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In endoreduplication cells skip M phase completely by exiting the mitotic cell cycle in the G2 phase after completing the S phase several times, resulting in a mononucleated polyploid cell. The cell ends up with four copies of each chromosome per repeat of the S phase. [1]


Endomitosis is a type of cell cycle variation where mitosis is initiated, but stopped in the anaphase and thus cytokinesis are not completed. The cell ends up with multiple nuclei in contrast to a cell undergoing endoreduplication. [1][2]

  1. ^ a b Zielke, N.; Edgar, B. A.; DePamphilis, M. L. (2013-01-01). "Endoreplication". Cold Spring Harbor Perspectives in Biology. 5 (1): a012948–a012948. doi:10.1101/cshperspect.a012948. ISSN 1943-0264. PMC 3579398. PMID 23284048.{{cite journal}}: CS1 maint: PMC format (link)
  2. ^ Shu, Zhiqiang; Row, Sarayu; Deng, Wu-Min (2018-06). "Endoreplication: The Good, the Bad, and the Ugly". Trends in Cell Biology. 28 (6): 465–474. doi:10.1016/j.tcb.2018.02.006. PMC 5962415. PMID 29567370. {{cite journal}}: Check date values in: |date= (help)CS1 maint: PMC format (link)

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