene // Mol. Cell. Biol. — ASM, 2002. — ISSN 0270-7306; 1098-5549; 1067-8824 — doi:10.1128/MCB.22.8.2505-2514.2002 — PMID:11909945
  7. ↑ S. Nakamura, Stock D. W., Wydner K. L. et al. Genomic analysis of a new mammalian distal-less gene: Dlx7 // Genomics / A. Engel — Academic Press, Elsevier, 1996. — ISSN 0888-7543; 1089-8646 — doi:10.1006/GENO.1996.0634 — PMID:8975708
  8. ↑ 8,0 8,1 Ruscetti F. W. BP1, a new homeobox gene, is frequently expressed in acute leukemias // Leukemia — NPG, 2000. — ISSN 0887-6924; 1476-5551 — doi:10.1038/SJ.LEU.2401912 — PMID:11069021
  9. ↑ 9,0 9,1 GOA
  10. ↑ Quinn L. M., Johnson B. V., J Nicholl et al. Isolation and identification of homeobox genes from the human placenta including a novel member of the Distal-less family, DLX4 // Gene — Elsevier, 1997. — ISSN 0378-1119; 1879-0038 — doi:10.1016/S0378-1119(96)00706-8 — PMID:9073066
  11. ↑ 11,0 11,1 Vaquerizas J. M., Teichmann S., Kummerfeld S. K. A census of human transcription factors: function, expression and evolution // Nature reviews. Genetics — United Kingdom: NPG, 2009. — ISSN 1471-0056; 1471-0064 — doi:10.1038/NRG2538 — PMID:19274049
  12. ↑ 12,0 12,1 12,2 12,3 12,4 12,5 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
  13. ↑ S. Nakamura, Stock D. W., Wydner K. L. et al. Genomic analysis of a new mammalian distal-less gene: Dlx7 // Genomics / A. Engel — Academic Press, Elsevier, 1996. — ISSN 0888-7543; 1089-8646 — doi:10.1006/GENO.1996.0634 — PMID:8975708
  14. ↑ 14,0 14,1 14,2 Ruscetti F. W. BP1, a new homeobox gene, is frequently expressed in acute leukemias // Leukemia — NPG, 2000. — ISSN 0887-6924; 1476-5551 — doi:10.1038/SJ.LEU.2401912 — PMID:11069021
  15. ↑ Quinn L. M., Johnson B. V., J Nicholl et al. Isolation and identification of homeobox genes from the human placenta including a novel member of the Distal-less family, DLX4 // Gene — Elsevier, 1997. — ISSN 0378-1119; 1879-0038 — doi:10.1016/S0378-1119(96)00706-8 — PMID:9073066
  16. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланган. 18 сентябрь, 2017 тикшерелгән.
  17. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.