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Rotavirus vaccine

Safety and Mechanism

The vaccines are made from weakened rotavirus[1] and are safe[1]. They can be used even in HIV/AIDS patients.[1] An earlier version of the vaccine was linked to intussusception, but the current versions are not.[2] Older recommendations were to avoid rotavirus vaccination in babies who have had intussusception.[1]

Rotasiil

Rotasiil is lyophilized pentavalent vaccine. It contain human bovine reassortant strains of rotavirus serotypes G1, G2, G3, G4 and G9. This is world's first thermostable vaccine which can be stored without refrigeration at or below 25 °C. Rotasiil is recently[when?] launched in India.This vaccine is stable for up to 18 months when stored at 40 °C.[3]

References

  1. ^ a b c d World Health Organization (2013). "Rotavirus vaccines : WHO position paper — January 2013". Weekly Epidemiological Record. 88 (5): 49–64. hdl:10665/242024. PMID 23424730. {{cite journal}}: Unknown parameter |lay-url= ignored (help)
  2. ^ Lu, Hai-Ling; Ding, Ying; Goyal, Hemant; Xu, Hua-Guo (4 October 2019). "Association Between Rotavirus Vaccination and Risk of Intussusception Among Neonates and Infants". JAMA Network Open. 2 (10): e1912458. doi:10.1001/jamanetworkopen.2019.12458. PMC 6784808. PMID 31584679.
  3. ^ Burke, Rachel M.; Tate, Jacqueline E.; Kirkwood, Carl D.; Steele, A. Duncan; Parashar, Umesh D. (2019-10). "Current and new rotavirus vaccines:". Current Opinion in Infectious Diseases. 32 (5): 435–444. doi:10.1097/QCO.0000000000000572. ISSN 0951-7375. PMC 6749957. PMID 31305493. {{cite journal}}: Check date values in: |date= (help)CS1 maint: PMC format (link)

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