Complement receptor 2

Complement receptor 2
Нинди таксонда бар H. sapiens[1]
Кодлаучы ген Рецептор комплемента 2-го типа[d][1]
Молекуляр функция ДНК-связывающий[d][2], гомодимеризация белка[d][3], virus receptor activity[d][4], complement binding[d][5], transmembrane signaling receptor activity[d][6], complement receptor activity[d][7][6] һәм связывание с белками плазмы[d][8]
Күзәнәк компоненты мембрана өлеше[d][6][4], мембрана[d][4], receptor complex[d][9], экзосома[d][10], күзәнәк мембранасы[d][11][12], экзосома[d][13] һәм күзәнәк мембранасы[d][4][7][4]
Биологик процесс процесс иммунной системы[d][4], B cell proliferation[d][14], иммун җавап[d][6], Классический путь активации системы комплемента[d][4], viral entry into host cell[d][4], B cell differentiation[d][14], врождённый иммунитет[d][4], вирусный процесс[d][4], complement receptor mediated signaling pathway[d][4], передача сигнала[d][11] һәм regulation of complement activation[d][4]
Изображение Gene Atlas

Complement receptor 2 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[15][16]

Искәрмәләр

  1. ↑ 1,0 1,1 UniProt
  2. ↑ Holers V. M., Szakonyi G., Asokan R. Human complement receptor 2 (CR2/CD21) as a receptor for DNA: implications for its roles in the immune response and the pathogenesis of systemic lupus erythematosus (SLE), Human complement receptor 2 (CR2/CD21) as a receptor for DNA: Implications for its roles in the immune response and the pathogenesis of systemic lupus erythematosus (SLE) // Molecular Immunology — Elsevier, 2013. — 12 p. — ISSN 0161-5890; 1872-9142 — doi:10.1016/J.MOLIMM.2012.07.002 — PMID:22885687
  3. ↑ Holers V. M., Boackle S. A. Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein, Cr2, a Candidate Gene in the Murine Sle1c Lupus Susceptibility Locus, Encodes a Dysfunctional Protein // Immunity — Cell Press, Elsevier, 2001. — ISSN 1074-7613; 1097-4180 — doi:10.1016/S1074-7613(01)00228-X — PMID:11728339
  4. ↑ 4,00 4,01 4,02 4,03 4,04 4,05 4,06 4,07 4,08 4,09 4,10 4,11 GOA
  5. ↑ L Clemenza, Isenman D. E. Structure-guided identification of C3d residues essential for its binding to complement receptor 2 (CD21) // J. Immunol. — Baltimore: 2000. — ISSN 0022-1767; 1550-6606 — doi:10.4049/JIMMUNOL.165.7.3839 — PMID:11034390
  6. ↑ 6,0 6,1 6,2 6,3 Moore M. D., Cooper N. R., Tack B. F. et al. Molecular cloning of the cDNA encoding the Epstein-Barr virus/C3d receptor (complement receptor type 2) of human B lymphocytes // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 1987. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.84.24.9194 — PMID:2827171
  7. ↑ 7,0 7,1 Harley J. B., Holers V. M. Genomic organization and polymorphisms of the human C3d/Epstein-Barr virus receptor // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1989. — ISSN 0021-9258; 1083-351X; 1067-8816 — PMID:2563370
  8. ↑ M Barel, M Balbo, A Gauffre et al. Binding sites of the Epstein-Barr virus and C3d receptor (CR2, CD21) for its three intracellular ligands, the p53 anti-oncoprotein, the p68 calcium binding protein and the nuclear p120 ribonucleoprotein // Molecular Immunology — Elsevier, 1995. — ISSN 0161-5890; 1872-9142 — doi:10.1016/0161-5890(95)00005-Y — PMID:7753047
  9. ↑ Ghai R., Coulson E. J., Collins B. M. et al. Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 2013. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.1216229110 — PMID:23382219
  10. ↑ Buschow S. I., Stoorvogel W., Wauben M. MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis // Immunology & Cell Biology — Wiley, 2010. — ISSN 0818-9641; 1440-1711 — doi:10.1038/ICB.2010.64 — PMID:20458337
  11. ↑ 11,0 11,1 GOA
  12. ↑ Harley J. B., Holers V. M. Genomic organization and polymorphisms of the human C3d/Epstein-Barr virus receptor // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1989. — ISSN 0021-9258; 1083-351X; 1067-8816 — PMID:2563370
  13. ↑ Buschow S. I., Stoorvogel W., Wauben M. MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis // Immunology & Cell Biology — Wiley, 2010. — ISSN 0818-9641; 1440-1711 — doi:10.1038/ICB.2010.64 — PMID:20458337
  14. ↑ 14,0 14,1 GR N., ME M., NR C. Binding of monoclonal antibody to the Epstein Barr virus (EBV)/CR2 receptor induces activation and differentiation of human B lymphocytes // J. Immunol. — Baltimore: 1985. — ISSN 0022-1767; 1550-6606 — PMID:2995485
  15. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланган. 18 сентябрь, 2017 тикшерелгән.
  16. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)


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