CD48

CD48
Нинди таксонда бар H. sapiens[1]
Кодлаучы ген CD48[d][1]
Молекуляр функция связывание с белками плазмы[d][2][3][4][…], antigen binding[d][5] һәм signaling receptor activity[d][5]
Күзәнәк компоненты липидный рафт[d][6], anchored component of membrane[d][5], күзәнәк мембранасы[d][5][7][5], күзәнәк мембранасы өлеше[d][8], экзосома[d][9], мембрана[d][10][11], мембрана[d][5][12], intrinsic component of plasma membrane[d][13] һәм экзосома[d][14]
Биологик процесс defense response[d][7], leukocyte migration[d][5] һәм regulation of adaptive immune response[d][5]

CD48 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[15][16]

Искәрмәләр

  1. 1,0 1,1 UniProt
  2. P Anton van der Merwe Direct measurements of heterotypic adhesion between the cell surface proteins CD2 and CD48 // BiochemistryACS, 2002. — ISSN 0006-2960; 1520-4995; 1943-295Xdoi:10.1021/BI020296GPMID:12356317
  3. Mathew S. O., Kumaresan P. R., Lee J. K. et al. Mutational analysis of the human 2B4 (CD244)/CD48 interaction: Lys68 and Glu70 in the V domain of 2B4 are critical for CD48 binding and functional activation of NK cells // J. Immunol.Baltimore: 2005. — ISSN 0022-1767; 1550-6606doi:10.4049/JIMMUNOL.175.2.1005PMID:16002700
  4. Bateman A., Wright G. J. Large-scale screening for novel low-affinity extracellular protein interactions // Genome Res.Cold Spring Harbor Laboratory Press, 2008. — ISSN 1549-5469; 1088-9051; 1054-9803doi:10.1101/GR.7187808PMID:18296487
  5. 5,0 5,1 5,2 5,3 5,4 5,5 5,6 5,7 GOA
  6. T Suzuki, N Kiyokawa, T Taguchi et al. CD24 induces apoptosis in human B cells via the glycolipid-enriched membrane domains/rafts-mediated signaling system // J. Immunol.Baltimore: 2001. — ISSN 0022-1767; 1550-6606doi:10.4049/JIMMUNOL.166.9.5567PMID:11313396
  7. 7,0 7,1 Staunton D. E., Thorley-Lawson D. A. Molecular cloning of the lymphocyte activation marker Blast-1 // EMBO J.NPG, 1987. — ISSN 0261-4189; 1460-2075doi:10.1002/J.1460-2075.1987.TB02703.XPMID:2828034
  8. Kingsmore S. F., Seldin M. F. Structure, expression, and genetic linkage of the mouse BCM1 (OX45 or Blast-1) antigen. Evidence for genetic duplication giving rise to the BCM1 region on mouse chromosome 1 and the CD2/LFA3 region on mouse chromosome 3 // J. Exp. Med.Rockefeller University Press, 1990. — ISSN 0022-1007; 1540-9538doi:10.1084/JEM.171.6.2115PMID:1693656
  9. Buschow S. I., Stoorvogel W., Wauben M. MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis // Immunology & Cell BiologyWiley, 2010. — ISSN 0818-9641; 1440-1711doi:10.1038/ICB.2010.64PMID:20458337
  10. GOA
  11. Lippert D. Defining the membrane proteome of NK cells // J. Mass Spectrom.Wiley, 2010. — ISSN 1076-5174; 1096-9888doi:10.1002/JMS.1696PMID:19946888
  12. Lippert D. Defining the membrane proteome of NK cells // J. Mass Spectrom.Wiley, 2010. — ISSN 1076-5174; 1096-9888doi:10.1002/JMS.1696PMID:19946888
  13. Kingsmore S. F., Seldin M. F. Structure, expression, and genetic linkage of the mouse BCM1 (OX45 or Blast-1) antigen. Evidence for genetic duplication giving rise to the BCM1 region on mouse chromosome 1 and the CD2/LFA3 region on mouse chromosome 3 // J. Exp. Med.Rockefeller University Press, 1990. — ISSN 0022-1007; 1540-9538doi:10.1084/JEM.171.6.2115PMID:1693656
  14. Buschow S. I., Stoorvogel W., Wauben M. MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis // Immunology & Cell BiologyWiley, 2010. — ISSN 0818-9641; 1440-1711doi:10.1038/ICB.2010.64PMID:20458337
  15. HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланган. 18 сентябрь, 2017 тикшерелгән.
  16. UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)

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