COL15A1

COL15A1
Нинди таксонда бар H. sapiens[1]
Кодлаучы ген COL15A1[d][1]
Молекуляр функция extracellular matrix structural constituent[d][2], structural molecule activity[d][3], extracellular matrix structural constituent[d][4], extracellular matrix structural constituent conferring tensile strength[d][5][6][7][…], extracellular matrix structural constituent conferring tensile strength[d][8][9][10][…] һәм extracellular matrix structural constituent conferring tensile strength[d][9][11][8][…]
Күзәнәк компоненты мембрана өлеше[d][12], базаль мембрана[d][3][3], коллаген[d][3], endoplasmic reticulum lumen[d][3], экзосома[d][13][14][15], collagen type XV trimer[d][16], күзәнәк тышындагы өлкә[d][3][3], внеклеточный матрикс[d][17][5][18][…], күзәнәк тышындагы мохит[d][5][6], күзәнәк тышындагы мохит[d][4][8], внеклеточный матрикс[d][4], collagen-containing extracellular matrix[d][19][9][11][…] һәм экзосома[d][20][21]
Биологик процесс collagen catabolic process[d][3], развитие многоклеточного организма[d][3], дифференцировка клеток[d][3], Ангиогенез[d][3], передача сигнала[d][12], агрегация клеток[d][5][5][2], агрегация клеток[d][3][3] һәм extracellular matrix organization[d][4]
Тәэсир итешә ocriplasmin[d][22]

COL15A1 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[23][24]

Искәрмәләр

  1. ↑ 1,0 1,1 UniProt
  2. ↑ 2,0 2,1 T. Pihlajaniemi Complete exon-intron organization of the human gene for the alpha1 chain of type XV collagen (COL15A1) and comparison with the homologous COL18A1 gene, Complete Exon-Intron Organization of the Human Gene for the α1 Chain of Type XV Collagen (COL15A1) and Comparison with the Homologous Col18a1 Gene // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1998. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.273.28.17824 — PMID:9651385
  3. ↑ 3,00 3,01 3,02 3,03 3,04 3,05 3,06 3,07 3,08 3,09 3,10 3,11 3,12 GOA
  4. ↑ 4,0 4,1 4,2 4,3 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
  5. ↑ 5,0 5,1 5,2 5,3 5,4 GOA
  6. ↑ 6,0 6,1 Didangelos A., Yin X., Mayr M. Proteomics characterization of extracellular space components in the human aorta // Mol. Cell. Proteomics — American Society for Biochemistry and Molecular Biology, 2010. — ISSN 1535-9476; 1535-9484 — doi:10.1074/MCP.M110.001693 — PMID:20551380
  7. ↑ Yin X., Mayr M., Porter K. E. Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins // Cardiovascular Research — OUP, 2016. — ISSN 0008-6363; 1755-3245 — doi:10.1093/CVR/CVW075 — PMID:27068509
  8. ↑ 8,0 8,1 8,2 Didangelos A., Yin X., Mayr M. Proteomics characterization of extracellular space components in the human aorta // Mol. Cell. Proteomics — American Society for Biochemistry and Molecular Biology, 2010. — ISSN 1535-9476; 1535-9484 — doi:10.1074/MCP.M110.001693 — PMID:20551380
  9. ↑ 9,0 9,1 9,2 Naba A., Oliver M T Pearce, Hynes R. O. Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics // J. Proteome Res. / J. Yates — ACS, 2017. — ISSN 1535-3893; 1535-3907 — doi:10.1021/ACS.JPROTEOME.7B00191 — PMID:28675934
  10. ↑ Naba A., Clauser K. R., Hynes R. O. Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver // BMC Cancer — BMC, Springer Science+Business Media, 2014. — ISSN 1471-2407 — doi:10.1186/1471-2407-14-518 — PMID:25037231
  11. ↑ 11,0 11,1 Yin X., Mayr M., Porter K. E. Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins // Cardiovascular Research — OUP, 2016. — ISSN 0008-6363; 1755-3245 — doi:10.1093/CVR/CVW075 — PMID:27068509
  12. ↑ 12,0 12,1 H Takeshima Characterization of human junctophilin subtype genes // Biochem. Biophys. Res. Commun. — Academic Press, Elsevier, 2000. — ISSN 0006-291X; 1090-2104 — doi:10.1006/BBRC.2000.3011 — PMID:10891348
  13. ↑ Pisitkun T., Tchapyjnikov D., Knepper M. A. Large-scale proteomics and phosphoproteomics of urinary exosomes // Journal of the American Society of Nephrology / J. Briggs — American Society of Nephrology, 2008. — ISSN 1046-6673; 1533-3450 — doi:10.1681/ASN.2008040406 — PMID:19056867
  14. ↑ Sinha A., Kislinger T. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine // Proteomics / L. Stimson — Wiley, 2013. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.201200561 — PMID:23533145
  15. ↑ Farina A., Lane L., Lescuyer P. et al. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine // Journal of Proteomics — Elsevier, 2013. — ISSN 1874-3919; 0165-022X — doi:10.1016/J.JPROT.2013.01.012 — PMID:23376485
  16. ↑ T. Pihlajaniemi Complete exon-intron organization of the human gene for the alpha1 chain of type XV collagen (COL15A1) and comparison with the homologous COL18A1 gene, Complete Exon-Intron Organization of the Human Gene for the α1 Chain of Type XV Collagen (COL15A1) and Comparison with the Homologous Col18a1 Gene // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1998. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.273.28.17824 — PMID:9651385
  17. ↑ Didangelos A., Doménech N., Willeit P. et al. Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury // Circulation — Lippincott Williams & Wilkins, 2012. — ISSN 0009-7322; 1524-4539 — doi:10.1161/CIRCULATIONAHA.111.056952 — PMID:22261194
  18. ↑ Mayr M., Iozzo R. V., Barallobre-Barreiro J. et al. Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation // Circulation — Lippincott Williams & Wilkins, 2016. — ISSN 0009-7322; 1524-4539 — doi:10.1161/CIRCULATIONAHA.115.016423 — PMID:27559042
  19. ↑ Didangelos A., Doménech N., Willeit P. et al. Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury // Circulation — Lippincott Williams & Wilkins, 2012. — ISSN 0009-7322; 1524-4539 — doi:10.1161/CIRCULATIONAHA.111.056952 — PMID:22261194
  20. ↑ Pisitkun T., Tchapyjnikov D., Knepper M. A. Large-scale proteomics and phosphoproteomics of urinary exosomes // Journal of the American Society of Nephrology / J. Briggs — American Society of Nephrology, 2008. — ISSN 1046-6673; 1533-3450 — doi:10.1681/ASN.2008040406 — PMID:19056867
  21. ↑ Sinha A., Kislinger T. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine // Proteomics / L. Stimson — Wiley, 2013. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.201200561 — PMID:23533145
  22. ↑ Open Targets Platform
  23. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланган. 18 сентябрь, 2017 тикшерелгән.
  24. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)

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