IGL@

Immunoglobulin lambda locus
Identificadores
Símbolos IGL; IGL@; IGLC6
IDs externos MGI96526 GeneCards: IGL Gene
Ortólogos
Espécies Humano Rato
Entrez 3535 n/a
Ensembl ENSG00000211669 n/a
UniProt Q6GMX3 n/a
RefSeq (mRNA) NG_000002 n/a
RefSeq (proteína) n/a n/a
Localização (UCSC) Chr 22:
22.27 – 23.48 Mb
Chr 16:
19.06 – 19.09 Mb
Busca PubMed [1] n/a

IGL@ ou locus lambda da imunoglobulina (também conhecido como IGL[1] e IGLC6[2]), é uma região do cromossoma 22 que contém genes para as cadeias leves lambda dos anticorpos (imunoglobulinas).[3]

Genes

O locus lambda da imunoglobulina contém os seguintes genes:

  • IGLC@ – grupo constante
    • IGLC1 – imunoglobulina lambda constante 1 (marcador Mcg)
    • IGLC2 – imunoglobulina lambda constante 2 (marcador Kern-Oz-)
    • IGLC3 – imunoglobulina lambda constante 3 (marcador Kern-Oz+)
    • IGLC7 – imunoglobulina lambda constante 7
  • IGLJ@ – grupo de união
    • IGLJn – imunoglobulina lambda união n
    • IGLJ1, IGLJ2, IGLJ3, IGLJ6, IGLJ7
  • IGLV@ – grupo variável
    • IGLVm-n – imunoglobulina lambda variável n-m
    • IGLV1-36, IGLV1-40, IGLV1-44, IGLV1-47, IGLV1-51, IGLV1-62
    • IGLV2-5, IGLV2-8, IGLV2-11, IGLV2-14, IGLV2-18, IGLV2-23
    • IGLV3-1, IGLV3-10, IGLV3-12, IGLV3-16, IGLV3-19, IGLV3-21, IGLV3-25, IGLV3-27
    • IGLV4-3, IGLV4-60, IGLV4-69
    • IGLV5-37, IGLV5-39, IGLV5-45, IGLV5-52
    • IGLV6-57
    • IGLV7-43
    • IGLV9-49
    • IGLV10-54

Referências

Bibliografia

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