CD59

CD59
Нинди таксонда бар H. sapiens[1]
Кодлаучы ген CD59[d][1]
Молекуляр функция связывание с белками плазмы[d][2][3], complement binding[d][4][4] һәм complement binding[d][5]
Күзәнәк компоненты везикула[d][6], endoplasmic reticulum membrane[d][7], мембрана[d][8][7], фокальные контакты[d][9], Golgi membrane[d][7], күзәнәк мембранасы[d][4][10][4][…], күзәнәк тышындагы өлкә[d][7], күзәнәк өслеге[d][11], compact myelin[d][4], anchored component of external side of plasma membrane[d][12], ER to Golgi transport vesicle membrane[d][7], anchored component of membrane[d][7], Сарколемма[d][4], экзосома[d][13][14][15][…], endoplasmic reticulum-Golgi intermediate compartment membrane[d][7], күзәнәк тышындагы мохит[d][4][16], specific granule membrane[d][7], tertiary granule membrane[d][7], transport vesicle[d][7], күзәнәк тышындагы мохит[d][17], күзәнәк мембранасы[d][7][8][7][…], фокальные контакты[d][18], күзәнәк өслеге[d][19][5], везикула[d][20] һәм экзосома[d][21][22][23][…]
Биологик процесс cвёртывание крови[d][8], негативная регуляция апоптоза[d][4], negative regulation of activation of membrane attack complex[d][7], endoplasmic reticulum to Golgi vesicle-mediated transport[d][7], cell surface receptor signaling pathway[d][24], COPII vesicle coating[d][7], positive regulation of T cell proliferation[d][4], regulation of complement activation[d][4][4], cell activation[d][4], neutrophil degranulation[d][7], regulation of complement activation[d][7], regulation of complement activation[d][7][25], regulation of complement-dependent cytotoxicity[d][25] һәм negative regulation of activation of membrane attack complex[d][7][5]
Изображение Gene Atlas
 CD59 Викиҗыентыкта

CD59 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[26][27]

Искәрмәләр

  1. ↑ 1,0 1,1 UniProt
  2. ↑ Ni B. Hepatitis B virus core protein interacts with CD59 to promote complement-mediated liver inflammation during chronic hepatitis B virus infection // FEBS Letters — Elsevier, 2013. — ISSN 0014-5793; 1873-3468 — doi:10.1016/J.FEBSLET.2013.08.044 — PMID:24036449
  3. ↑ Bonnon C., Wendeler M. W., Paccaud J. et al. Selective export of human GPI-anchored proteins from the endoplasmic reticulum // J. Cell Sci. — The Company of Biologists, 2010. — ISSN 0021-9533; 1477-9137 — doi:10.1242/JCS.062950 — PMID:20427317
  4. ↑ 4,00 4,01 4,02 4,03 4,04 4,05 4,06 4,07 4,08 4,09 4,10 4,11 GOA
  5. ↑ 5,0 5,1 5,2 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
  6. ↑ Pickles R. J. Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense // FASEB J. — FASEB, 2009. — ISSN 0892-6638; 1530-6860 — doi:10.1096/FJ.08-119131 — PMID:19190083
  7. ↑ 7,00 7,01 7,02 7,03 7,04 7,05 7,06 7,07 7,08 7,09 7,10 7,11 7,12 7,13 7,14 7,15 7,16 7,17 7,18 GOA
  8. ↑ 8,0 8,1 8,2 Petranka J. G., Fleenor D. E., K. Sykes et al. Structure of the CD59-encoding gene: further evidence of a relationship to murine lymphocyte antigen Ly-6 protein // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 1992. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.89.17.7876 — PMID:1381503
  9. ↑ Waterman C., Yates J. R. Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation // Nat. Cell Biol. — NPG, 2011. — ISSN 1465-7392; 1476-4679 — doi:10.1038/NCB2216 — PMID:21423176
  10. ↑ Petranka J. G., Fleenor D. E., K. Sykes et al. Structure of the CD59-encoding gene: further evidence of a relationship to murine lymphocyte antigen Ly-6 protein // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 1992. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.89.17.7876 — PMID:1381503
  11. ↑ Jian-Hua T., Xiao-Jie Z., Yi-Dan W. et al. Effect of glycosylphosphatidylinositol specific phospholipase D gene expression levels on complement mediated killing of leukemic cells in patients with chronic myeloid leukemia // Clin. Chim. Acta — Elsevier, 2005. — ISSN 0009-8981; 1873-3492 — doi:10.1016/J.CCCN.2005.03.045 — PMID:15907827
  12. ↑ R. Watanabe DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate // EMBO J. — NPG, 1998. — ISSN 0261-4189; 1460-2075 — doi:10.1093/EMBOJ/17.17.4920 — PMID:9724629
  13. ↑ Farina A., Lane L., Lescuyer P. et al. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine // Journal of Proteomics — Elsevier, 2013. — ISSN 1874-3919; 0165-022X — doi:10.1016/J.JPROT.2013.01.012 — PMID:23376485
  14. ↑ Pisitkun T., Tchapyjnikov D., Knepper M. A. Large-scale proteomics and phosphoproteomics of urinary exosomes // Journal of the American Society of Nephrology / J. Briggs — American Society of Nephrology, 2008. — ISSN 1046-6673; 1533-3450 — doi:10.1681/ASN.2008040406 — PMID:19056867
  15. ↑ Yates J. R. Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT) // J. Proteome Res. / J. Yates — ACS, 2009. — ISSN 1535-3893; 1535-3907 — doi:10.1021/PR800658C — PMID:19199708
  16. ↑ Palmer D. J., Kelly V. C., Smit A. et al. Human colostrum: identification of minor proteins in the aqueous phase by proteomics // Proteomics / L. Stimson — Wiley, 2006. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.200500558 — PMID:16502470
  17. ↑ Palmer D. J., Kelly V. C., Smit A. et al. Human colostrum: identification of minor proteins in the aqueous phase by proteomics // Proteomics / L. Stimson — Wiley, 2006. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.200500558 — PMID:16502470
  18. ↑ Waterman C., Yates J. R. Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation // Nat. Cell Biol. — NPG, 2011. — ISSN 1465-7392; 1476-4679 — doi:10.1038/NCB2216 — PMID:21423176
  19. ↑ Jian-Hua T., Xiao-Jie Z., Yi-Dan W. et al. Effect of glycosylphosphatidylinositol specific phospholipase D gene expression levels on complement mediated killing of leukemic cells in patients with chronic myeloid leukemia // Clin. Chim. Acta — Elsevier, 2005. — ISSN 0009-8981; 1873-3492 — doi:10.1016/J.CCCN.2005.03.045 — PMID:15907827
  20. ↑ Pickles R. J. Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense // FASEB J. — FASEB, 2009. — ISSN 0892-6638; 1530-6860 — doi:10.1096/FJ.08-119131 — PMID:19190083
  21. ↑ Buschow S. I., Stoorvogel W., Wauben M. MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis // Immunology & Cell Biology — Wiley, 2010. — ISSN 0818-9641; 1440-1711 — doi:10.1038/ICB.2010.64 — PMID:20458337
  22. ↑ Sinha A., Kislinger T. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine // Proteomics / L. Stimson — Wiley, 2013. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.201200561 — PMID:23533145
  23. ↑ Yates J. R. Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT) // J. Proteome Res. / J. Yates — ACS, 2009. — ISSN 1535-3893; 1535-3907 — doi:10.1021/PR800658C — PMID:19199708
  24. ↑ Heyningen V. v. Colocalization of the human CD59 gene to 11p13 with the MIC11 cell surface antigen // Genomics / A. Engel — Academic Press, Elsevier, 1993. — ISSN 0888-7543; 1089-8646 — doi:10.1006/GENO.1993.1293 — PMID:7691713
  25. ↑ 25,0 25,1 Mori M., Ohara O. Circulating AIM Prevents Hepatocellular Carcinoma through Complement Activation // Cell Reports — Cell Press, Elsevier, 2014. — ISSN 2211-1247; 2639-1856 — doi:10.1016/J.CELREP.2014.08.058 — PMID:25284781
  26. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланган. 18 сентябрь, 2017 тикшерелгән.
  27. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)

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