CCR1

CCR1
Нинди таксонда бар H. sapiens[1]
Кодлаучы ген CCR1[d][1]
Молекуляр функция C-C chemokine binding[d][2][3][4][…], G protein-coupled receptor activity[d][5][5], chemokine (C-C motif) ligand 5 binding[d][2][3][6][…], signal transducer activity[d][7], chemokine (C-C motif) ligand 7 binding[d][2][8], связывание с белками плазмы[d][9][10][11][…], chemokine receptor activity[d][12][5][13], C-C chemokine receptor activity[d][7][6], phosphatidylinositol phospholipase C activity[d][14], C-C chemokine receptor activity[d][5][14][15], chemokine binding[d][15], C-C chemokine binding[d][13][16][10][…], chemokine (C-C motif) ligand 7 binding[d][13][17][15] һәм chemokine (C-C motif) ligand 5 binding[d][13][14][10][…]
Күзәнәк компоненты мембрана өлеше[d][5][5], мембрана[d][5], күзәнәк мембранасы[d][5][18][9][…], күзәнәк мембранасы өлеше[d][18], наружная сторона клеточной мембраны[d][19], цитоплазма[15] һәм наружная сторона клеточной мембраны[d][20][15]
Биологик процесс negative regulation of bone mineralization[d][21], positive regulation of cell migration[d][22], positive regulation of cytosolic calcium ion concentration[d][6], chemokine-mediated signaling pathway[d][21], передача сигнала между клетками[d][14], G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger[d][18], positive regulation of monocyte chemotaxis[d][5][23], cellular calcium ion homeostasis[d][14], positive regulation of osteoclast differentiation[d][21], dendritic cell chemotaxis[d][24], negative regulation of gene expression[d][21], хемотаксис[d][25][7], cell surface receptor signaling pathway[d][12], агрегация клеток[d][26], response to wounding[d][18], иммун җавап[d][7][6], positive regulation of ERK1 and ERK2 cascade[d][21], воспалительная реакция[d][27][7], calcium ion transport[d][14], передача сигнала[d][5], Экзоцитоз[14], positive regulation of calcium ion transport[d][16], G protein-coupled receptor signaling pathway[d][5][5][5], cytokine-mediated signaling pathway[d][5][11], хемотаксис[d][11][5][15], воспалительная реакция[d][28][5][15], иммун җавап[d][5][14][15], positive regulation of cytosolic calcium ion concentration[d][14][15], calcium-mediated signaling[d][15] һәм cell chemotaxis[d][15]

CCR1 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[29][30]

Искәрмәләр

  1. ↑ 1,0 1,1 UniProt
  2. ↑ 2,0 2,1 2,2 Berkhout T. A., J Gohil, P Gonzalez et al. Selective binding of the truncated form of the chemokine CKbeta8 (25-99) to CC chemokine receptor 1(CCR1) // Biochem. Pharmacol. — Elsevier, 2000. — ISSN 0006-2952; 1873-2968 — doi:10.1016/S0006-2952(99)00354-8 — PMID:10660125
  3. ↑ 3,0 3,1 C Combadiere, Ahuja S. K., Tiffany H. L. et al. Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(alpha), MIP-1(beta), and RANTES // J. Leukoc. Biol. / L. Montaner — Wiley-Blackwell, 1996. — ISSN 0741-5400; 1938-3673 — doi:10.1002/JLB.60.1.147 — PMID:8699119
  4. ↑ Zhang N., Inan S., Inan S. et al. A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1 // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 2005. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.0406030102 — PMID:15764707
  5. ↑ 5,00 5,01 5,02 5,03 5,04 5,05 5,06 5,07 5,08 5,09 5,10 5,11 5,12 5,13 5,14 5,15 5,16 GOA
  6. ↑ 6,0 6,1 6,2 6,3 Richardson R. M., Pridgen B. C., B Haribabu et al. Regulation of the human chemokine receptor CCR1. Cross-regulation by CXCR1 and CXCR2 // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2000. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.275.13.9201 — PMID:10734056
  7. ↑ 7,0 7,1 7,2 7,3 7,4 GOA
  8. ↑ A Ben-Baruch, L Xu, Young P. R. et al. Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. C-C CKR1, a receptor for macrophage inflammatory protein-1 alpha/Rantes, is also a functional receptor for MCP3 // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1995. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.270.38.22123 — PMID:7545673
  9. ↑ 9,0 9,1 Na D. S. Human LZIP binds to CCR1 and differentially affects the chemotactic activities of CCR1-dependent chemokines // FASEB J. — FASEB, 2004. — ISSN 0892-6638; 1530-6860 — doi:10.1096/FJ.03-0867FJE — PMID:15001559
  10. ↑ 10,0 10,1 10,2 C Combadiere, Ahuja S. K., Tiffany H. L. et al. Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(alpha), MIP-1(beta), and RANTES // J. Leukoc. Biol. / L. Montaner — Wiley-Blackwell, 1996. — ISSN 0741-5400; 1938-3673 — doi:10.1002/JLB.60.1.147 — PMID:8699119
  11. ↑ 11,0 11,1 11,2 Na D. S. PLP2/A4 interacts with CCR1 and stimulates migration of CCR1-expressing HOS cells // Biochem. Biophys. Res. Commun. — Academic Press, Elsevier, 2004. — ISSN 0006-291X; 1090-2104 — doi:10.1016/J.BBRC.2004.09.118 — PMID:15474493
  12. ↑ 12,0 12,1 T Mirzadegan, F Diehl, B Ebi et al. Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundle // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2000. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M000692200 — PMID:10770925
  13. ↑ 13,0 13,1 13,2 13,3 Berkhout T. A., J Gohil, P Gonzalez et al. Selective binding of the truncated form of the chemokine CKbeta8 (25-99) to CC chemokine receptor 1(CCR1) // Biochem. Pharmacol. — Elsevier, 2000. — ISSN 0006-2952; 1873-2968 — doi:10.1016/S0006-2952(99)00354-8 — PMID:10660125
  14. ↑ 14,0 14,1 14,2 14,3 14,4 14,5 14,6 14,7 14,8 Richardson R. M., Pridgen B. C., B Haribabu et al. Regulation of the human chemokine receptor CCR1. Cross-regulation by CXCR1 and CXCR2 // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2000. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.275.13.9201 — PMID:10734056
  15. ↑ 15,00 15,01 15,02 15,03 15,04 15,05 15,06 15,07 15,08 15,09 15,10 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
  16. ↑ 16,0 16,1 Zhang N., Inan S., Inan S. et al. A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1 // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 2005. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.0406030102 — PMID:15764707
  17. ↑ A Ben-Baruch, L Xu, Young P. R. et al. Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. C-C CKR1, a receptor for macrophage inflammatory protein-1 alpha/Rantes, is also a functional receptor for MCP3 // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1995. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.270.38.22123 — PMID:7545673
  18. ↑ 18,0 18,1 18,2 18,3 H Nomura, Nielsen B. W., K Matsushima Molecular cloning of cDNAs encoding a LD78 receptor and putative leukocyte chemotactic peptide receptors // Int. Immunol. — OUP, 1993. — ISSN 0953-8178; 1460-2377 — doi:10.1093/INTIMM/5.10.1239 — PMID:7505609
  19. ↑ Lee S. C., Brummet M. E., S Shahabuddin et al. Cutaneous injection of human subjects with macrophage inflammatory protein-1 alpha induces significant recruitment of neutrophils and monocytes // J. Immunol. — Baltimore: 2000. — ISSN 0022-1767; 1550-6606 — doi:10.4049/JIMMUNOL.164.6.3392 — PMID:10706735
  20. ↑ Lee S. C., Brummet M. E., S Shahabuddin et al. Cutaneous injection of human subjects with macrophage inflammatory protein-1 alpha induces significant recruitment of neutrophils and monocytes // J. Immunol. — Baltimore: 2000. — ISSN 0022-1767; 1550-6606 — doi:10.4049/JIMMUNOL.164.6.3392 — PMID:10706735
  21. ↑ 21,0 21,1 21,2 21,3 21,4 Pozzi S., Patel K. J., P Veiby A novel role for CCL3 (MIP-1α) in myeloma-induced bone disease via osteocalcin downregulation and inhibition of osteoblast function // Leukemia — NPG, 2011. — ISSN 0887-6924; 1476-5551 — doi:10.1038/LEU.2011.43 — PMID:21403648
  22. ↑ Gilliland C. T., Salanga C. L., Kawamura T. et al. The chemokine receptor CCR1 is constitutively active, which leads to G protein-independent, β-arrestin-mediated internalization // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2013. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M113.503797 — PMID:24056371
  23. ↑ Sung H. J., Kim Y. S., Kang H. et al. Human LZIP induces monocyte CC chemokine receptor 2 expression leading to enhancement of monocyte chemoattractant protein 1/CCL2-induced cell migration // Experimental and Molecular Medicine — Springer Nature, Korean Society for Biochemistry and Molecular Biology, 2008. — ISSN 1226-3613; 2092-6413 — doi:10.3858/EMM.2008.40.3.332 — PMID:18587271
  24. ↑ Rodríguez-Fernández J. L. The multiple personalities of the chemokine receptor CCR7 in dendritic cells // J. Immunol. — Baltimore: 2006. — ISSN 0022-1767; 1550-6606 — doi:10.4049/JIMMUNOL.176.9.5153 — PMID:16621978
  25. ↑ Na D. S. PLP2/A4 interacts with CCR1 and stimulates migration of CCR1-expressing HOS cells // Biochem. Biophys. Res. Commun. — Academic Press, Elsevier, 2004. — ISSN 0006-291X; 1090-2104 — doi:10.1016/J.BBRC.2004.09.118 — PMID:15474493
  26. ↑ OM H., HF D., AK S. et al. LEC induces chemotaxis and adhesion by interacting with CCR1 and CCR8 // Blood — American Society of Hematology, Elsevier, 2000. — ISSN 0006-4971; 1528-0020 — PMID:10910894
  27. ↑ D McDermott Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor // J. Exp. Med. — Rockefeller University Press, 1993. — ISSN 0022-1007; 1540-9538 — doi:10.1084/JEM.177.5.1421 — PMID:7683036
  28. ↑ D McDermott Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor // J. Exp. Med. — Rockefeller University Press, 1993. — ISSN 0022-1007; 1540-9538 — doi:10.1084/JEM.177.5.1421 — PMID:7683036
  29. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланган. 18 сентябрь, 2017 тикшерелгән.
  30. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)

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