RB1CC1

RB1CC1
معین‌کننده‌ها
نام‌های دیگرRB1CC1, ATG17, CC1, FIP200, PPP1R131, RB1 inducible coiled-coil 1
شناسه‌های بیرونیOMIM: 606837; MGI: 1341850; HomoloGene: 7659; GeneCards: RB1CC1; OMA:RB1CC1 - orthologs
هم‌ساخت‌شناسی
گونه‌هاانسانموش
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001083617
NM_014781

NM_009826

RefSeq (پروتئین)

NP_001077086
NP_055596

NP_033956

موقعیت (UCSC)Chr 8: 52.62 – 52.75 MbChr 1: 6.21 – 6.28 Mb
جستجوی PubMed[۳][۴]
ویکی‌داده
مشاهده/ویرایش انسانمشاهده/ویرایش موش

پروتئین ۱ خم‌شدۀ خمیدۀ القاشونده توسط آربی۱ (انگلیسی: RB1-inducible coiled-coil protein 1) یک پروتئین است که در انسان توسط ژن «RB1CC1» کُدگذاری می‌شود.[۵][۶][۷][۸]

این پروتئین با مولکول های PTK2B،[۹] ASK1[۱۰] و PTK2 تعامل پروتئین-پروتئین دارد.[۹]

منابع

  1. ۱٫۰ ۱٫۱ ۱٫۲ GRCh38: Ensembl release 89: ENSG00000023287Ensembl, May 2017
  2. ۲٫۰ ۲٫۱ ۲٫۲ GRCm38: Ensembl release 89: ENSMUSG00000025907Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Chano T, Ikegawa S, Kontani K, Okabe H, Baldini N, Saeki Y (Feb 2002). "Identification of RB1CC1, a novel human gene that can induce RB1 in various human cells". Oncogene. 21 (8): 1295–8. doi:10.1038/sj.onc.1205171. PMID 11850849. S2CID 1446211.
  6. Maucuer A, Camonis JH, Sobel A (Apr 1995). "Stathmin interaction with a putative kinase and coiled-coil-forming protein domains". Proceedings of the National Academy of Sciences of the United States of America. 92 (8): 3100–4. doi:10.1073/pnas.92.8.3100. PMC 42112. PMID 7724523.
  7. Hara T, Takamura A, Kishi C, Iemura S, Natsume T, Guan JL, Mizushima N (May 2008). "FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells". The Journal of Cell Biology. 181 (3): 497–510. doi:10.1083/jcb.200712064. PMC 2364687. PMID 18443221.
  8. "Entrez Gene: RB1CC1 RB1-inducible coiled-coil 1".
  9. ۹٫۰ ۹٫۱ Ueda H, Abbi S, Zheng C, Guan JL (Apr 2000). "Suppression of Pyk2 kinase and cellular activities by FIP200". The Journal of Cell Biology. 149 (2): 423–30. doi:10.1083/jcb.149.2.423. PMC 2175150. PMID 10769033.
  10. Gan B, Peng X, Nagy T, Alcaraz A, Gu H, Guan JL (Oct 2006). "Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways". The Journal of Cell Biology. 175 (1): 121–33. doi:10.1083/jcb.200604129. PMC 2064504. PMID 17015619.

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