CLEC5A
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| نامهای دیگر | CLEC5A, CLECSF5, MDL-1, MDL1, C-type lectin domain family 5 member A, C-type lectin domain containing 5A | ||||||||||||||||||||||||||||||||||||||||||||||||||
| شناسههای بیرونی | OMIM: 604987; MGI: 1345151; HomoloGene: 8302; GeneCards: CLEC5A; OMA:CLEC5A - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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عضو A از خانوادهٔ ۵ دومِـین لکتین نوع سی (انگلیسی: C-type lectin domain family 5 member A) که با نام MDL1 هم شناخته میشود، یک پروتئین لکتین نوع سی است که در انسان توسط ژن «CLEC5A» کُدگذاری میشود.[۵][۶]
به نظر میرسد که این پروتئین، مولکولی مؤثر در مسیر فعالسازیتبار سلولی میلوئیدی باشد.
منابع
- ↑ ۱٫۰ ۱٫۱ ۱٫۲ GRCh38: Ensembl release 89: ENSG00000258227 – Ensembl, May 2017
- ↑ ۲٫۰ ۲٫۱ ۲٫۲ GRCm38: Ensembl release 89: ENSMUSG00000029915 – Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Entrez Gene: C-type lectin domain family 5".
- ↑ Bakker AB, Baker E, Sutherland GR, Phillips JH, Lanier LL (August 1999). "Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells". Proc. Natl. Acad. Sci. U.S.A. 96 (17): 9792–6. doi:10.1073/pnas.96.17.9792. PMC 22289. PMID 10449773.
- مشارکتکنندگان ویکیپدیا. «CLEC5A». در دانشنامهٔ ویکیپدیای انگلیسی، بازبینیشده در ۲۵ دسامبر ۲۰۱۹.
برای مطالعهٔ بیشتر
- Joyce-Shaikh B; et al. (2010). "Myeloid DAP12-associating lectin (MDL)-1 regulates synovial inflammation and bone erosion associated with autoimmune arthritis". J Exp Med. 207 (3): 579–89. doi:10.1084/jem.20090516. PMC 2839155. PMID 20212065.
- Chen ST, Lin YL, Huang MT, et al. (2008). "CLEC5A is critical for dengue-virus-induced lethal disease". Nature. 453 (7195): 672–6. doi:10.1038/nature07013. PMID 18496526.
- Davila S, Froeling FE, Tan A, et al. (2010). "New genetic associations detected in a host response study to hepatitis B vaccine". Genes Immun. 11 (3): 232–8. doi:10.1038/gene.2010.1. PMID 20237496.
- Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
- Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
- Ebner S, Sharon N, Ben-Tal N (2003). "Evolutionary analysis reveals collective properties and specificity in the C-type lectin and lectin-like domain superfamily". Proteins. 53 (1): 44–55. doi:10.1002/prot.10440. PMID 12945048.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Drickamer K (1999). "C-type lectin-like domains". Curr. Opin. Struct. Biol. 9 (5): 585–90. doi:10.1016/S0959-440X(99)00009-3. PMID 10508765.
- Watson AA, O'Callaghan CA (2010). "Crystallization and X-ray diffraction analysis of human CLEC5A (MDL-1), a dengue virus receptor". Acta Crystallographica Section F. 66 (Pt 1): 29–31. doi:10.1107/S1744309109047915. PMC 2805530. PMID 20057064.
پیوند به بیرون
- مکان ژنوم CLEC5A انسانی و صفحهٔ جزئیات ژنی CLEC5A در سامانه جستجوی بانک ژنی دانشگاه کالیفرنیا، سانتا کروز.
 | این یک مقالهٔ خرد زیستشناسی مولکولی است. میتوانید با گسترش آن به ویکیپدیا کمک کنید. |
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