S1PR2
گیرندهٔ شمارهٔ ۲ اسفنگوزین-۱-فسفات (انگلیسی: Sphingosine-1-phosphate receptor 2) یا به اختصار S1PR2 یا S1P2، یک پروتئین است که در انسان توسط ژن «S1PR2» کُدگذاری میشود.
این پروتئین نوعی گیرنده جفتشونده با پروتئین جی است و به مولکول لیپیدی پیامرسان اسفنگوزین-۱-فسفات متصل میشود.[۵] محصول حاصله در ازدیاد و تکثیر سلولی، بقا آنها و همچنین فعالشدن رونویسی دیانای نقش دارد.[۵]
منابع
- ↑ ۱٫۰ ۱٫۱ ۱٫۲ GRCh38: Ensembl release 89: ENSG00000267534 – Ensembl, May 2017
- ↑ ۲٫۰ ۲٫۱ ۲٫۲ GRCm38: Ensembl release 89: ENSMUSG00000043895 – Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ ۵٫۰ ۵٫۱ "Entrez Gene: S1PR2, sphingosine-1-phosphate receptor 2".
- مشارکتکنندگان ویکیپدیا. «S1PR2». در دانشنامهٔ ویکیپدیای انگلیسی، بازبینیشده در ۲۰ اوت ۲۰۱۹.
برای مطالعهٔ بیشتر
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- Takuwa Y (2002). "[Regulation of Rho family G proteins and cell motility by the Edg family of sphingosin 1-phosphate receptors]". Tanpakushitsu Kakusan Koso. 47 (4 Suppl): 496–502. PMID 11915348.
- MacLennan AJ, Browe CS, Gaskin AA, et al. (1994). "Cloning and characterization of a putative G-protein coupled receptor potentially involved in development". Mol. Cell. Neurosci. 5 (3): 201–9. doi:10.1006/mcne.1994.1024. PMID 8087418.
- Yamaguchi F, Tokuda M, Hatase O, Brenner S (1996). "Molecular cloning of the novel human G protein-coupled receptor (GPCR) gene mapped on chromosome 9". Biochem. Biophys. Res. Commun. 227 (2): 608–14. doi:10.1006/bbrc.1996.1553. PMID 8878560.
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- Hla T (April 2001). "Sphingosine 1-phosphate receptors". Prostaglandins. 64 (1–4): 135–142. doi:10.1016/s0090-6980(01)00109-5. PMID 11331101.
- Mazurais D, Robert P, Gout B, et al. (2002). "Cell type-specific localization of human cardiac S1P receptors". J. Histochem. Cytochem. 50 (5): 661–70. doi:10.1177/002215540205000507. PMID 11967277.
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پیوند به بیرون
- Lysophospholipid receptors در سرعنوانهای موضوعی پزشکی (MeSH) در کتابخانهٔ ملی پزشکی ایالات متحدهٔ آمریکا
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