GPR4
گیرنده ۴ جفت شده با پروتئین G پروتئینی است که در انسان توسط ژن GPR4 کدگذاری میشود.[۵][۶]
منابع
- ↑ ۱٫۰ ۱٫۱ ۱٫۲ GRCh38: Ensembl release 89: ENSG00000177464 – Ensembl, May 2017
- ↑ ۲٫۰ ۲٫۱ ۲٫۲ GRCm38: Ensembl release 89: ENSMUSG00000044317 – Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ Mahadevan MS, Baird S, Bailly JE, Shutler GG, Sabourin LA, Tsilfidis C, Neville CE, Narang M, Korneluk RG (Apr 1996). "Isolation of a novel G protein-coupled receptor (GPR4) localized to chromosome 19q13.3". Genomics. 30 (1): 84–8. doi:10.1006/geno.1995.0013. PMID 8595909.
- ↑ "Entrez Gene: GPR4 G protein-coupled receptor 4".
جهت مطالعه
- An S, Tsai C, Goetzl EJ (1996). "Cloning, sequencing and tissue distribution of two related G protein-coupled receptor candidates expressed prominently in human lung tissue". FEBS Lett. 375 (1–2): 121–4. doi:10.1016/0014-5793(95)01196-L. PMID 7498459. S2CID 9845527.
- Heiber M, Docherty JM, Shah G, et al. (1995). "Isolation of three novel human genes encoding G protein-coupled receptors". DNA Cell Biol. 14 (1): 25–35. doi:10.1089/dna.1995.14.25. PMID 7832990.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Lum H, Qiao J, Walter RJ, et al. (2003). "Inflammatory stress increases receptor for lysophosphatidylcholine in human microvascular endothelial cells". Am. J. Physiol. Heart Circ. Physiol. 285 (4): H1786–9. doi:10.1152/ajpheart.00359.2003. PMID 12805023.
- Ludwig MG, Vanek M, Guerini D, et al. (2003). "Proton-sensing G-protein-coupled receptors". Nature. 425 (6953): 93–8. Bibcode:2003Natur.425...93L. doi:10.1038/nature01905. PMID 12955148. S2CID 4395698.
- Bektas M, Barak LS, Jolly PS, et al. (2003). "The G protein-coupled receptor GPR4 suppresses ERK activation in a ligand-independent manner". Biochemistry. 42 (42): 12181–91. doi:10.1021/bi035051y. PMID 14567679.
- Sin WC, Zhang Y, Zhong W, et al. (2004). "G protein-coupled receptors GPR4 and TDAG8 are oncogenic and overexpressed in human cancers". Oncogene. 23 (37): 6299–303. doi:10.1038/sj.onc.1207838. PMID 15221007.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Kim KS, Ren J, Jiang Y, et al. (2005). "GPR4 plays a critical role in endothelial cell function and mediates the effects of sphingosylphosphorylcholine". FASEB J. 19 (7): 819–21. doi:10.1096/fj.04-2988fje. PMID 15857892. S2CID 23640250.
{{cite journal}}: نگهداری یادکرد:doi رایگان بینشان (رده) - Qiao J, Huang F, Naikawadi RP, et al. (2006). "Lysophosphatidylcholine impairs endothelial barrier function through the G protein-coupled receptor GPR4". Am. J. Physiol. Lung Cell Mol. Physiol. 291 (1): L91–101. doi:10.1152/ajplung.00508.2005. PMID 16461426.
- Huang F, Mehta D, Predescu S, et al. (2007). "A novel lysophospholipid- and pH-sensitive receptor, GPR4, in brain endothelial cells regulates monocyte transmigration". Endothelium. 14 (1): 25–34. doi:10.1080/10623320601177288. PMID 17364894.
- Zou Y, Kim CH, Chung JH, et al. (2007). "Upregulation of endothelial adhesion molecules by lysophosphatidylcholine. Involvement of G protein-coupled receptor GPR4". FEBS J. 274 (10): 2573–84. doi:10.1111/j.1742-4658.2007.05792.x. PMID 17437524. S2CID 83245004.
- Tobo M, Tomura H, Mogi C, et al. (2007). "Previously postulated "ligand-independent" signaling of GPR4 is mediated through proton-sensing mechanisms". Cell. Signal. 19 (8): 1745–53. doi:10.1016/j.cellsig.2007.03.009. PMID 17462861.
Content Disclaimer
Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.
- The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
- There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
- It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
- Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
- Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.