User:Kkher/sandbox

The main cause of gynecomastia is an imbalance between estrogen and androgen varying from increase in estrogen production, decrease in androgen production, or a combination of both. [1]

An abnormal ratio of myo-inositol and D-chiro-inositol can be present in PCOS affecting estrogen and androgen levels. In PCOS, MI concentrations are depleted; affecting glucose intake and impairing FSH signaling needed for ovulation. DCI concentrations are increased, leading to an overproduction of androgens. Research shows that a combination of 40:1 molar ratio of myo-inositol (MI) and d-chiro-insositol (DCI) can improve metabolic and hormonal imbalances in PCOS. [2]

Welcome to my sandbox!


I am currently learning how to use wikipedia for my course. I am nervous about making edits and correcting work on a public domain. Hopefully, I become more confident.

  1. ^ Dickson, Gretchen (2012-04-01). "Gynecomastia". American Family Physician. 85 (7): 716–722. ISSN 0002-838X.
  2. ^ Unfer, Vittorio; Dinicola, Simona; Laganà, Antonio Simone; Bizzarri, Mariano (2020/1). "Altered Ovarian Inositol Ratios May Account for Pathological Steroidogenesis in PCOS". International Journal of Molecular Sciences. 21 (19): 7157. doi:10.3390/ijms21197157. {{cite journal}}: Check date values in: |date= (help)CS1 maint: unflagged free DOI (link)

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